64 Result(s)
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Article
**ang-yue Wang
Science, Humanities and Social Sciences, multidisciplinary
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Article
Acidic Proteins of Cellular Nuclei
AN alkali-soluble protein fraction, obtained from calf thymus nuclei, was reported by Mayer and Gulick1. Upon addition of acid to the alkaline solution, precipitation of this fraction occurred at about pH 6. Sted...
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Free Amino-acids of Isolated Calf Thymus Nuclei
CALF thymus nuclei prepared by the sucrose–calcium chloride method of Allfrey et al.1 are remarkably biochemically active, as judged by the incorporation of labelled amino-acids into the nuclear proteins1,2. Such...
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Infra-nuclear Distribution of Transaminases
IT has previously been shown1 that isolated calf thymus nuclei prepared by the sucrose-CaCl2 procedure2 contain a free amino-acid pool. Of the free amino-acids, glutamic acid represents about 40 per cent. The pre...
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Open AccessUnique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing
Leptospirosis is a widely spread disease of global concern. Infection causes flu-like episodes with frequent severe renal and hepatic damage, such as haemorrhage and jaundice. In more severe cases, massive pul...
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Open AccessMetagenomic analysis of the pinewood nematode microbiome reveals a symbiotic relationship critical for xenobiotics degradation
Our recent research revealed that pinewood nematode (PWN) possesses few genes encoding enzymes for degrading α-pinene, which is the main compound in pine resin. In this study, we examined the role of PWN micro...
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IKKα restoration via EZH2 suppression induces nasopharyngeal carcinoma differentiation
Lack of cellular differentiation is a key feature of nasopharyngeal carcinoma (NPC), but it also presents as a unique opportunity for intervention by differentiation therapy. Here using RNA-seq profiling analy...
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Open AccessAnalysis of phytoplasma-responsive sRNAs provide insight into the pathogenic mechanisms of mulberry yellow dwarf disease
The yellow dwarf disease associated with phytoplasmas is one of the most devastating diseases of mulberry and the pathogenesis involved in the disease is poorly understood. To analyze the molecular mechanisms ...
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Open AccessbFGF regulates autophagy and ubiquitinated protein accumulation induced by myocardial ischemia/reperfusion via the activation of the PI3K/Akt/mTOR pathway
Autophagy is involved in the development and/or progression of many diseases, including myocardial ischemia/reperfusion (I/R). In this study, we hypothesized a protective role of basic fibroblast growth factor...
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Open AccessGenetic diversity and evolutionary dynamics of Ebola virus in Sierra Leone
The genome sequences of 175 Ebola virus from five districts in Sierra Leone, collected during September–November 2014, show that the rate of virus evolution seems to be similar to that observed during previous...
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Open AccessFunctional and structural properties of a novel cellulosome-like multienzyme complex: efficient glycoside hydrolysis of water-insoluble 7-xylosyl-10-deacetylpaclitaxel
Cellulosome is a kind of multienzyme complex that displays high activity, selectivity and stability. Here, we report a novel, non-cellulolytic, cellulosome-like multienzyme complex that produced by the Cellulosim...
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Open AccessGossypium barbadense genome sequence provides insight into the evolution of extra-long staple fiber and specialized metabolites
Of the two cultivated species of allopolyploid cotton, Gossypium barbadense produces extra-long fibers for the production of superior textiles. We sequenced its genome (AD)2 and performed a comparative analysis. ...
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Erratum: Genetic diversity and evolutionary dynamics of Ebola virus in Sierra Leone
Nature 524, 93–96 (2015); doi:10.1038/nature14490 This Letter should have contained an associated Creative Commons statement in the Author Information section. In addition, the Fig. 3c legend should have state...
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Open AccessFinite-key security analyses on passive decoy-state QKD protocols with different unstable sources
In quantum communication, passive decoy-state QKD protocols can eliminate many side channels, but the protocols without any finite-key analyses are not suitable for in practice. The finite-key securities of pa...
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Open AccessSystolic aortic pressure-time area is a useful index describing arterial wave properties in rats with diabetes
The accurate measurement of arterial wave properties in terms of arterial wave transit time (τw) and wave reflection factor (Rf) requires simultaneous records of aortic pressure and flow signals. However, in clin...
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Open AccessRole of Berberine in the Treatment of Methicillin-Resistant Staphylococcus aureus Infections
Berberine is an isoquinoline alkaloid widely used in the treatment of microbial infections. Recent studies have shown that berberine can enhance the inhibitory efficacy of antibiotics against clinical multi-dr...
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Open AccessLarge-scale rewiring of innate immunity circuitry and microRNA regulation during initial rice blast infection
Rice blast is a recurrent fungal disease, and resistance to fungal infection is a complex trait. Therefore, a comprehensive examination of rice transcriptome and its variation during fungal infection is necess...
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Open AccessPenicimenolides A-F, Resorcylic Acid Lactones from Penicillium sp., isolated from the Rhizosphere Soil of Panax notoginseng
Five new 12-membered resorcylic acid lactone derivatives, penicimenolides A-E (1–5), one new ring-opened resorcylic acid lactone derivative penicimenolide F (6) and six known biogenetically related derivatives (7...
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Open AccessCurcumin ameliorates neuropathic pain by down-regulating spinal IL-1β via suppressing astroglial NALP1 inflammasome and JAK2-STAT3 signalling
Curcumin has been shown to possess strong anti-inflammatory activity in many diseases. It has been demonstrated that the janus kinase 2 (JAK2)-signal transducer and activator of transcription 3 (STAT3) cascade...
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Open AccessCombining Exosomes Derived from Immature DCs with Donor Antigen-Specific Treg Cells Induces Tolerance in a Rat Liver Allograft Model
Allograft tolerance is the ultimate goal in the field of transplantation immunology. Immature dendritic cells (imDCs) play an important role in establishing tolerance but have limitations, including potential ...
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Open AccessCharacteristics of CpG Islands and their quasispecies of full-length hepatitis B virus genomes from patients at different phases of infection
CpG islands in hepatitis B virus (HBV) genome are potential targets for methylation mediated gene silencing, and may be involved in the pathogenesis of HBV infection. To date, their characteristics in HBV quas...
