7 Result(s)
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Article
**anghao Wu
Chemistry
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Article
Open AccessNovel inhalation therapy in pulmonary fibrosis: principles, applications and prospects
Pulmonary fibrosis (PF) threatens millions of people worldwide with its irreversible progression. Although the underlying pathogenesis of PF is not fully understood, there is evidence to suggest that the disea...
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Open AccessTraditional Chinese medicine inspired dual-drugs loaded inhalable nano-therapeutics alleviated idiopathic pulmonary fibrosis by targeting early inflammation and late fibrosis
Idiopathic pulmonary fibrosis (IPF) is a highly debilitating and fatal chronic lung disease that is difficult to cure clinically. IPF is characterized by a gradual decline in lung function, which leads to resp...
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Open AccessImpaired autophagy-accelerated senescence of alveolar type II epithelial cells drives pulmonary fibrosis induced by single-walled carbon nanotubes
The rapid increase in production and application of carbon nanotubes (CNTs) has led to wide public concerns in their potential risks to human health. Single-walled CNTs (SWCNTs), as an extensively applied type...
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Open AccessNAMPT encapsulated by extracellular vesicles from young adipose-derived mesenchymal stem cells treated tendinopathy in a “One-Stone-Two-Birds” manner
Tendinopathy is the leading sports-related injury and will cause severe weakness and tenderness. Effective therapy for tendinopathy remains limited, and extracellular vesicles (EVs) derived from adipose tissue...
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Natural killer cell-derived extracellular vesicle significantly enhanced adoptive T cell therapy against solid tumors via versatilely immunomodulatory coordination
Insufficient tumor tropism, MHC class I molecules (MHC-I) defects of tumor cells, and immunosuppressive tumor micro-environment (TME) seriously imperil the efficacy of adoptive T cell therapy on solid tumors. ...
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Open AccessEliminating acetate formation improves citramalate production by metabolically engineered Escherichia coli
Citramalate, a chemical precursor to the industrially important methacrylic acid (MAA), can be synthesized using Escherichia coli overexpressing citramalate synthase (cimA gene). Deletion of gltA encoding citrate...
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Catalytic epoxidation of fatty acid methyl esters by modified metalloporphyrins with variable metals and electron-donating substituents
The catalytic efficiency of modified tetraphenylporphyrins with various metals (Mn, Fe, Co, Ni and Zn) and different electron-donating substituents (–OCH3, –OH, –N(CH3)2, –SO3Na) at the phenyl para-positions usin...
