19 Result(s)

Article

Doxorubicin resistant cancer cells activate myeloid-derived suppressor cells by releasing PGE₂

Chemotherapies often induce drug-resistance in cancer cells and simultaneously stimulate proliferation and activation of Myeloid-Derived Suppressor Cells (MDSCs) to inhibit anti-tumor T cells, thus result in p...

Yuan Rong, Chun-Hui Yuan, Zhen Qu, Hu Zhou, Qing Guan, Na Yang… in Scientific Reports (2016)

Article

A Novel Protective Function of 5-Methoxytryptophan in Vascular Injury

5-Methoxytryptophan (5-MTP), a 5-methoxyindole metabolite of tryptophan metabolism, was recently shown to suppress inflammatory mediator-induced cancer cell proliferation and migration. However, the role of 5-...

Yen-Chun Ho, Meng-Ling Wu, Chen-Hsuan Su, Chung-Huang Chen… in Scientific Reports (2016)

Article

Discovery, screening and evaluation of a plasma biomarker panel for subjects with psychological suboptimal health state using ¹H-NMR-based metabolomics profiles

Individuals in the state of psychological suboptimal health keep increasing, only scales and questionnaires were used to diagnose in clinic under current conditions, and symptoms of high reliability and accura...

Jun-sheng Tian, **ao-tao **a, Yan-fei Wu, Lei Zhao, Huan **ang… in Scientific Reports (2016)

Article

Main Effects of Diagnoses, Brain Regions, and their Interaction Effects for Cerebral Metabolites in Bipolar and Unipolar Depressive Disorders

Previous studies suggested patients with bipolar depressive disorder (BDd) or unipolar depressive disorder (UDd) have cerebral metabolites abnormalities. These abnormalities may stem from multiple sub-regions ...

Hai-Zhu Tan, Hui Li, Chen-Feng Liu, Ji-Tian Guan, **ao-Bo Guo… in Scientific Reports (2016)

Article

Herb pair Danggui-Honghua: mechanisms underlying blood stasis syndrome by system pharmacology approach

Herb pair Danggui-Honghua has been frequently used for treatment of blood stasis syndrome (BSS) in China, one of the most common clinical pathological syndromes in traditional Chinese medicine (TCM). However, ...

Shi-Jun Yue, Lan-Ting **n, Ya-Chu Fan, Shu-Jiao Li, Yu-** Tang… in Scientific Reports (2017)

Article

Overexpression of ovine AANAT and HIOMT genes in switchgrass leads to improved growth performance and salt-tolerance

Melatonin is a well-known bioactive molecule with an array of health-promoting properties. Here, we detected the physiological function of melatonin in transgenic switchgrass overexpressing the homologous shee...

Yan-Hua Huang, Si-Jia Liu, Shan Yuan, Cong Guan, Dan-Yang Tian… in Scientific Reports (2017)

Article

Uncovering the anticancer mechanism of Compound Kushen Injection against HCC by integrating quantitative analysis, network analysis and experimental validation

Compound Kushen Injection (CKI) is a Traditional Chinese Medicine (TCM) preparation that has been clinically used in China to treat various types of solid tumours. Although several studies have revealed that C...

Li Gao, Ke-xin Wang, Yu-zhi Zhou, Jian-song Fang, Xue-mei Qin… in Scientific Reports (2018)

Article

Giant energy density and high efficiency achieved in bismuth ferrite-based film capacitors via domain engineering

Develo** high-performance film dielectrics for capacitive energy storage has been a great challenge for modern electrical devices. Despite good results obtained in lead titanate-based dielectrics, lead-free ...

Hao Pan, **g Ma, Ji Ma, Qinghua Zhang, **aozhi Liu, Bo Guan… in Nature Communications (2018)

Article

N⁶-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis

Circular RNAs (circRNAs) have been implicated in cancer progression through largely unknown mechanisms. Herein, we identify an N⁶-methyladenosine (m⁶A) modified circRNA, circNSUN2, frequently upregulated in tumor...

Ri-**n Chen, **n Chen, Liang-** **a, Jia-**ng Zhang… in Nature Communications (2019)

Article

Universal mechanical exfoliation of large-area 2D crystals

Two-dimensional materials provide extraordinary opportunities for exploring phenomena arising in atomically thin crystals. Beginning with the first isolation of graphene, mechanical exfoliation has been a key ...

Yuan Huang, Yu-Hao Pan, Rong Yang, Li-Hong Bao, Lei Meng… in Nature Communications (2020)

Article

Author Correction: Universal mechanical exfoliation of large-area 2D crystals

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Yuan Huang, Yu-Hao Pan, Rong Yang, Li-Hong Bao, Lei Meng… in Nature Communications (2020)

Article

Identifying SARS-CoV-2-related coronaviruses in Malayan pangolins

The ongoing outbreak of viral pneumonia in China and across the world is associated with a new coronavirus, SARS-CoV-2¹. This outbreak has been tentatively associated with a seafood market in Wuhan, China, where ...

Tommy Tsan-Yuk Lam, Na Jia, Ya-Wei Zhang, Marcus Ho-Hin Shum, Jia-Fu Jiang… in Nature (2020)

Article

Methylamine-assisted growth of uniaxial-oriented perovskite thin films with millimeter-sized grains

Defects from grain interiors and boundaries of perovskite films cause significant nonradiative recombination energy loss, and thus perovskite films with controlled crystallinity and large grains is critical fo...

Haochen Fan, Fengzhu Li, Pengcheng Wang, Zhenkun Gu, **-Hua Huang… in Nature Communications (2020)

Article

Population-scale peach genome analyses unravel selection patterns and biochemical basis underlying fruit flavor

A narrow genetic basis in modern cultivars and strong linkage disequilibrium in peach (Prunus persica) has restricted resolution power for association studies in this model fruit species, thereby limiting our und...

Yang Yu, Jiantao Guan, Yaoguang Xu, Fei Ren, Zhengquan Zhang… in Nature Communications (2021)

Article

Long noncoding RNA BS-DRL1 modulates the DNA damage response and genome stability by interacting with HMGB1 in neurons

Long noncoding RNAs (lncRNAs) are known to regulate DNA damage response (DDR) and genome stability in proliferative cells. However, it remains unknown whether lncRNAs are involved in these vital biological pro...

Min-Min Lou, **ao-Qiang Tang, Guang-Ming Wang, Jia He, Fang Luo… in Nature Communications (2021)

Article

Comparison of adenoma detection in different colorectal segments between deep-sedated and unsedated colonoscopy

To investigate if deep-sedated colonoscopy affects adenoma detection in certain colorectal segment. Review of colonoscopy reports, electronic images and medical records of individuals underwent screening colon...

Yue Sui, Qing Wang, Hai-Hua Chen, Jun-Hui Lu, Qing Wen… in Scientific Reports (2022)

Article

Cellular differentiation into hyphae and spores in halophilic archaea

Several groups of bacteria have complex life cycles involving cellular differentiation and multicellular structures. For example, actinobacteria of the genus Streptomyces form multicellular vegetative hyphae, aer...

Shu-Kun Tang, **ao-Yang Zhi, Yao Zhang, Kira S. Makarova… in Nature Communications (2023)

Article

Addendum: Cellular differentiation into hyphae and spores in halophilic archaea

Shu-Kun Tang, **ao-Yang Zhi, Yao Zhang, Kira S. Makarova… in Nature Communications (2024)