13 Result(s)

Article

On the use of solid ¹³³Ba sources as surrogate for liquid ¹³¹I in SPECT/CT calibration: a European multi-centre evaluation

Commissioning, calibration, and quality control procedures for nuclear medicine imaging systems are typically performed using hollow containers filled with radionuclide solutions. This leads to multiple source...

Johannes Tran-Gia, Ana M. Denis-Bacelar, Kelley M. Ferreira… in EJNMMI Physics (2023)

Article

Quantitative validation of Monte Carlo SPECT simulation: application to a Mediso AnyScan GATE simulation

Monte Carlo (MC) simulations are used in nuclear medicine imaging as they provide unparalleled insight into processes that are not directly experimentally measurable, such as scatter and attenuation in an acqu...

Sophia Pells, David M. Cullen, Daniel Deidda, Ana M. Denis-Bacelar… in EJNMMI Physics (2023)

Article

Triple modality image reconstruction of PET data using SPECT, PET, CT information increases lesion uptake in images of patients treated with radioembolization with \(^{90}Y\) micro-spheres

Nuclear medicine imaging modalities like computed tomography (CT), single photon emission CT (SPECT) and positron emission tomography (PET) are employed in the field of theranostics to estimate and plan the do...

Daniel Deidda, Ana M. Denis-Bacelar, Andrew J. Fenwick… in EJNMMI Physics (2023)

Article

EANM practice guideline for quantitative SPECT-CT

Quantitative SPECT-CT is a modality of growing importance with initial developments in post radionuclide therapy dosimetry, and more recent expansion into bone, cardiac and brain imaging together with the conc...

John C. Dickson, Ian S. Armstrong… in European Journal of Nuclear Medicine and M… (2023)

Article

Towards accurate partial volume correction in ^99mTc oncology SPECT: perturbation for case-specific resolution estimation

Currently, there is no consensus on the optimal partial volume correction (PVC) algorithm for oncology imaging. Several existing PVC methods require knowledge of the reconstructed resolution, usually as the po...

Rebecca Gillen, Kjell Erlandsson, Ana M. Denis-Bacelar, Kris Thielemans… in EJNMMI Physics (2022)

Article

Joint EANM, SNMMI and IAEA enabling guide: how to set up a theranostics centre

The theranostics concept using the same target for both imaging and therapy dates back to the middle of the last century, when radioactive iodine was first used to treat thyroid diseases. Since then, radioiodi...

Ken Herrmann, Luca Giovanella, Andrea Santos… in European Journal of Nuclear Medicine and M… (2022)

Article

Hybrid kernelised expectation maximisation for Bremsstrahlung SPECT reconstruction in SIRT with ⁹⁰Y micro-spheres

Selective internal radiation therapy with Yttrium-90 microspheres is an effective therapy for liver cancer and liver metastases. Yttrium-90 is mainly a high-energy beta particle emitter. These beta particles e...

Daniel Deidda, Ana M. Denis-Bacelar, Andrew J. Fenwick… in EJNMMI Physics (2022)

Article

A multicentre and multi-national evaluation of the accuracy of quantitative Lu-177 SPECT/CT imaging performed within the MRTDosimetry project

Patient-specific dosimetry is required to ensure the safety of molecular radiotherapy and to predict response. Dosimetry involves several steps, the first of which is the determination of the activity of the r...

Johannes Tran-Gia, Ana M. Denis-Bacelar, Kelley M. Ferreira… in EJNMMI Physics (2021)

Article

Reply to ‘Single high dose versus repeated bone-targeted radionuclide therapy’

Ana M. Denis-Bacelar, Sarah J. Chittenden… in European Journal of Nuclear Medicine and M… (2018)

Article

The potential of ²²³Ra and ¹⁸F-fluoride imaging to predict bone lesion response to treatment with ²²³Ra-dichloride in castration-resistant prostate cancer

The aims of this study were to calculate bone lesion absorbed doses resulting from a weight-based administration of ²²³Ra-dichloride, to assess the relationship between those doses and corresponding ¹⁸F-fluoride ...

Iain Murray, Sarah J. Chittenden… in European Journal of Nuclear Medicine and M… (2017)

Article

Phase I/II trials of ¹⁸⁶Re-HEDP in metastatic castration-resistant prostate cancer: post-hoc analysis of the impact of administered activity and dosimetry on survival

To investigate the role of patient-specific dosimetry as a predictive marker of survival and as a potential tool for individualised molecular radiotherapy treatment planning of bone metastases from castration-...

Ana M. Denis-Bacelar, Sarah J. Chittenden… in European Journal of Nuclear Medicine and M… (2017)

Article

Pre-clinical quantitative imaging and mouse-specific dosimetry for ¹¹¹In-labelled radiotracers

Accurate quantification in molecular imaging is essential to improve the assessment of novel drugs and compare the radiobiological effects of therapeutic agents prior to in-human studies. The aim of this study...

Ana M. Denis-Bacelar, Sarah E. Cronin, Chiara Da Pieve, Rowena L. Paul… in EJNMMI Research (2016)