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Article
Open AccessAn improved genome assembly of Chrysanthemum nankingense reveals expansion and functional diversification of terpene synthase gene family
Terpenes are important components of plant aromas, and terpene synthases (TPSs) are the key enzymes driving terpene diversification. In this study, we characterized the volatile terpenes in five different Chrysan...
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Article
Open AccessConstraining primordial black holes as dark matter using AMS-02 data
Primordial black holes (PBHs) are the plausible candidates for the cosmological dark matter. Theoretically, PBHs with masses $$M_{\textrm{PBH}...
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Article
Open AccessRealization of monolayer ZrTe5 topological insulators with wide band gaps
Two-dimensional topological insulators hosting the quantum spin Hall effect have application potential in dissipationless electronics. To observe the quantum spin Hall effect at elevated temperatures, a wide b...
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Article
Open AccessSphingosine d18:1 promotes nonalcoholic steatohepatitis by inhibiting macrophage HIF-2α
Non-alcoholic steatohepatitis (NASH) is a severe type of the non-alcoholic fatty liver disease (NAFLD). NASH is a growing global health concern due to its increasing morbidity, lack of well-defined biomarkers ...
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Article
Open AccessFOXP4-mediated induction of PTK7 activates the Wnt/β-catenin pathway and promotes ovarian cancer development
Ovarian cancer (OV) poses a significant challenge in clinical settings due to its difficulty in early diagnosis and treatment resistance. FOXP4, belonging to the FOXP subfamily, plays a pivotal role in various...
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Article
Open AccessSystematic investigation of the material basis, effectiveness and safety of Thesium chinense Turcz. and its preparation Bairui Granules against lung inflammation
Thesium chinense Turcz. (Named as Bai Rui Cao in Chinese) and its preparations (e.g., Bairui Granules) have been used to treat inflammatory diseases, such as acute mastitis, lobar pneumonia, tonsillitis, coronavi...
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Article
Open AccessSpecific convulsions and brain damage in children hospitalized for Omicron BA.5 infection: an observational study using two cohorts
SARS-CoV-2 continues to mutate over time, and reports on children infected with Omicron BA.5 are limited. We aimed to analyze the specific symptoms of Omicron-infected children and to improve patient care.
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Article
Open AccessNanocomposite magnetic hydrogel with dual anisotropic properties induces osteogenesis through the NOTCH-dependent pathways
Physical factors in the cellular microenvironment have critical effects on stem cell differentiation. The utilization of physical factors to promote the osteogenic differentiation of stem cells has been establ...
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Article
Open AccessAssociation of adverse childhood experiences with anemia in older Chinese: Guangzhou Biobank Cohort Study
To examine the association of adverse childhood experiences (ACEs) with anemia among older people. 24,116 participants aged 50 years or above were recruited. Multivariable linear and logistic regression was us...
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Article
Open AccessAAA237, an SKP2 inhibitor, suppresses glioblastoma by inducing BNIP3-dependent autophagy through the mTOR pathway
Glioblastoma (GBM) is the most common brain tumor with the worst prognosis. Temozolomide is the only first-line drug for GBM. Unfortunately, the resistance issue is a classic problem. Therefore, it is essentia...
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Article
Open AccessDe novo Phased Genome Assembly, Annotation and Population Genoty** of Alectoris Chukar
The Alectoris Chukar (chukar) is the most geographically widespread partridge species in the world, demonstrating exceptional adaptability to diverse ecological environments. However, the scarcity of genetic reso...
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Article
Open AccessElectron scale coherent structure as micro accelerator in the Earth’s magnetosheath
Turbulent energy dissipation is a fundamental process in plasma physics that has not been settled. It is generally believed that the turbulent energy is dissipated at electron scales leading to electron energi...
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Article
Open AccessMolecular sensitised probe for amino acid recognition within peptide sequences
The combination of low-temperature scanning tunnelling microscopy with a mass-selective electro-spray ion-beam deposition established the investigation of large biomolecules at nanometer and sub-nanometer scal...
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Article
Open AccessAssociation of fish and meat consumption with non-alcoholic fatty liver disease: Guangzhou Biobank Cohort Study
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease. Unhealthy dietary habit is one of major risk factors of NAFLD. However, the associations between specific types of fish and m...
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Article
Open AccessIdentification and validation of candidate clinical signatures of apolipoprotein L isoforms in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is a lethal malignancy worldwide with an increasing number of new cases each year. Apolipoprotein (APOL) isoforms have been explored for their associations with HCC.The GSE14520 ...
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Article
Open AccessSearch for pair production of third-generation leptoquarks decaying into a bottom quark and a \(\tau \) -lepton with the ATLAS detector
A search for pair-produced scalar or vector leptoquarks decaying into a b-quark and a \(\tau \) τ ...
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Article
Open AccessSearch for single vector-like B quark production and decay via B → bH( \( b\overline{b} \) ) in pp collisions at \( \sqrt{s} \) = 13 TeV with the ATLAS detector
A search is presented for single production of a vector-like B quark decaying into a Standard Model b-quark and a Standard Model Higgs boson, which decays into a
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Article
Open AccessSearch for direct production of winos and higgsinos in events with two same-charge leptons or three leptons in pp collision data at \( \sqrt{s} \) = 13 TeV with the ATLAS detector
A search for supersymmetry targeting the direct production of winos and higgsinos is conducted in final states with either two leptons (e or μ) with the same electric charge, or three leptons. The analysis uses 1...
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Article
Open AccessLuminosity determination in pp collisions at \(\sqrt{s}=13\) TeV using the ATLAS detector at the LHC
The luminosity determination for the ATLAS detector at the LHC during Run 2 is presented, with pp collisions at a centre-of-mass energy $$\sqr...
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Article
Open AccessMeasurements of multijet event isotropies using optimal transport with the ATLAS detector
A measurement of novel event shapes quantifying the isotropy of collider events is performed in 140 fb−1 of proton-proton collisions with ...
