30 Result(s)

Article

The Role of the Intestinal Flora and Its Derivatives in Neurocognitive Disorders: A Narrative Review from Surgical Perspective

Perioperative neurocognitive dysfunction is a significant concern for population health, impacting postoperative recovery and increasing the financial burden on patients. With an increasing number of surgical ...

Jian Huang, Tian-Shou Qin, Yun Bo, Yu-** Li, Rong-Sheng Liu… in Molecular Neurobiology (2024)

Article

A Bibliometric Analysis of the Spatial Transcriptomics Literature from 2006 to 2023

In recent years, spatial transcriptomics (ST) research has become a popular field of study and has shown great potential in medicine. However, there are few bibliometric analyses in this field. Thus, in this s...

Shu-Han Zhao, **n-Yu Ji, Guo-Zhen Yuan, Tao Cheng… in Cellular and Molecular Neurobiology (2024)

Article

Knockdown of DJ-1 Exacerbates Neuron Apoptosis Induced by TgCtwh3 through the NF-κB Pathway

Mutations or loss of function of DJ-1 and Toxoplasma gondii (T. gondii) infection has been linked to neurodegenerative diseases, which are often caused by oxidative stress. However, the relationship between DJ-1 ...

Di Yang, Minmin Wu, Nian Zou, Yiru Tang, Qing Tao, Lei Liu… in Molecular Neurobiology (2024)

Article

Correction: m6A-Induced lncRNA MEG3 Promotes Cerebral Ischemia-Reperfusion Injury Via Modulating Oxidative Stress and Mitochondrial Dysfunction by hnRNPA1/Sirt2 Axis

Ling Yao, Pei Peng, Tao Ding, **g Yi, Ji Liang in Molecular Neurobiology (2024)

Article

Correction: Desmoglein-2 Affects Vascular Function in Moyamoya Disease by Interacting with MMP-9 and Influencing PI3K Signaling

Ajun Wang, Nan Li, Nan Zhang, Jian Liu, Tao Yang, Dongxue Li… in Molecular Neurobiology (2024)

Article

Expression of CGRP in the Trigeminal Ganglion and Its Effect on the Polarization of Macrophages in Rats with Temporomandibular Arthritis

Calcitonin gene-related peptide (CGRP) is synthesized and secreted by trigeminal ganglion neurons, and is a key neuropeptide involved in pain and immune regulation. This study investigates the expression of CG...

Junli Tao, **aohui Wang, Jie Xu in Cellular and Molecular Neurobiology (2024)

Article

Desmoglein-2 Affects Vascular Function in Moyamoya Disease by Interacting with MMP-9 and Influencing PI3K Signaling

The pathogenesis and development of Moyamoya disease are still unclear. This study aimed to investigate the effect of desmoglein-2 (DSG2) on Moyamoya disease and determine the inhibitory effect of DSG2 in vasc...

Ajun Wang, Nan Li, Nan Zhang, Jian Liu, Tao Yang, Dongxue Li… in Molecular Neurobiology (2024)

Article

Alisol A Exerts Neuroprotective Effects Against HFD-Induced Pathological Brain Aging via the SIRT3-NF-κB/MAPK Pathway

Chronic consumption of a high-fat diet (HFD) has profound effects on brain aging, which is mainly characterized by cognitive decline, inflammatory responses, and neurovascular damage. Alisol A (AA) is a triter...

Taotao Lu, Linlin Ding, **aoqing Zheng, Yongxu Li, Wei Wei… in Molecular Neurobiology (2024)

Article

CircSKA3 is Associated With the Risk of Extracranial Artery Stenosis and Plaque Instability Among Ischemic Stroke Patients

Circular RNA circSKA3 (spindle and kinetochore-related complex subunit 3) has been identified as a prognostic factor in ischemic stroke. The objective of this study was to investigate the association of circSK...

Ning Zhu, Ziyi Wang, Mingfeng Tao, Yongxin Li… in Cellular and Molecular Neurobiology (2024)

Article

Elabela, a Novel Peptide, Exerts Neuroprotective Effects Against Ischemic Stroke Through the APJ/miR-124-3p/CTDSP1/AKT Pathway

Elabela (ELA), which is the second endogenous peptide ligand of the apelin receptor (APJ) to be discovered, has been widely studied for potential use as a therapeutic peptide. However, its role in ischemic str...

Kang-long Zhang, Shuang-mei Li, **g-yu Hou… in Cellular and Molecular Neurobiology (2023)

Article

Ndufa4 Regulates the Proliferation and Apoptosis of Neurons via miR-145a-5p/Homer1/Ccnd2

The Dandy–Walker malformation (DWM) is characterized by neuron dysregulation in embryonic development; however, the regulatory mechanisms associated with it are unclear. This study aimed to investigate the rol...

