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Article
Open AccessHigh-level production of nervonic acid in the oleaginous yeast Yarrowia lipolytica by systematic metabolic engineering
Nervonic acid benefits the treatment of neurological diseases and the health of brain. In this study, we employed the oleaginous yeast Yarrowia lipolytica to overproduce nervonic acid oil by systematic metabolic ...
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Article
Open AccessB7-H3 chimeric antigen receptor-modified T cell shows potential for targeted treatment of acute myeloid leukaemia
Chimeric antigen receptor (CAR)-T cell therapy is a novel type of immunotherapy. However, the use of CAR-T cells to treat acute myeloid leukaemia (AML) has limitations. B7-H3 is expressed in several malignanci...
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Article
Open AccessCD7-directed CAR T-cell therapy: a potential immunotherapy strategy for relapsed/refractory acute myeloid leukemia
Relapsed/refractory acute myeloid leukemia (AML) patients generally have a dismal prognosis and the treatment remains challenging. Due to the expression of CD7 on 30% AML and not on normal myeloid and erythroi...
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Article
Open AccessZkscan3 affects erythroblast development by regulating the transcriptional activity of GATA1 and KLF1 in mice
ZKSCAN3 encodes a zinc-finger transcription factor that regulates the expression of important genes and plays a significant role in tumor development, pathogenesis, and metastasis. However, its biological functio...
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Article
Open AccessRemarkably enhanced piezo-photocatalytic performance in BaTiO3/CuO heterostructures for organic pollutant degradation
Introducing polarization field of piezoelectric materials is an effective strategy to improve photocatalytic performance. In this study, a new type of BaTiO3/CuO heterostructure catalyst was designed and synthesi...
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Chapter and Conference Paper
Memory Confidentiality and Integrity Protection Technology
In most existing computer systems, data transmission and preservation in the form of plaintext are vulnerable to various attacks. In this paper, we use Parralelized memory Confidentiality and Integrity Protect...
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Article
Energy-saving synthesis of electrolytic manganese dioxide using oxygen cathode with Pt/TiO2-CNx nanocatalysts
The awareness of energy, environment, and economy for electrolysis has required the development of new methods to prevent environmental pollution, such as the emission of acid fog, CO2, and SO2. Hence, the use of...
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Article
Open AccessResearch trends in electrochemical technology for water and wastewater treatment
It is difficult to completely degrade wastewater containing refractory pollutants without secondary pollution by biological treatment, as well as physical–chemical process. Therefore, electrochemical technolog...
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Article
Open AccessPhase 1 clinical trial demonstrated that MUC1 positive metastatic seminal vesicle cancer can be effectively eradicated by modified Anti-MUC1 chimeric antigen receptor transduced T cells
Recent progress in chimeric antigen receptor-modified T-cell (CAR-T cell) technology in cancer therapy is extremely promising, especially in the treatment of patients with B-cell acute lymphoblastic leukemia. ...
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Article
Molecular cloning of a novel subtilisin-like protease (Pr1A) gene from the biocontrol fungus Isaria farinosa
Fungal proteases, such as subtilisin-like serine protease (Pr1) and trypsin-like serine protease (Pr2), play an important role in penetration through the host cuticle in entomopathogenic fungi, including Isaria f...
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Article
Effect of heat treatment of titanium substrates on the properties of IrO2-Ta2O5 coated anodes
The Ti substrates of IrO2-Ta2O5 coated anodes were treated by solid-solution and aging, stress relieving annealing, and recrystallization annealing, and the coatings were prepared by thermal decomposition of a mi...
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Article
Surface hardening of Fe-based alloy powders by Nd:YAG laser cladding followed by electrospark deposition with WC-Co cemented carbide
This paper presents the results of a study concerned with the surface hardening of Fe-based alloys and WC-8Co cemented carbide by integrating laser cladding and the electrospark deposition processes. Specimens...
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Article
Wear characteristics of spheroidal graphite roll WC-8Co coating produced by electro-spark deposition
Electro-spark deposition (ESD) was adopted for preparing high property coatings by depositing WC-8Co cemented carbide on an spheroidal graphite roll substrate. The microstructure and properties of the coating ...
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Chapter and Conference Paper
Optimization of the Switches in Storage Networks
In the Storage Area Network (SAN), the mature network technology is used to substitute for the IO bus. Usually, the common switch is used in the storage network especially in the iSCSI storage system. Because ...
