4,326 Result(s)
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Open AccessAnalysis of clinicopathological characteristics and prognosis on primary gastric adenosquamous carcinoma
Primary gastric adenosquamous carcinoma (PGASC) is a rare type of gastric cancer with limited research and poorly understood clinicopathological features. This study investigated the clinicopathological featur...
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Open AccessUnlocking the potential of biogas systems for energy production and climate solutions in rural communities
On-site conversion of organic waste into biogas to satisfy consumer energy demand has the potential to realize energy equality and mitigate climate change reliably. However, existing methods ignore either real...
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Open AccessSubstantial differences in source contributions to carbon emissions and health damage necessitate balanced synergistic control plans in China
China’s strategy to concurrently address climate change and air pollution mitigation is hindered by a lack of comprehensive information on source contributions to health damage and carbon emissions. Here we sh...
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Open AccessModel based on the automated AI-driven CT quantification is effective for the diagnosis of refractory Mycoplasma pneumoniae pneumonia
The prediction of refractory Mycoplasma pneumoniae pneumonia (RMPP) remains a clinically significant challenge. This study aimed to develop an early predictive model utilizing artificial intelligence (AI)-deri...
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Open AccessIntraspecific diploidization of a halophyte root fungus drives heterosis
How organisms respond to environmental stress is a key topic in evolutionary biology. This study focused on the genomic evolution of Laburnicola rhizohalophila, a dark-septate endophytic fungus from roots of a ha...
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Open AccessHigh-density vertical sidewall MoS2 transistors through T-shape vertical lamination
Vertical transistors, in which the source and drain are aligned vertically and the current flow is normal to the wafer surface, have attracted considerable attention recently. However, the realization of high-...
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Open AccessTunable quantum emitters on large-scale foundry silicon photonics
Controlling large-scale many-body quantum systems at the level of single photons and single atomic systems is a central goal in quantum information science and technology. Intensive research and development ha...
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Open AccessDecreased ENSO post-2100 in response to formation of a permanent El Niño-like state under greenhouse warming
Under transient greenhouse warming, El Niño-Southern Oscillation (ENSO) is projected to increase pre-2100, accompanied by an easier establishment of atmospheric convection in the equatorial eastern Pacific, wh...
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Open AccessProgrammed cell death regulator BAP2 is required for IRE1-mediated unfolded protein response in Arabidopsis
Environmental and physiological situations can challenge the balance between protein synthesis and folding capacity of the endoplasmic reticulum (ER) and cause ER stress, a potentially lethal condition. The un...
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Open AccessDesign of 3D printing osteotomy block for foot based on triply periodic minimal surface
The ankle joint, which connects the lower limbs and the sole of the foot, is prone to sprain during walking and sports, which leads to ankle arthritis. Supratroleolar osteotomy is an ankle preserving operation...
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Open AccessPerturbation of METTL1-mediated tRNA N7- methylguanosine modification induces senescence and aging
Cellular senescence is characterized by a decrease in protein synthesis, although the underlying processes are mostly unclear. Chemical modifications to transfer RNAs (tRNAs) frequently influence tRNA activity...
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Open AccessPreferential evaluation of coal filling mining scheme under building pressure based on improved grey target decision-making model of game theory
The problem of coal compression under buildings is common in underground mining of coal mines in China. The selection of traditional mining programme is subjective and lacks scientific rationality. In order to...
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Open AccessPlasma metabolomics reveals the shared and distinct metabolic disturbances associated with cardiovascular events in coronary artery disease
Risk prediction for subsequent cardiovascular events remains an unmet clinical issue in patients with coronary artery disease. We aimed to investigate prognostic metabolic biomarkers by considering both shared...
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Open AccessDonor-acceptor bulk-heterojunction sensitizer for efficient solid-state infrared-to-visible photon up-conversion
Solid-state infrared-to-visible photon up-conversion is important for spectral-tailoring applications. However, existing up-conversion systems not only suffer from low efficiencies and a need for high excitati...
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Open AccessInhibition of topoisomerase 2 catalytic activity impacts the integrity of heterochromatin and repetitive DNA and leads to interlinks between clustered repeats
DNA replication and transcription generate DNA supercoiling, which can cause topological stress and intertwining of daughter chromatin fibers, posing challenges to the completion of DNA replication and chromos...
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Open AccessGenetically encoded Nδ-vinyl histidine for the evolution of enzyme catalytic center
Genetic code expansion has emerged as a powerful tool for precisely introducing unnatural chemical structures into proteins to improve their catalytic functions. Given the high catalytic propensity of histidin...
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Open AccessHybrid ant colony-based inter-cluster routing protocol for FANET
This study addresses the challenges in large-scale unmanned aerial vehicle (UAV) clusters, specifically the scalability issues and limitations of using reactive routing protocols for inter-cluster routing. The...
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Open AccessStudy on the failure mechanism of high-temperature granite under two cooling modes
In the geothermal development of hot dry rock (HDR), both the drilling of the wellbore and the heat exchange of the heat reservoir involve the effects of different cold and hot conditions on the high-temperatu...
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Open AccessA semantic feature enhanced YOLOv5-based network for polyp detection from colonoscopy images
Colorectal cancer (CRC) is a common digestive system tumor with high morbidity and mortality worldwide. At present, the use of computer-assisted colonoscopy technology to detect polyps is relatively mature, bu...
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Open AccessReformulating lipid nanoparticles for organ-targeted mRNA accumulation and translation
Fully targeted mRNA therapeutics necessitate simultaneous organ-specific accumulation and effective translation. Despite some progress, delivery systems are still unable to fully achieve this. Here, we reformu...
