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943 Result(s)
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Article
Sodium methitural: a clinical study
The properties of methitural with and without premedication have been compared in a series of patients m physical status I and II and of comparable age, height and weight, undergoing minor gynaecological proce...
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Article
Sodium methohexital: a clinical study
Metliohexital is the only intravenous anaesthetic agent tested by us so far which combines shorter action with a higher potency than thiopental. If dose per minute of anaesthesia for a standard procedure is ta...
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A clinical comparison of sodium thiopental (pentothal®), sodium methitural (neraval®), sodium buthalitone (transithal®), and sodium hexobarbital (evipal®)
The claim that some of the newer barbiturates have a shorter duration than older agents has not been borne out by the present investigation in regard to thiopental, but is true in regard to sodium hexobarbital...
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Article
Methoxyflurane (penthrane): a laboratory and clinical study
Methoxyflurane is a new fluorinated and chlorinated saturated asymmetrical ether whose outstanding physical properties are an unusually high boiling point and the fact that it is non-flammable in anaesthetic c...
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Anaesthetic considerations for carotid thrombo-endarterectomy
Patients presenting for carotid thrombo-endarterectomy have precarious brain perfusion. The anaesthetic approach must not be detrimental to adequate cerebral blood flow. Systemic arterial blood pressure must b...
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A clinical appraisal of the adequacy of brain circulation during anaesthesia (with particular reference to carotid thromboendarterectomy)
Studies in 30 patients (out of 100) having carotid thromboendarterectomy are described.
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The validity of using internal jugular ...
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Article
Anaphylaxis to thiopentone: A case report
A case of anaphylaxis to thiopentone is reported and its immediate treatment with epinephrine is emphasized. Other reported cases of allergic reaction to thiopentone and to muscle relaxants are reviewed. There...
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Article
Comparison of adipose glycerol kinase of hyperglycemic obese mice and lean litter-mates
Glycerol kinase activity found in the epididymal adipose tissue of lean litter-mates of hyperglycemic obese mice exhibits two distinct Km values. The Km(s) obtained graphically by a Hoftsee plot are 40 and 637 μm
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Article
Hypoxic gas mixtures delivered by anaesthetic machines equipped with a downstream oxygen flowmeter
The oxygen concentration of fresh gas mixtures delivered to a Bain circuit by a Boyle’s anaesthetic machine equipped with leaking oxygen flowmeters was measured at the common gas outlet during free flow and du...
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Article
Response of white adipocyte of mouse and rabbit to catecholamines and ACTH
Hormone stimulated lipolysis of mouse and rabbit adipocytes as measured by both free fatty acid and glycerol release, is proportionally elevated with increase in the adipocyte cAMP level up to 1 nmole/g. The c...
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Article
Response of white adipocyte of mouse and rabbit to catecholamines and ACTH
Using (−)-[3H]-dihydroalprenolol ([3H]-DHA) and [3H]-norepinephrine ([3H]-NE) as probes, adrenoreceptors in mouse and rabbit adipocyte plasma membranes were studied and compared. The binding of either radioligand...
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Article
Response of white adipocyte of mouse and rabbit to catecholamines and ACTH
The isolated intact white adipocyte of the Swiss mouse responds to both ACTH and catecholamines by an elevation of cAMP levels and an increase in lipolysis. However, in the isolated plasma membrane of the mous...
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Article
Anaesthetic problems associated with the treatment of cardiovascular disease: I. digitalis toxicity
Digitalis intoxication is still a common clinical problem affecting a fifth to a quarter of all digitalized patients. In the surgical patients there are many factors - including fluid, electrolyte and acid-bas...
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Article
Anaesthetic problems associated with the treatment of cardiovascular disease: II. beta-adrenergic antagonists
There are a number of beta-adrenergic antagonists available for general clinical use. The pharmacological action of these agents in patients with ischaemic heart disease and hypertensive cardiovascular disease...
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Article
Excessive requirement for heparin during cardiac surgery
A case of excessive heparin requirement during cardiopulmonary bypass is reported. A patient with sepsis secondary to a myocardial abscess required 13.5 mg . kg-1of heparin to increase his activated coagulation t...
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Cancer, chemotherapy and anaesthesia
Cancer patients coming to operation can suffer from multiple systenuc problems which may complicate the anaesthetic management. Interactions between anaesthetics and cytotoxic agents can occur. Patients may ha...
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Sleep apnoea syndrome and anaesthesia
The sleep apnoea syndrome is reviewed, defined, and classified. Particular emphasis is placed on the identification of a patient population that is prone to sleep apnoea and the diseases and syndromes that are...
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Article
Anaesthetic problems associated with the treatment of cardiovascular disease: III. Artificial pacemakers
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Article
Continuousin-vivo monitoring of arterial oxygen tension in a patient treated with bleomycin
Patients receiving bleomycin therapy may develop pulmonary fibrosis. The risk offibrosis is increased by the administration of general anaesthesia and fatal cases with pulmonary lesions resembling those of “ox...
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Article
Cardiac arrest following protamine administration
A case report of fatal cardiac arrest following protamine reversal of systemic heparinization during vascular surgery is presented. Patients who have received protamine zinc insulin, NPH insulin, and those wit...