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Article
Construction of a mitochondria-targeted probe to monitor cysteine levels in cancer cells and zebrafish
Cysteine (Cys) plays an indispensable role as an antioxidant in the maintenance of bioredox homeostasis. We have constructed an efficient fluorescent probe Mito-Cys based on the binding of indole and naphthol....
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Article
Open AccessA chromosomal-scale genome assembly of modern cultivated hybrid sugarcane provides insights into origination and evolution
Sugarcane is a vital crop with significant economic and industrial value. However, the cultivated sugarcane’s ultra-complex genome still needs to be resolved due to its high ploidy and extensive recombination ...
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Article
Can China reach the CO2 peak by 2030? A forecast perspective
With the continuous emission of greenhouse gases, climate issues such as global warming have attracted widespread attention. As the largest CO2 emitter, China proposes the target of reaching the CO2 emissions pea...
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Article
Open AccessRumor detection on social media using hierarchically aggregated feature via graph neural networks
In the era of the Internet and big data, online social media platforms have been develo** rapidly, which accelerate rumors circulation. Rumor detection on social media is a worldwide challenging task due to ...
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Article
Long-term continuous monitoring of microRNA in living cells using modified gold nanoprobe
Long-term and continuous monitoring of the microRNA (miRNA) expression in living cells is essential in biomedical research, but it is currently limited by fast consumption and easy digestion of probes in the i...
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Article
Lepr+ mesenchymal cells sense diet to modulate intestinal stem/progenitor cells via Leptin–Igf1 axis
Diet can impact on gut health and disease by modulating intestinal stem cells (ISCs). However, it is largely unknown if and how the ISC niche responds to diet and influences ISC function. Here, we demonstrate ...
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Article
Biomimetic strategy to synthesize a strong, tough and elastic cellulose enhanced magnetic hydrogel
Magnetic hydrogels have been widely utilized in the fields of biomedical devices, flexible electronics, and soft robotics. Unfortunately, current strategies to synthesize magnetic hydrogels are difficult to ac...
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Article
A topology optimization method for hyperelastic porous structures subject to large deformation
Porous infill, rather than the solids, can provide high stiffness-to-weight ratio, energy absorption, thermal insulation, and many other outstanding properties. However, porous structure design to date have be...
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Article
A three-shell supramolecular complex enables the symmetry-mismatched chemo- and regioselective bis-functionalization of C60
Molecular Russian dolls (matryoshkas) have proven useful for testing the limits of preparative supramolecular chemistry but applications of these architectures to problems in other fields are elusive. Here we ...
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Article
Open AccessA differentially private distributed data mining scheme with high efficiency for edge computing
A wide range of data mining applications benefit from the low latency offered by edge computing. However, edge computing suffers from limited computing resources, which inhibits the applications of the computa...
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Article
Data Integrity Attack Detection for Node Voltage in Cyber-Physical Power System
In order to accurately detect the false data injection attack for node voltage in the cyber-physical power system, an attack detection method based on recurrent neural network (RNN) is proposed in this paper. ...
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Article
Field Evaluation of New Promising Sugarcane Cultivars for Cold Tolerance in Guangxi, China
Sugarcane often suffers from low-temperature stress in Guangxi, China. In this study, the cold tolerance potential of 20 new sugarcane varieties was evaluated on the basis of chlorophyll content (Chl), chlorop...
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Article
The Msi1-mTOR pathway drives the pathogenesis of mammary and extramammary Paget’s disease
Mammary and extramammary Paget’s Diseases (PD) are a malignant skin cancer characterized by the appearance of Paget cells. Although easily diagnosed, its pathogenesis remains unknown. Here, single-cell RNA-seq...
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Article
Open Access16S rRNA gene sequencing reveals an altered composition of the gut microbiota in chickens infected with a nephropathogenic infectious bronchitis virus
Infectious bronchitis virus (IBV), a member of the Coronaviridae family, causes serious losses to the poultry industry. Intestinal microbiota play an important role in chicken health and contribute to the defe...
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Article
A forward fast media independent handover control scheme for Proxy Mobile IPv6 (FFMIH-PMIPv6) over heterogeneous wireless mobile network
Proxy Mobile IPv6 (PMIPv6) is a networked-based handover protocol for the IP layer, i.e., the layer 3 mobility management protocol. In this work, we integrate fast handover and IEEE 802.21 Media Independent Ha...
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Article
Maximum data delivery probability-oriented routing protocol in opportunistic mobile networks
Some recent studies utilize node contact patterns to aid the design of routing protocol in Opportunistic Mobile Networks (OppNets). However, most existing studies only utilize one hop contact information to de...
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Article
Predicting temporal centrality in Opportunistic Mobile Social Networks based on social behavior of people
Predicting the centrality of nodes is a significant problem for different applications in Opportunistic Mobile Social Networks (OMSNs). However, when calculating such metrics, current studies focused on analy...
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Article
Open AccessAn efficient traceable access control scheme with reliable key delegation in mobile cloud computing
With the increasing number of mobile applications and the popularity of cloud computing, the combination of these two techniques that named mobile cloud computing (MCC) attracts great attention in recent years...
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Article
Fabrication of polyacrylate core–shell nanoparticles via spray drying method
Fine polyacrylate particles are thought to be environmental plastisols for car industry. However, these particles are mainly dried through demulsification of the latexes, which is not reproducible and hard to ...
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Article
Open AccessA small molecular agent YL529 inhibits VEGF-D-induced lymphangiogenesis and metastasis in preclinical tumor models in addition to its known antitumor activities
The lymph node metastasis is a key early step of the tumor metastatic process. VEGFD-mediated tumor lymphangiogenesis plays a key role, since down-regulation of p-VEGFR-3 could block the lymph node metastasis....
