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Life Sciences
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Understanding the termite resistance of Malaysian commercial bamboo for various applications
Bamboo nodes are an important component for increasing the hardness and stability of growth. However, little is known about how bamboo nodes affect resistance to biological control agents for industrial use. T...
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The Nephroprotective Effect of In Utero Administration of Green Synthesized Titanium Dioxide Nanoparticles in Albino Rats
Titanium dioxide nanoparticles (TiO2-NPs) are one of the most popular nanoscale materials and have a wide range of applications in the manufacturing industry; nonetheless, researchers’ focus has been directed to ...
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Metagenomic Next-Generation Sequencing as an Effective Diagnostic Tool for Talaromycosis in HIV-Negative Patients
The diagnosis of Talaromyces marneffei infection in HIV-negative patients remains challenging. There is an urgent need for rapid and convenient methods to diagnose this complicated disease. The aim of this study ...
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Open AccessDerivation of two iPSC lines (KAIMRCi004-A, KAIMRCi004-B) from a Saudi patient with Biotin-Thiamine-responsive Basal Ganglia Disease (BTBGD) carrying homozygous pathogenic missense variant in the SCL19A3 gene
The neurometabolic disorder known as biotin-thiamine-responsive basal ganglia disease (BTBGD) is a rare autosomal recessive condition linked to bi-allelic pathogenic mutations in the SLC19A3 gene. BTBGD is charac...
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Quadruplex qPCR for detection and discrimination of C. Coli,C. fetus, and C. Jejuni from other Campylobacter species in chicken and sheep meat
Campylobacter is gram-negative bacteria considered the predominant genera isolated from poultry samples and associated with gastroenteritis. Due to the problems in conventional cultural methods of time-consuming ...
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AlphaFold3 takes a step toward decoding molecular behavior and biological computation
AlphaFold 3 represents a breakthrough in predicting the 3D structures of complexes directly from their sequences, offering insights into biomolecular interactions. Extending predictions to molecular behavior a...
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Early Detection of Potato Disease Using an Enhanced Convolutional Neural Network-Long Short-Term Memory Deep Learning Model
Potato diseases pose a significant threat to farmers, impacting potato crops’ productivity, quality, and financial stability. Among the most notorious diseases is late blight, caused by Phytophthora infestans, fa...
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Mangrove (Avicennia marina) Conservation Contributed to a Higher Carbon Sequestration Rate at Protected Sites Compared to Overgrazed Mangrove Forests
Coastal mangrove ecosystems have been degraded due to changes in land use and grazing. Here, we assess the differences in population characteristics and sediment organic carbon (SOC) stocks and carbon sequestr...
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Multi-element Contamination and Health Risks in Green Leafy Vegetables from Ambagarh Chowki, Chhattisgarh, India
Leafy plants are commonly consumed as vegetables in India due to their high nutrient and vitamin content. This study, conducted in Ambagarh Chowki (India), investigated the accumulation potential of 52 element...
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Elucidating the role of prickly pear fruits (Opuntia littoralis) in mitigation of cadmium toxicity in Nile tilapia: impacts on haemato-biochemical and immunological responses
The study aimed to assess the promotional effects of dietary fruits of the prickly pear (Opuntia littoralis) on growth, haemato-biochemical, antioxidant, and immune activity and its possible regulatory roles afte...
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Exogenous Application of Tyrosine Mitigated the Adversities of Drought Stress in Maize Seedlings through Modulation of Photosynthetic Performance and Antioxidants Defense Systems
Scarcity of water is a major challenge to global food security, because productivity of food crops has significantly declined. However, the protective role of tyrosine in alleviating the adversities of drought...
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Pyridoxine-HCl Plus Gypsum and Humic Acid Reinforce Salinity Tolerance of Coriander Plants with Boosting Yield and Modifying Oil Fractionations
Despite soil salinity is one of the prime abiotic stresses, exploiting the saline soils for the agricultural production will increase in the forthcoming decades to fulfill the human food requirements. Of cours...
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Mechanisms of Bleomycin-induced Lung Fibrosis: A Review of Therapeutic Targets and Approaches
Pulmonary toxicity is a serious side effect of some specific anticancer drugs. Bleomycin is a well-known anticancer drug that triggers severe reactions in the lungs. It is an approved drug that may be prescrib...
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Heavy Metal Concentrations in Water, Sediment, and Fish Species in Chashma Barrage, Indus River: A Comprehensive Health Risk Assessment
The increasing levels of heavy metals in aquatic environments, driven by human activities, pose a critical threat to ecosystems’ overall health and sustainability. This study investigates the bioaccumulation o...
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Consortium of Endophytic Bacillus australimaris CK11 and Staphylococcus epidermidis CK9 from Commiphora gileadensis Mediates Tomato Resilience to Combined Salinity, Heat, and Drought Stresses
Climate change poses a critical threat to global agriculture. Plant growth-promoting bacteria (PGPB) present a sustainable approach to increase climate resilience. The study focused on isolating and screening ...
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Open AccessImmunomodulatory and antioxidant properties of Sarcophaga argyrostoma larval hemolymph: utilizing the Biomphalaria alexandrina snail as a model
In recent years, there has been a growing interest in exploring novel natural sources for antioxidant and anti-inflammatory agents, driven by the need for alternative therapeutic strategies with fewer side eff...
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Screening of pslA and pelB Biofilm-Producing Genes from Pseudomonas Isolated from Clinical Samples
The Pseudomonas aeruginosa bacterium, which is considered a nosocomial infectious agent, changes its structure due to exposure to various antibiotics and becomes relatively resistant to them, which makes it diffi...
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Evaluation of Bone Turnover Markers in Patients with Acute and Chronic Leukemia
This study investigated different bone biomarkers (cross-linked carboxy-terminal telopeptide of type 1 collagen (CTX-1), pyridinoline (PYD), osteocalcin (OC), interleukin-6 receptor (IL-6R), calcium (Ca), and ...
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Perindopril Dampens Cd-induced Nephrotoxicity by Suppressing Inflammatory Burden, Ang II/Ang 1–7, and Apoptosis Signaling Pathways
Cadmium (Cd) is one of the most abundant toxic heavy metals, and its exposure is linked to serious kidney intoxication, a major health problem. Evidence reported that inflammatory damage is a key factor in Cd ...
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Open AccessVirtual reality-empowered deep-learning analysis of brain cells
Automated detection of specific cells in three-dimensional datasets such as whole-brain light-sheet image stacks is challenging. Here, we present DELiVR, a virtual reality-trained deep-learning pipeline for de...
