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  1. Article

    Open Access

    Gap Junctions May Have A Computational Function In The Cerebellum: A Hypothesis

    In the cerebellum, granule cells make parallel fibre contact on (and excite) Golgi cells and Golgi cells inhibit granule cells, forming an open feedback loop. Parallel fibres excite Golgi cells synaptically, e...

    Mike Gilbert, Anders Rasmussen in The Cerebellum (2024)

  2. Article

    Open Access

    The Effect of Nucleo-Olivary Stimulation on Climbing Fiber EPSPs in Purkinje Cells

    Climbing fibers, connecting the inferior olive and Purkinje cells, form the nervous system's strongest neural connection. These fibers activate after critical events like motor errors or anticipation of reward...

    Josefine Öhman, Elias Sjölin, Maurizio Cundari, Fredrik Johansson in The Cerebellum (2024)

  3. Article

    Open Access

    The ability to maintain rhythm is predictive of ADHD diagnosis and profile

    Attention deficit hyperactivity disorder (ADHD) is the most prevalent neuropsychiatric disorder in the world. Currently, the diagnosis is based mainly on interviews, resulting in uncertainties in the clinical ...

    Peik Gustafsson, Katarina Kjell, Maurizio Cundari, Martin Larsson in BMC Psychiatry (2023)

  4. Article

    Open Access

    Effects of working memory load and CS-US intervals on delay eyeblink conditioning

    Eyeblink conditioning is used in many species to study motor learning and make inferences about cerebellar function. However, the discrepancies in performance between humans and other species combined with evi...

    Leila Etemadi, Dan-Anders Jirenhed, Anders Rasmussen in npj Science of Learning (2023)

  5. Article

    Open Access

    Weak correlations between cerebellar tests

    Eyeblink conditioning, finger tap**, and prism adaptation are three tasks that have been linked to the cerebellum. Previous research suggests that these tasks recruit distinct but partially overlap** parts...

    Karolina Löwgren, Rasmus Bååth, Anders Rasmussen in Scientific Reports (2020)

  6. Article

    Open Access

    Characterizing chromatin landscape from aggregate and single-cell genomic assays using flexible duration modeling

    ATAC-seq has become a leading technology for probing the chromatin landscape of single and aggregated cells. Distilling functional regions from ATAC-seq presents diverse analysis challenges. Methods commonly u...

    Mariano I. Gabitto, Anders Rasmussen, Orly Wapinski in Nature Communications (2020)

  7. Article

    Open Access

    Absence of Parallel Fibre to Purkinje Cell LTD During Eyeblink Conditioning

    Long-term depression (LTD) of parallel fibre/Purkinje cell synapses has been the favoured explanation for cerebellar motor learning such as classical eyeblink conditioning. Previous evidence against this inter...

    Fredrik Johansson, Dan-Anders Jirenhed, Anders Rasmussen in Scientific Reports (2018)

  8. Article

    Open Access

    Learning and Timing of Voluntary Blink Responses Match Eyeblink Conditioning

    Can humans produce well-timed blink responses to a neutral stimulus voluntarily, without receiving any blink-eliciting, unconditional, stimulus? And if they can, to what degree does classical eyeblink conditio...

    Anders Rasmussen, Dan-Anders Jirenhed in Scientific Reports (2017)

  9. No Access

    Article

    Simple and Complex Spike Firing Patterns in Purkinje Cells During Classical Conditioning

    Classical blink conditioning is known to depend critically on the cerebellum and the relevant circuitry is gradually being unravelled. Several lines of evidence support the theory that the conditioned stimulus...

    Anders Rasmussen, Dan-Anders Jirenhed, Germund Hesslow in The Cerebellum (2008)