4 Result(s)
within
English
Behavioral Sciences
Medicine/Public Health, general
A F McRae
Article
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Article
Open AccessMonozygotic twins affected with major depressive disorder have greater variance in methylation than their unaffected co-twin
Our understanding of major depressive disorder (MDD) has focused on the influence of genetic variation and environmental risk factors. Growing evidence suggests the additional role of epigenetic mechanisms inf...
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Article
Open Access708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits
A balanced t(1;11) translocation that transects the Disrupted in schizophrenia 1 (DISC1) gene shows genome-wide significant linkage for schizophrenia and recurrent major depressive disorder (rMDD) in a single lar...
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Article
Open AccessAn epigenome-wide association study meta-analysis of educational attainment
The epigenome is associated with biological factors, such as disease status, and environmental factors, such as smoking, alcohol consumption and body mass index. Although there is a widespread perception that ...
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Article
Open AccessA DNA methylation biomarker of alcohol consumption
The lack of reliable measures of alcohol intake is a major obstacle to the diagnosis and treatment of alcohol-related diseases. Epigenetic modifications such as DNA methylation may provide novel biomarkers of ...
