100 Result(s)

Article

Uncovering the role of ferroptosis in Bietti crystalline dystrophy and potential therapeutic strategies

Bietti crystalline dystrophy (BCD) is an inherited retinal degeneration disease caused by mutations in the CYP4V2 gene. Currently, there is no clinical therapy approach available for BCD patients. Previous resear...

Chang Shen, Qianjie Yang, Kuangqi Chen, Huiling Ma… in Cell Communication and Signaling (2024)

Article

Influence of thickness and strength on plastic instability in tailored steel structures

A mathematical model was intricately devised to explore the influence of continuous variations in thickness and mechanical properties on the performance of tailor rolled blanks (TRB) and tailor rolled tubes (T...

Rihuan Lu, Shoudong Chen, **aogong Wang, Meihui Li, Sijia Zhang… in Scientific Reports (2024)

Article

Neoadjuvant chemotherapy with or without camrelizumab in resectable esophageal squamous cell carcinoma: the randomized phase 3 ESCORT-NEO/NCCES01 trial

Recent single-arm studies involving neoadjuvant camrelizumab, a PD-1 inhibitor, plus chemotherapy for resectable locally advanced esophageal squamous cell carcinoma (LA-ESCC) have shown promising results. This...

Jianjun Qin, Liyan Xue, Anlin Hao, **aofeng Guo, Tao Jiang, Yunfeng Ni… in Nature Medicine (2024)

Article

Evaluation of agricultural non-point source pollution using an in-situ and automated photochemical flow analysis system

Off-line leachate collection from agricultural landscapes cannot guarantee precise evaluation of agricultural non-point source (ANPS) due to geospatial variations, time, and transportation from the field to th...

Yongqi Chen, Muhammad Awais, Junfeng Wu, Zhenfeng Li… in Scientific Reports (2024)

Article

Author Correction: RNA polymerase II pausing regulates chromatin organization in erythrocytes

Andrés Penagos-Puig, Sherlyn Claudio-Galeana… in Nature Structural & Molecular Biology (2024)

Article

Genome-wide DNA methylation-analysis of blastic plasmacytoid dendritic cell neoplasm identifies distinct molecular features

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) constitutes a rare and aggressive malignancy originating from plasmacytoid dendritic cells (pDCs) with a primarily cutaneous tropism followed by disseminati...

Axel Künstner, Julian Schwarting, Hanno M. Witte, Pengwei **ng… in Leukemia (2024)

Article

Diamond-Like Carbon Depositing on the Surface of Polylactide Membrane for Prevention of Adhesion Formation During Tendon Repair

Article

Bone-derived PDGF-BB enhances hippocampal non-specific transcytosis through microglia-endothelial crosstalk in HFD-induced metabolic syndrome

It is well known that high-fat diet (HFD)-induced metabolic syndrome plays a crucial role in cognitive decline and brain-blood barrier (BBB) breakdown. However, whether the bone-brain axis participates in this...

Guanqiao Liu, Wen Shu, Yingqi Chen, Yong Fu, Shuai Fang… in Journal of Neuroinflammation (2024)

Article

Empowering high-dimensional optical fiber communications with integrated photonic processors

Mode-division multiplexing (MDM) in optical fibers enables multichannel capabilities for various applications, including data transmission, quantum networks, imaging, and sensing. However, high-dimensional opt...

Kaihang Lu, Zengqi Chen, Hao Chen, Wu Zhou, Zunyue Zhang… in Nature Communications (2024)

Article

Tumor immune dysfunction and exclusion subtypes in bladder cancer and pan-cancer: a novel molecular subty** strategy and immunotherapeutic prediction model

Molecular subty** is expected to enable precise treatment. However, reliable subty** strategies for clinical application remains defective and controversial. Given the significance of tumor immune dysfunct...

