139 Result(s)
-
Article
Open AccessMAP4K4 exacerbates cardiac microvascular injury in diabetes by facilitating S-nitrosylation modification of Drp1
Dynamin-related protein 1 (Drp1) is a crucial regulator of mitochondrial dynamics, the overactivation of which can
-
Article
Effect of Heat Treatment on Microstructure and Wear Behavior of Laser Clad FeCoCrMoNi High-Entropy Alloy Coatings
The microstructure and wear behavior of laser cladding FeCoCrMoNi high-entropy alloy (HEA) coating on Q235 steel substrate were studied. The coatings consisted of an FCC matrix, σ precipitates, and μ precipita...
-
Article
Measuring the synergy of air pollution and CO2 emission in Chinese urban agglomerations: an evaluation from the aggregate impact and correlation perspectives
Synergizing air pollution control and carbon emission reduction has been widely proposed and highlighted. Evaluating the synergy of air pollution and carbon emissions has been the primary concern and essential...
-
Article
Open AccessMap** the landscape: a bibliometric analysis of resting-state fMRI research on schizophrenia over the past 25 years
Schizophrenia, a multifaceted mental disorder characterized by disturbances in thought, perception, and emotion, has been extensively investigated through resting-state fMRI, uncovering changes in spontaneous ...
-
Article
Open AccessTREM2 deficiency impairs the energy metabolism of Schwann cells and exacerbates peripheral neurological deficits
Triggering receptor expressed on myeloid cells-2 (TREM2) has been implicated in susceptibility to neurodegenerative disease. Schwann cells (SCs), the predominant glial cell type in the peripheral nervous syste...
-
Article
Open AccessGenetic overlap between schizophrenia and cognitive performance
Schizophrenia (SCZ), a highly heritable mental disorder, is characterized by cognitive impairment, yet the extent of the shared genetic basis between schizophrenia and cognitive performance (CP) remains poorly...
-
Article
EGLN3 attenuates gastric cancer cell malignant characteristics by inhibiting JMJD8/NF-κB signalling activation independent of hydroxylase activity
The expression of Egl-9 family hypoxia-inducible factor 3 (EGLN3) is notably decreased in various malignancies, including gastric cancer (GC). While the predominant focus has been on the hydroxylase activity o...
-
Article
Open AccessUSP14 exhibits high expression levels in hepatocellular carcinoma and plays a crucial role in promoting the growth of liver cancer cells through the HK2/AKT/P62 axis
Hepatocellular carcinoma (HCC) is a common malignant tumor with strong invasiveness and poor prognosis. Previous studies have demonstrated the significant role of USP14 in various solid tumors. However, the ro...
-
Article
Open AccessCT-Guided Radiofrequency Ablation Targeting the Herniation Edge of the Cervical Disc for the Treatment of Neck Pain: A Retrospective Study
Sinuvertebral nerve overactivation is one of the mechanisms of neck pain caused by cervical disc herniation. Radiofrequency ablation (RFA) of sinuvertebral nerves has shown efficacy for the treatment of discog...
-
Article
Open AccessMechanosensitive channel of large conductance enhances the mechanical stretching-induced upregulation of glycolysis and oxidative metabolism in Schwann cells
Physical exercise directly stretching the peripheral nerve promotes nerve regeneration; however, its action mechanism remains elusive. Our present study aimed to investigate the effects of mechanosensitive cha...
-
Article
Open AccessCorrosion behavior of AlCrVTi light-weight high-entropy alloy coating in different corrosion environments
The excellent corrosion resistance of high-entropy alloys (HEAs) has attracted widespread attention in recent years. The focus of research is gradually shifting from the performance characterization to the com...
-
Article
Exponential Synchronization for Discrete-Time Delayed Neural Networks via Memory-Based Saturated Controller
This paper investigates the local exponential synchronization for discrete-time neural networks containing the time-varying delay via the memory-based saturated controller. Using the modified sector condition,...
-
Article
Open AccessThe impact of the new acute respiratory distress syndrome (ARDS) criteria on Berlin criteria ARDS patients: a multicenter cohort study
The European Society of Intensive Care Medicine (ESICM) recently recommended changes to the criteria of acute respiratory distress syndrome (ARDS), patients with high-flow oxygen were included, however, the ef...
-
Article
Comparative mitochondrial genome analysis of Cynoglossidae (Teleost: Pleuronectiformes) and phylogenetic implications
Generally, a teleostean group (e.g., family or genus) owns one type or a set of similar mitochondrial gene arrangement. It is interesting, however, that four different types of gene arrangement have been found...
-
Article
Open AccessA novel laboratory-based nomogram for assessing infection presence risk in acute-on-chronic liver failure patients
Accurate assessment of infection presence risk level, timely diagnosis, and effective control are critical for decreasing mortality of Acute‑on‑chronic liver failure (ACLF). We aimed to develop and validate a ...
-
Article
Open AccessA single-cell atlas of West African lungfish respiratory system reveals evolutionary adaptations to terrestrialization
The six species of lungfish possess both lungs and gills and are the closest extant relatives of tetrapods. Here, we report a single-cell transcriptome atlas of the West African lungfish (Protopterus annectens). ...
-
Article
Open AccessA nanoscale MOF-based heterogeneous catalytic system for the polymerization of N-carboxyanhydrides enables direct routes toward both polypeptides and related hybrid materials
Synthetic polypeptides have emerged as versatile tools in both materials science and biomedical engineering due to their tunable properties and biodegradability. While the advancements of N-carboxyanhydride (NCA)...
-
Article
Open AccessAnalysis of severe fever with thrombocytopenia syndrome cluster in east China
Severe fever with thrombocytopenia syndrome (SFTS) is a common tick-borne, natural focal disease. SFTS virus (SFTSV) transmission can occur between family members through close contact with an infected patient...
-
Article
Bearing Fault Diagnosis of Single-Channel Data by a 3D DCN with Bilinear LBP and Modified KPCA
The vibration signal has the characteristics of nonlinear and non-stationary, and the distribution of fault feature information contained in it is not concentrated. In addition, the nonlinear coupling of fault...
-
Article
Study on In Situ Formation of Intermetallic Compounds and Oxygen Adsorption of Ni/Al Coating
In order to predict the formation order of nickel-aluminum compounds. The first-principles calculation method is used to calculate the intermetallic compound formation mode of Ni/Al coating using the thermodyn...
