2,720 Result(s)

Article

Correction to: Knock‑Down of CD24 in Astrocytes Aggravates Oxyhemoglobin‑Induced Hippocampal Neuron Impairment

**ang‑**n Chen, Tao Tao, Sen Gao, Han Wang, **ao‑Ming Zhou… in Neurochemical Research (2024)

Article

Correction to: The Mfn1‑βIIPKC Interaction Regulates Mitochondrial Dysfunction via Sirt3 Following Experimental Subarachnoid Hemorrhage

Tao Chen, Yue Wang, Yu-Hai Wang, Chun-Hua Hang in Translational Stroke Research (2024)

Article

Correction to: Gas6 Promotes Microglia Efferocytosis and Suppresses Inflammation Through Activating Axl/Rac1 Signaling in Subarachnoid Hemorrhage Mice

Junjia Tang, Yichao **, Feng Jia, Tao Lv, Anatol Manaenko… in Translational Stroke Research (2024)

Article

Investigating distinct clinical features and constructing a nomogram model for survival probability in adults with cerebellar high-grade gliomas

The clinical features of cerebellar high-grade gliomas (cHGGs) in adults have not been thoroughly explored. This large-scale, population-based study aimed to comprehensively outline these traits and construct ...

Tao Chang, Rui Zhang, Jiahao Gan, Yuan Yang, Yanhui Liu, Yan Ju, **aodong Niu… in BMC Cancer (2024)

Article

A systematic strategy for identifying causal single nucleotide polymorphisms and their target genes on Juvenile arthritis risk haplotypes

Although genome-wide association studies (GWAS) have identified multiple regions conferring genetic risk for juvenile idiopathic arthritis (JIA), we are still faced with the task of identifying the single nucl...

Kaiyu Jiang, Tao Liu, Susan Kales, Ryan Tewhey, Dongkyeong Kim… in BMC Medical Genomics (2024)

Article

The Role of the Intestinal Flora and Its Derivatives in Neurocognitive Disorders: A Narrative Review from Surgical Perspective

Perioperative neurocognitive dysfunction is a significant concern for population health, impacting postoperative recovery and increasing the financial burden on patients. With an increasing number of surgical ...

Jian Huang, Tian-Shou Qin, Yun Bo, Yu-** Li, Rong-Sheng Liu… in Molecular Neurobiology (2024)

Article

Author Correction: LINE-1 transcription activates long-range gene expression

**ufeng Li, Luyao Bie, Yang Wang, Yaqiang Hong, Ziqiang Zhou, Yiming Fan… in Nature Genetics (2024)

Article

Unbiasedly decoding the tumor microenvironment with single-cell multiomics analysis in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy with a poor prognosis and limited therapeutic options. Research on the tumor microenvironment (TME) of PDAC has propelled the developme...

Yifan Fu, **xin Tao, Tao Liu, Yueze Liu, Jiangdong Qiu, Dan Su… in Molecular Cancer (2024)

Article

METTL3-mediated NDUFB5 m6A modification promotes cell migration and mitochondrial respiration to promote the wound healing of diabetic foot ulcer

Diabetic foot ulcer (DFU) is the most devastating complication of diabetes mellitus (DM) and plays a major role in disability and death in DM patients. NADH: ubiquinone oxidoreductase subunit B5 (NDUFB5) plays...

Tao Wang, Xu Li, Yue Tao, **aojun Wang, Limeng Li… in Journal of Translational Medicine (2024)

Article

A positive feedback loop between PFKP and c-Myc drives head and neck squamous cell carcinoma progression

The aberrant expression of phosphofructokinase-platelet (PFKP) plays a crucial role in the development of various human cancers by modifying diverse biological functions. However, the precise molecular mechani...

Weiwei Liu, Zhao Ding, Ye Tao, Shixian Liu, Maoyu Jiang, Fangzheng Yi… in Molecular Cancer (2024)

Article

Synthetic CT generation for pelvic cases based on deep learning in multi-center datasets

To investigate the feasibility of synthesizing computed tomography (CT) images from magnetic resonance (MR) images in multi-center datasets using generative adversarial networks (GANs) for rectal cancer MR-onl...