Kun Zheng, Youlong Hai, Hongqi Chen, Yukun Zhang… in Journal of Translational Medicine (2024)

Article

Methylation in cornea and corneal diseases: a systematic review

Corneal diseases are among the primary causes of blindness and vision loss worldwide. However, the pathogenesis of corneal diseases remains elusive, and diagnostic and therapeutic tools are limited. Thus, iden...

Yutong **a, Kuangqi Chen, Qianjie Yang, Zhitong Chen, Le **… in Cell Death Discovery (2024)

Article

Study of the mandibular canal and its surrounding canals by multi-view cone-beam computed tomography

To determine the mandibular anatomical structures by observing cone-beam computed tomography (CBCT) from multiple angles.

Yingqi Chen, Qianting Liao, Yuexia Wu, Rui He, Nanxiang Zhang… in Insights into Imaging (2024)

Article

Knockdown of NCAPD3 inhibits the tumorigenesis of non-small cell lung cancer by regulation of the PI3K/Akt pathway

Accumulating evidence indicates that aberrant non-SMC condensin II complex subunit D3 (NCAPD3) is associated with carcinogenesis of various cancers. Nevertheless, the biological role of NCAPD3 in the pathogene...

Fan Yang, Yunfeng Zheng, Qiong Luo, Suyun Zhang, Sheng Yang, **angqi Chen in BMC Cancer (2024)

Article

Association of interleukin-6, ferritin, and lactate dehydrogenase with venous thromboembolism in COVID-19: a systematic review and meta-analysis

Coronavirus disease 2019 (COVID-19) is frequntly accompanied by venous thromboembolism (VTE), and its mechanism may be related to the abnormal inflammation and immune status of COVID-19 patients. It has been p...

Haiyu Liu, Ning**g Guo, Qixian Zheng, Qianyuan Zhang… in BMC Infectious Diseases (2024)

Article

Preconception folic acid supplementation for the prevention of birth defects: a prospective, population-based cohort study in mainland China

Folic acid supplementation is recommended for reducing the risk of birth defects. We aimed to assess the protective association of periconception folic acid supplements with birth defects in real-world setting.

Qiongjie Zhou, Guiying Dong, Qiaomei Wang, Hai** Shen… in BMC Pregnancy and Childbirth (2024)

Article

Genomic characterization and immunotherapy for microsatellite instability-high in cholangiocarcinoma

Microsatellite instability-high (MSI-H) is a unique genomic status in many cancers. However, its role in the genomic features and immunotherapy in cholangiocarcinoma (CCA) is unclear. This study aimed to syste...

Xu Yang, Baofeng Lian, Nan Zhang, Junyu Long, Yiran Li, **gnan Xue… in BMC Medicine (2024)

Article

In-depth metaproteomics analysis of tongue coating for gastric cancer: a multicenter diagnostic research study

Our previous study revealed marked differences in tongue images between individuals with gastric cancer and those without gastric cancer. However, the biological mechanism of tongue images as a disease indicat...

Jiahui Chen, Yingying Sun, Jie Li, Mengge Lyu, Li Yuan, Jiancheng Sun… in Microbiome (2024)

Article

Baicalin inhibits IL-1β-induced ferroptosis in human osteoarthritis chondrocytes by activating Nrf-2 signaling pathway

Osteoarthritis (OA) is a common degenerative disease involving articular cartilage, in which ferroptosis of chondrocytes plays an important role. Baicalin (BAI) exerts regulatory effects in a wide range of ort...

Jiuxiang Liu, Hao Zhou, Jiangqi Chen… in Journal of Orthopaedic Surgery and Research (2024)

Article

Retraction Note: Long noncoding RNA HEIH depletion depresses esophageal carcinoma cell progression by upregulating microRNA-185 and downregulating KLK5

Bing Wang, Xuezhi Hao, **ngkai Li, Yicheng Liang, Fang Li, Kun Yang… in Cell Death & Disease (2023)

Article

Correction: Progress and challenges in energy storage and utilization via ammonia

Chongqi Chen, Yanliang Zhou, Huihuang Fang, **aobo Peng… in Surface Science and Technology (2023)