Fang Fu, Chen Chen, Kun Du, Lu-shan Li, Ru Li, Ting-ying Lei… in Molecular Neurobiology (2023)

Article

Correction to: Protective Effects of Chinese Herbal Medicine Rhizoma drynariae in Rats After Traumatic Brain Injury and Identification of Active Compound

Wenzhu Wang, Haigang Li, **tao Yu, Michael Hong, **g Zhou… in Molecular Neurobiology (2023)

Article

Transcranial Direct-Current Stimulation Regulates MCT1-PPA-PTEN-LONP1 Signaling to Confer Neuroprotection After Rat Cerebral Ischemia–Reperfusion Injury

Propionic acid (PPA) is a critical metabolite involved in microbial fermentation, which functions to reduce fat production, inhibit inflammation, and reduce serum cholesterol levels. The role of PPA in the con...

**angyi Kong, Wenjie Hu, Yu Cui, **gchen Gao, Xu** Yao… in Molecular Neurobiology (2022)

Article

AIF Overexpression Aggravates Oxidative Stress in Neonatal Male Mice After Hypoxia–Ischemia Injury

There are sex differences in the severity, mechanisms, and outcomes of neonatal hypoxia–ischemia (HI) brain injury, and apoptosis-inducing factor (AIF) may play a critical role in this discrepancy. Based on pr...

Tao Li, Yanyan Sun, Shan Zhang, Yiran Xu, Kenan Li, Cuicui **e… in Molecular Neurobiology (2022)

Article

Cadmium Through Disturbing MTF1-Mediated Metal Response Induced Cerebellar Injury

Cadmium (Cd) is a toxic environmental contaminant, which bio-accumulate in animals through the food chain. Cerebellum is one of the primary target organs for Cd exposure. In this study, we established a chroni...

Shao-Shuai Bi, Milton Talukder, Hai-Tao **, Mei-Wei Lv, **g Ge… in Neurotoxicity Research (2022)

Article

C/EBPβ Participates in Nerve Trauma-Induced TLR7 Upregulation in Primary Sensory Neurons

Nerve trauma-induced toll-like receptor 7 (TLR7) expression level increases in primary sensory neurons in injured dorsal root ganglion (DRG) avails to neuropathic pain, but the reason is still unknown. In the ...

Long He, **g Cao, Bao-Chun Jiang, Jian-Jun Yang, Yuan-**ang Tao… in Molecular Neurobiology (2022)

Article

Cancerous Inhibitor of Protein Phosphatase 2A (CIP2A): Could It Be a Promising Biomarker and Therapeutic Target in Parkinson’s Disease?

Parkinson’s disease (PD) is an incurable neurodegenerative disease characterized by aggregation of pathological alpha-synuclein (α-syn) and loss of dopaminergic neuron in the substantia nigra. Inhibition of ph...

Sijia Yin, Chao Han, Yun **a, Fang Wan, Junjie Hu, Liang Kou… in Molecular Neurobiology (2022)

Article

Autophagy Inhibition Reduces Irradiation-Induced Subcortical White Matter Injury Not by Reducing Inflammation, but by Increasing Mitochondrial Fusion and Inhibiting Mitochondrial Fission

Radiotherapy is an effective tool in the treatment of malignant brain tumors, but irradiation-induced late-onset toxicity remains a major problem. The purpose of this study was to investigate if genetic inhibi...

Yafeng Wang, Yiran Xu, Kai Zhou, Shan Zhang, Yong Wang, Tao Li… in Molecular Neurobiology (2022)

Article

Role of the PD‐1/PD‐L1 Signaling in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis: Recent Insights and Future Directions

Multiple sclerosis (MS) is an autoimmunity-related chronic demyelination disease of the central nervous system (CNS), causing young disability. Currently, highly specific immunotherapies for MS are still lacki...

Yan Mi, **ming Han, Jie Zhu, Tao ** in Molecular Neurobiology (2021)

Article

Targeted sequencing and integrative analysis to prioritize candidate genes in neurodevelopmental disorders

Neurodevelopmental disorders (NDDs) are a group of diseases characterized by high heterogeneity and frequently co-occurring symptoms. The mutational spectrum in patients with NDDs is largely incomplete. Here, ...

Yi Zhang, Tao Wang, Yan Wang, Kun **a, **chen Li, Zhongsheng Sun in Molecular Neurobiology (2021)