680 Result(s)
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Article
Dexmedetomidine alleviates Hypoxia/reoxygenation-induced mitochondrial dysfunction in cardiomyocytes via activation of Sirt3/Prdx3 pathway
Myocardial ischemia/reperfusion injury (MIRI) seriously threatens the health of people. The mitochondrial dysfunction in cardiomyocytes can promote the progression of MIRI. Dexmedetomidine (Dex) could alleviat...
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Water dissociation on graphene/Ir(111) studied by temperature-dependent X-ray photoelectron spectroscopy
Water dissociation induced by graphene has been investigated by using temperature-dependent X-ray photoelectron spectroscopy (XPS) from 120 K to room temperature. Comparative studies on the interaction of wate...
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Open AccessMXene-based flexible electronic materials for wound infection detection and treatment
Wound infection is a worldwide health issue that not only brings large detrimental effects to people’s physical and mental health, but also causes substantial economic burdens to society. By using traditional ...
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Superhydrophilic and Oil-Resistant SiO2/PU Fiber Membrane for Oil-In-Water Emulsion Separation under Gravity
A polyurethane membrane with interlayer channels was developed through electrospinning to separate oily sewage. To enhance its hydrophilicity, hydrophilic silica particles were grafted onto the fiber surface, ...
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Open AccessGenome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits
Hypertension affects more than one billion people worldwide. Here we identify 113 novel loci, reporting a total of 2,103 independent genetic signals (P < 5 × 10−8) from the largest single-stage blood pressure (BP...
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Scientific Advances and Weather Services of the China Meteorological Administration’s National Forecasting Systems during the Bei**g 2022 Winter Olympics
Since the Bei**g 2022 Winter Olympics was the first Winter Olympics in history held in continental winter monsoon climate conditions across complex terrain areas, there is a deficiency of relevant research, o...
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Efficient recovery of tungsten from scheelite concentrates using a sulfur-phosphorus mixed acid leaching system
In recent years, a new process for leaching scheelite concentrates with sulfur-phosphorus mixed acid has been successfully industrialized. This process suffers from the elimination of the retarding effect of c...
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Cpd-A1 alleviates acute kidney injury by inhibiting ferroptosis
Acute kidney injury (AKI) is defined as sudden loss of renal function characterized by increased serum creatinine levels and reduced urinary output with a duration of 7 days. Ferroptosis, an iron-dependent reg...
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Open AccessExpert consensus on pediatric orthodontic therapies of malocclusions in children
Malocclusion, identified by the World Health Organization (WHO) as one of three major oral diseases, profoundly impacts the dental-maxillofacial functions, facial esthetics, and long-term development of ~260 m...
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Open AccessEfficacy and safety of antibiotics for treatment of leptospirosis: a systematic review and network meta-analysis
Leptospirosis, an important zoonotic bacterial disease, commonly affects resource-poor populations and results in significant morbidity and mortality worldwide. The value of antibiotics in leptospirosis remain...
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Numerical simulation investigation on the seismic performance of high-strength concrete columns reinforced with PVA fibers and HTRB630 steel bars
In this article, the seismic performance of PVA fibers and HTRB630 steel bars reinforced with high-strength concrete column specimens (FTRHCs) are investigated numerically. Based on the available experimental ...
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Correction to: Protective Effect of GM1 Attenuates Hippocampus and Cortex Apoptosis After Ketamine Exposure in Neonatal Rat via PI3K/AKT/GSK3β Pathway
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Open AccessOptimized BEAC conditioning regimen improves clinical outcomes of autologous hematopoietic stem cell transplantation in non-Hodgkin lymphomas
The conditioning regimen is an important part of autologous hematopoietic stem cell transplantation (ASCT). We explored the efficacy and safety of an optimized BEAC (adjusted-dose, intermediate-dose cytarabine...
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Prognostic Model Construction of Disulfidptosis-Related Genes and Targeted Anticancer Drug Research in Pancreatic Cancer
Pancreatic cancer stands as one of the most lethal malignancies, characterized by delayed diagnosis, high mortality rates, limited treatment efficacy, and poor prognosis. Disulfidptosis, a recently unveiled mo...
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Empirical research on technical efficiency of wind power industry in China based on SFA method
In recent years, the vigorous development of the wind power industry has become an important measure in the transformation of energy structure in China. However, the overall low technical efficiency of wind fa...
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Open AccessGenome-wide characterization of circulating metabolic biomarkers
Genome-wide association analyses using high-throughput metabolomics platforms have led to novel insights into the biology of human metabolism1–7. This detailed knowledge of the genetic determinants of systemic me...
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Research on the effects of machining paths and variable parameters of different passes on defects in multi-pass single-point incremental forming
Multi-pass single-point incremental forming achieves large-angle part processing through multiple forming, and as the number of forming times increases, the number of forming defects on the workpiece also incr...
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Open AccessInsomnia and anxiety among COVID-19 patients in China: the chain mediating effect of psychological capital and self-esteem
The outbreak of Corona Virus Disease (COVID-19) in 2019 has continued until now, posing a huge threat to the public’s physical and mental health, resulting in different degrees of mental health problems. As a ...
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Investigation of the mutual crosstalk between ER stress and PI3K/AKT/mTOR signaling pathway in iron overload-induced liver injury in chicks
Iron is an essential element for the normal functioning of living organisms, but excessive iron deposition can lead to organ damage. This study aims to investigate the interaction between the endoplasmic retic...
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Open AccessEnantioselective functionalization of unactivated C(sp3)–H bonds through copper-catalyzed diyne cyclization by kinetic resolution
Site- and stereoselective C–H functionalization is highly challenging in the synthetic chemistry community. Although the chemistry of vinyl cations has been vigorously studied in C(sp3)–H functionalization reacti...
