![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
An epigenome-wide association study of waist circumference in Chinese monozygotic twins
Central obesity poses significant health risks because it increases susceptibility to multiple chronic diseases. Epigenetic features such as DNA methylation may be associated with specific obesity traits, whic...
-
Article
Open AccessIdentification of key DNA methylation changes on fasting plasma glucose: a genome-wide DNA methylation analysis in Chinese monozygotic twins
Elevated fasting plasma glucose (FPG) levels can increase morbidity and mortality even when it is below the diagnostic threshold of type 2 diabetes mellitus (T2DM). We conducted a genome-wide DNA methylation a...
-
Article
Open AccessEpigenome-wide association study in Chinese monozygotic twins identifies DNA methylation loci associated with blood pressure
Hypertension is a crucial risk factor for develo** cardiovascular disease and reducing life expectancy. We aimed to detect DNA methylation (DNAm) variants potentially related to systolic blood pressure (SBP)...
-
Article
Open AccessMultivariate genome-wide association study of depression, cognition, and memory phenotypes and validation analysis identify 12 cross-ethnic variants
To date, little is known about the pleiotropic genetic variants among depression, cognition, and memory. The current research aimed to identify the potential pleiotropic single nucleotide polymorphisms (SNPs),...
-
Article
Open AccessNonreproductive effects are more important than reproductive effects in a host feeding parasitoid
When female host feeding parasitoids encounter a potential host, they face a complicated trade-off between either laying an egg for investing in current reproduction or feeding on or killing the host for futur...
-
Article
Open AccessAssociation between dairy consumption and ischemic heart disease among Chinese adults: a prospective study in Qingdao
Previous studies linking dairy consumption with ischemic heart disease (IHD) are almost from western countries, with little from China. The present study was to explore the relationship between dairy consumpti...
-
Article
Open AccessGenome-wide DNA methylation analysis of pulmonary function in middle and old-aged Chinese monozygotic twins
Previous studies have determined the epigenetic association between DNA methylation and pulmonary function among various ethnics, whereas this association is largely unknown in Chinese adults. Thus, we aimed t...
-
Article
Open AccessGenome-wide DNA methylation and gene expression analyses in monozygotic twins identify potential biomarkers of depression
Depression is currently the leading cause of disability around the world. We conducted an epigenome-wide association study (EWAS) in a sample of 58 depression score-discordant monozygotic twin pairs, aiming to...
-
Article
Open AccessHeritability and genome-wide association analyses of fasting plasma glucose in Chinese adult twins
Currently, diabetes has become one of the leading causes of death worldwide. Fasting plasma glucose (FPG) levels that are higher than optimal, even if below the diagnostic threshold of diabetes, can also lead ...
-
Article
A genome-wide association study of cognitive function in Chinese adult twins
Multiple loci or genes have been identified using genome-wide association studies mainly in western countries but with inconsistent results. No similar studies have been conducted in the world’s largest and ra...
-
Article
Open AccessPregnancy, pregnancy loss, and the risk of cardiovascular disease in Chinese women: findings from the China Kadoorie Biobank
Pregnancy and pregnancy loss may be linked to cardiovascular disease (CVD). However, the evidence is still inconsistent, especially in East Asians, whose reproductive patterns differ importantly from those in ...