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  1. Article

    Efruxifermin in non-alcoholic steatohepatitis: a randomized, double-blind, placebo-controlled, phase 2a trial

    Preclinical and clinical data suggest that fibroblast growth factor 21 (FGF21) is anti-fibrotic, improves metabolic status and has potential to treat non-alcoholic steatohepatitis (NASH). We assessed the safet...

    Stephen A. Harrison, Peter J. Ruane, Bradley L. Freilich, Guy Neff in Nature Medicine (2021)

  2. Article

    Open Access

    6q25.1 (TAB2) microdeletion is a risk factor for hypoplastic left heart: a case report that expands the phenotype

    Hypoplastic left heart syndrome (HLHS) is a rare but devastating congenital heart defect (CHD) accounting for 25% of all infant deaths due to a CHD. The etiology of HLHS remains elusive, but there is increasin...

    Andrew Cheng, Whitney Neufeld-Kaiser, Peter H. Byers in BMC Cardiovascular Disorders (2020)

  3. Article

    Open Access

    Advancing Symptom Alleviation with Palliative Treatment (ADAPT) trial to improve quality of life: a study protocol for a randomized clinical trial

    People living with chronic heart failure (CHF), chronic obstructive pulmonary disease (COPD), and interstitial lung disease (ILD) suffer impaired quality of life due to burdensome symptoms and depression. The ...

    Bridget A. Graney, David H. Au, Anna E. Barón, Andrew Cheng, Sara A. Combs in Trials (2019)

  4. No Access

    Article

    Melanoma Metastatic to the Mandible: Symptoms Precede Imaging Findings

    Malignant melanoma is an aggressive and unpredictable cancer with the propensity for widespread metastasis. Whilst metastatic spread to the axial skeleton is relatively common, metastasis to the jaws is rarely...

    Anthony Noor, Andrew Cheng, Paul Sambrook in Journal of Maxillofacial and Oral Surgery (2018)

  5. Article

    Open Access

    Left Atrial Diameter is an Independent Predictor of Postoperative Atrial Fibrillation after Minimally Invasive Mitral Valve Surgery

    Andrew Cheng, Hansraj R Bookun, Michael Rasmussen in Journal of Cardiothoracic Surgery (2015)

  6. Article

    Open Access

    Mini-Thoracotomy Access Reduces the Incidence of Postoperative Atrial Fibrillation after Aortic Valve Replacement

    Hansraj R Bookun, Andrew Cheng, Chin Siew Lee in Journal of Cardiothoracic Surgery (2015)

  7. Article

    Open Access

    Sutureless bioprosthesis may increase postoperative atrial fibrillation after aortic valve replacement

    Sameer D Thakur, Andrew Cheng, Hansraj R Bookun in Journal of Cardiothoracic Surgery (2015)

  8. No Access

    Article

    Leptin controls adipose tissue lipogenesis via central, STAT3–independent mechanisms

    Leptin (encoded by Lep) controls body weight by regulating food intake and fuel partitioning. Obesity is characterized by leptin resistance and increased endocannabinoid tone. Here we show that leptin infused int...

    Christoph Buettner, Evan D Muse, Andrew Cheng, Linghong Chen in Nature Medicine (2008)

  9. Article

    Nasogastric tubes after cardiac surgery: Impact on nausea and vomiting

    Yuji Hirasaki, Hyunju Jung, Leonid Minkovich in Canadian Journal of Anesthesia (2005)

  10. Article

    Detecting Earth-like planets (reply)

    ROGER ANGEL, ANDREW CHENG, NEVILLE WOOLF in Nature (1986)

  11. No Access

    Article

    Supernovae in close binaries

    The impact of a supernova shell onto 2.82M and 20.0M main-sequence stars is investigated for various initial orbital separations, and various supernova shell masses and velocities. The inelastic collision bet...

    Andrew Cheng in Astrophysics and Space Science (1974)