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Fatal Hemorrhage Complicating Intracranial Stenting After Failed Thrombectomy for Intracranial Atherosclerotic Stenosis in a Patient with Moderate Stroke: Risk Factors for Hemorrhagic Transformation, Red Flags, and Lessons Learned
Most large vessel occlusions (LVOs) are secondary to emboli of cardiac or cervical artery origin. Current stent retrieval and aspiration thrombectomy...
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Left Atrial Appendage Closure Periprocedural Imaging
Percutaneous left atrial appendage closure (LAAC) has become an important tool for stroke prevention in patients with nonvalvular atrial fibrillation...
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Obesity and Metabolic Syndrome in South Asians
Obesity and the metabolic syndromeObesityand metabolic syndromeMetabolic syndrome (MetS) are chronic conditions resulting from biological,...
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Tandem Extra- and Intracranial ICA “T” Occlusions Treated by Means of Double Stentriever (T Stent Array) Thrombectomy, and Cervical Stent-Assisted Balloon Angioplasty
The double stentriever technique, which employs two stentrievers simultaneously at the occlusion site, can be beneficial for sizeable neurovascular...
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Inferior Vena Cava Filter Retrieval
Most patients with venous thromboembolic conditions are managed with anticoagulation therapy; however, implantation of inferior vena cava (IVC)...
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Sudden Arrhythmic Death Syndrome and Ventricular Tachycardia in Children
Sudden arrhythmogenic death in apparently healthy children is an unexpected event. Usually characterized by ventricular tachycardia devolving into...
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Temporary and Permanent Pacemakers and Automated Internal Defibrillators
While many of the principles of device-based arrhythmia management are universal, there are important differences between typical adult management...
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Rescue Stenting After Failed Thrombectomy of a Large Vessel Occlusion Related to Calcified Cerebral Embolus
Reperfusion of large vessel occlusion caused by calcified cerebral embolism remains a challenge, and failure to achieve reperfusion results in poor...
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Recurrent Large Vessel Occlusion Requiring Repeat Mechanical Thrombectomy Within 24 Hours with Good Clinical Evolution: Atrial Fibrillation Meets Malignancy and Immunotherapy – 1st Procedure, Stent Retriever; 2nd Procedure, Aspiration
Mechanical thrombectomy (MT) in the first 24 h after system onset has become the standard of care for the treatment of acute ischemic stroke due to...
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Mechanical Thrombectomy in Difficult Access, Tortuous ICA Anatomy: When an Intermediate Catheter Replaces the Balloon-Guiding Catheter
Thrombectomy has become established as a successful treatment strategy for ischemic stroke, and an increasing number of patients are undergoing this...
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Decellularized Extracellular Matrix for Modeling Cardiac Extracellular Microenvironment
The extracellular matrix (ECM) forms most of the tissue microenvironment and is in a constant and dynamic equilibrium with cells. The...
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Generation of 3D-Multicellular Human iPSC-Heart Organoids for the Noninvasive Assessment of Cardiac Fibrosis
The lack of a precise noninvasive, clinical evaluation method for cardiac fibrosis hinders the development of successful treatments that can...
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Rat Model of Isoproterenol-Induced Myocardial Injury
Isoproterenol (ISO) administration produces significant biochemical and histological changes including oxidative stress, reactive oxygen species...
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Porcine Model of Hypertrophy-Independent Left Ventricular Stiffening via Repetitive Pressure Overload
Diastolic dysfunction arising from alterations in myocardial structure and/or function is a central component of several cardiovascular disorders,...
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Culturing Cardiac Tissue Slices Under Continuous Physiological Mechanical Stretches
Testing drugs in vivo and in vitro have been essential elements for the discovery of new therapeutics. Due to the recent advances in in vitro cell...
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In Vitro Experimental Approach for Studying Human Pulmonary Artery Smooth Muscle Cells and Endothelial Cells Proliferation and Migration
Pulmonary arterial hypertension (PAH) is a severe vascular disease characterized by persistent precapillary pulmonary hypertension, leading to right...
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Imaging and Analysis of the Dynamics of Filamentous Actin Structures in Live Endothelial Cells
The ability to view and record the movements of subcellular structures is a powerful tool that has accelerated the discovery and understanding of...
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Isolation and Culture of Human Umbilical Vein Endothelial Cells (HUVECs)
This protocol describes a simple and an economical method for isolation of endothelial cells from human umbilical vein. Umbilical cord is easily...
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Assessment of Endothelial Barrier Functions in Extra Embryonic Vasculature of Chick Embryo as an Alternative Model
Vascular permeability, a tightly regulated process, is a direct measure of angiogenic and immune responses in the endothelium altered in several...
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Determination of Tight Junction Integrity in Brain Endothelial Cells Based on Tight Junction Protein Expression
Blood-brain barrier (BBB) dysfunction and hyperpermeability that occurs following traumatic and ischemic insults lead to various downstream ill...