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Impact of medicine shortages on hospital practice: role of a multidisciplinary medicine shortages team
Medicine shortages are an increasing issue, with broad public health implications for patients, health professionals and institutions. Despite...
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Predicting pharmaceutical prices. Advances based on purchase-level data and machine learning
BackgroundIncreased costs in the health sector have put considerable strain on the public budgets allocated to pharmaceutical purchases. Faced with...
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Feeding Assistance Skill Score: development and verification of reliability and validity
PurposeFeeding assistance should be safe and improve the assisted individual’s ability to feed, yet objective tools for evaluating these skills are...
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Therapeutic Effect of Melatonin on CCl4-Induced Fibrotic Liver Model by Modulating Oxidative Stress, Inflammation, and TGF-β1 Signaling Pathway in Pinealectomized Rats
The study aimed to determine the CCl 4 -induced liver fibrosis model in pinealectomized rats and biochemically, immunohistochemically, and...
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The strongest predictors of compliance with health protocols among marketers and guilds based on the transtheoretical model
BackgroundGlobal communication, an integral part of modern life, increases the risk of transmitting infectious diseases to individuals. Based on the...
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Estimated Incidence of Hospitalizations Attributable to RSV Infection Among Adults in Ontario, Canada, Between 2013 and 2019
IntroductionAdult respiratory syncytial virus (RSV) burden is underestimated due to non-specific symptoms, limited standard-of-care and delayed...
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Sex ratio at birth across 100 years in Sweden and risk of cardiovascular disease and all-cause mortality – a national register study
The human sex ratio at birth (SRB) undergoes temporary changes around a mean proportion of 0.51 male births. SRB has been well studied for...
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Association of ambient temperature on acute ischemic stroke in Yancheng, China
BackgroundAcute ischemic stroke (AIS) is a major global public health issue. There is limited research on the relationship between ambient...
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Anti-C5 monoclonal antibody treatment showing pathological resolution of complement-mediated atypical hemolytic uremic syndrome: a case report
BackgroundNo reports have shown histological changes before and after anti-C5 monoclonal antibody treatment in patients with atypical hemolytic...
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Time to recovery and predictors among admitted preterm neonates in the neonatal intensive care units of public hospitals of Addis Ababa, Ethiopia, 2021
IntroductionEthiopia implemented measures to reduce preterm mortality, and much is currently being done to avoid preterm death, yet preterm death...
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Isotoosendanin inhibits triple-negative breast cancer metastasis by reducing mitochondrial fission and lamellipodia formation regulated by the Smad2/3-GOT2-MYH9 signaling axis
Triple-negative breast cancer (TNBC) is incurable and prone to widespread metastasis. Therefore, identification of key targets for TNBC progression...
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Evaluation of the effect of trendelenburg position duration on intracranial pressure in laparoscopic hysterectomies using ultrasonographic optic nerve sheath diameter measurements
BackgroundDuring laparoscopic surgery, pneumoperitoneum and Trendelenburg positioning applied to provide better surgical vision can cause many...
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From traditional to transactional: exploration of khat use in Ethiopia through an interpretative phenomenological analysis
Khat, a naturally growing stimulant, has seen a significant increase in both consumption and cultivation in eastern Ethiopia. This reliance on khat...
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ISIS 449884 Injection Add-On to Metformin in Patients with Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Phase II Clinical Study
IntroductionISIS 449884, a 2′- O -methoxyethyl antisense oligonucleotide that targets the glucagon receptor (GCGR), has demonstrated an ability to...
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Kalanchoe pinnata (Lam.) Pers. Leaf ethanolic extract exerts selective anticancer activity through ROS-induced apoptotic cell death in human cancer cell lines
BackgroundThe leaves of Kalanchoe pinnata (Lam.) Pers. ( K. pinnata ), a succulent plant native to tropical regions, are used as a medicinal...
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A comparison of brown fat tissue related hormone levels in metabolically healthy and unhealthy individuals with obesity
PurposeOne of the key functions of brown adipose tissue is its positive impact on metabolism. This study aimed to examine the potential involvement...
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Treatment strategy for compartment syndrome at multiple regions due to injuries caused by a tree fall: a case report
BackgroundCompartment syndrome commonly occurs in patients with forearm and lower leg fractures. Compartment syndromes of the gluteal and thigh...
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Initiation of Alcohol Consumption Among the Tribal Male Adolescents in Dooars Region of West Bengal: A Failure Event Analysis Approach
BackgroundAlcohol consumption is a significant social and health problem among tribal male adolescents. The Dooars region of West Bengal has the...
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Investigation into the role of H2-Ab1 in vascular remodeling in pulmonary arterial hypertension via Bioinformatics
BackgroundPulmonary arterial hypertension (PAH) is a progressive disease of vascular remodeling characterized by persistent pulmonary arterial...