**anan Li, Lecheng Jia, Fengyu Lin, Fan Chai, Tao Liu, Wei Zhang… in Radiation Oncology (2024)

Article

Development and validation of an automated Tomotherapy planning method for cervical cancer

This study aimed to develop an automated Tomotherapy (TOMO) planning method for cervical cancer treatment, and to validate its feasibility and effectiveness.

Feiru Han, Yi Xue, Sheng Huang, Tong Lu, Yining Yang, Yuanjie Cao… in Radiation Oncology (2024)

Article

Quantitative transport map** of multi-delay arterial spin labeling MRI detects early blood perfusion alterations in Alzheimer’s disease

Quantitative transport map** (QTM) of blood velocity, based on the transport equation has been demonstrated higher accuracy and sensitivity of perfusion quantification than the traditional Kety’s method-base...

Yihao Guo, Liangdong Zhou, Yi Li, Gloria C. Chiang… in Alzheimer's Research & Therapy (2024)

Article

Neoadjuvant chemotherapy with or without camrelizumab in resectable esophageal squamous cell carcinoma: the randomized phase 3 ESCORT-NEO/NCCES01 trial

Recent single-arm studies involving neoadjuvant camrelizumab, a PD-1 inhibitor, plus chemotherapy for resectable locally advanced esophageal squamous cell carcinoma (LA-ESCC) have shown promising results. This...

Jianjun Qin, Liyan Xue, Anlin Hao, **aofeng Guo, Tao Jiang, Yunfeng Ni… in Nature Medicine (2024)

Article

The cuproptosis-related signature predicts the prognosis and immune microenvironments of primary diffuse gliomas: a comprehensive analysis

Evidence has revealed a connection between cuproptosis and the inhibition of tumor angiogenesis. While the efficacy of a model based on cuproptosis-related genes (CRGs) in predicting the prognosis of periphera...

Tao Chang, Yihan Wu, **aodong Niu, Zhiwei Guo, Jiahao Gan, **ang Wang… in Human Genomics (2024)

Article

Notoginsenoside R1 promotes Lgr5⁺ stem cell and epithelium renovation in colitis mice via activating Wnt/β-Catenin signaling

Inflammatory bowel disease (IBD) is characterized by persistent damage to the intestinal barrier and excessive inflammation, leading to increased intestinal permeability. Current treatments of IBD primarily ad...

Zhi-lun Yu, Rui-yang Gao, Cheng Lv, **ao-long Geng… in Acta Pharmacologica Sinica (2024)

Article

Radiofrequency radiation reshapes tumor immune microenvironment into antitumor phenotype in pulmonary metastatic melanoma by inducing active transformation of tumor-infiltrating CD8⁺ T and NK cells

Immunosuppression by the tumor microenvironment is a pivotal factor contributing to tumor progression and immunotherapy resistance. Priming the tumor immune microenvironment (TIME) has emerged as a promising s...

Jia-zheng Jiao, Yang Zhang, Wen-juan Zhang, Min-di He… in Acta Pharmacologica Sinica (2024)

Article

TRIM33 plays a critical role in regulating dendritic cell differentiation and homeostasis by modulating Irf8 and Bcl2l11 transcription

The development of distinct dendritic cell (DC) subsets, namely, plasmacytoid DCs (pDCs) and conventional DC subsets (cDC1s and cDC2s), is controlled by specific transcription factors. IRF8 is essential for th...

**angyi Shen, **aoguang Li, Tao Wu, Tingting Guo… in Cellular & Molecular Immunology (2024)

Article

WZ-3146 acts as a novel small molecule inhibitor of KIF4A to inhibit glioma progression by inducing apoptosis

Glioma is considered the most common primary malignant tumor of the central nervous system. Although traditional treatments have not achieved satisfactory outcomes, recently, targeted therapies for glioma have...

Tao Yan, Qing Jiang, Guangpu Ni, Haofeng Ma, Yun Meng… in Cancer Cell International (2024)

Article

Screening of potential hub genes involved in Kidney Wilms tumor via bioinformatics analysis and experimental validation

Wilms tumor (WT) is the most common pediatric embryonal tumor. Improving patient outcomes requires advances in understanding and targeting the multiple genes and cellular control pathways, but its pathogenesis...

Qiang Zeng, Tingting Liu, Lilu Qin, Chen Wang, Guangbei Peng, Zhong Liu… in BMC Cancer (2024)