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Driving Without a License: Career Advice from a Non-PhD Scientist
Jason Williams, Assistant Director, Diversity and Research Readiness at the Cold Spring Harbor Laboratory DNA Learning Center gives career and advice...
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How to Transition from Academia to Biotech (a Personal Perspective)
In this chapter a set of basic steps for academics to go about applying for their first industry job are outlined and explained. The steps are based...
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A Biologist’s Path to a Career in Finance
I work at the interface of science, biotechnology, and finance. I am the director of research at LifeSci Capital, an investment bank that focuses...
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A Long and Winding Road: Reflections on a Career in Science Policy
Science policy is an exciting and fulfilling career path for those trained as scientists, but the road from Ph.D. to science policy professional can...
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The Unplanned Journey: From the Bench to University Leadership to Biotech Company CEO
My journey as a scientist started as most do. Beginning in graduate school followed by a postdoctoral position and then my first tenure-track...
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In Vitro and In Silico ADME Prediction
Pharmacokinetic issues have been identified as a major cause for the attrition of new chemical entities in drug discovery. High development costs and...
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Advanced Techniques for Quality Assessment of Nanocarriers
Nanoparticle characterization is crucial for develo** and optimizing nanocarriers, as it is necessary to have a comprehensive understanding of...
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Introduction: Biopharmaceutics and Pharmacokinetics
Biopharmaceutics and Pharmacokinetics are pharmaceutical disciplines that are useful for improving the outcome of drug therapies, assisting drug...
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Blood Flow Distribution and Membrane Transporters as Determinant Factors of Tissue Drug Concentration
The free drug hypothesis states that the non-ionized free drug concentrations will have the same value in all the aqueous spaces of the body, once...
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Drug-Drug and Food-Drug Interactions of Pharmacokinetic Nature
The most relevant pharmacokinetic mechanisms of drug-drug (DD) and food-drug (FD) interactions are summarized from a perspective that will allow the...
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Regulatory Requirements and Applications of Physiologically Based Pharmacokinetic Models
Physiologically based pharmacokinetic (PBPK) models have become a key tool to reduce the uncertainty and assure the best benefit-risk decisions in a...
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The Submission Process
There are many criteria for selecting a suitable journal to submit a manuscript to. Journals can be open access, free for all to read and paid by the...
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Optimal Use of the English Language
Scientific English is highly codified. Certain words and phrases often return in many articles. This serves to provide optimal clarity. The best way...
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Other Scientific Texts
In addition to research papers, young scientists may have to write research proposals, review articles or internship reports. Reviews discuss the...
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What Is Science?
Science is an intricate system that uses observations, research, and investigations to achieve insight in nature and describe it truthfully. What do...
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Presenting the Data
Figures and tables are essential tools to summarize data and present them to the reader. There is a large variety of figures, plots, tables, and...
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Hemodynamics During Development and Postnatal Life
A well-developed heart is essential for embryonic survival. There are constant interactions between cardiac tissue motion and blood flow, which...
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Epigenetics
Epigenetics is the study of heritable changes to the genome and gene expression patterns that are not caused by direct changes to the DNA sequence....
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Molecular Pathways and Animal Models of Atrioventricular Septal Defect
The development of a fully functional four-chambered heart is critically dependent on the correct formation of the structures that separate the...
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Posttranscriptional Regulation by Proteins and Noncoding RNAs
Posttranscriptional regulation comprises those mechanisms occurring after the initial copy of the DNA sequence is transcribed into an intermediate...