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Patterns and trends in melanoma mortality in the United States, 1999–2020
IntroductionMelanoma, a deadly form of skin cancer, has witnessed a notable increase in incidence over the past decades. Despite advancements in...
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The molecular mechanisms of Abyssinone-I protect against Alzheimer’s disease: an in-silico study
There is limited available information regarding the biological activity of Abyssinone-I, apart from its recognized antioxidant and cytotoxic...
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Immune thrombocytopenia (ITP): historical perspectives, pathophysiology, and treatment advances
Immune thrombocytopenia (ITP) is a hematologic disorder characterized by a low platelet count, leading to an increased risk of bleeding. This review...
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Manufacturing mesenchymal stromal cells in a microcarrier-microbioreactor platform can enhance cell yield and quality attributes: case study for acute respiratory distress syndrome
Mesenchymal stem and stromal cells (MSCs) hold potential to treat a broad range of clinical indications, but clinical translation has been limited to...
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Rapid identification of early infections in febrile patients after CD19 target CAR-T cell therapy for B-cell malignancies
BackgroundCD19-targeted chimeric antigen receptor T (CAR-T) cell therapy stands out as a revolutionary intervention, exhibiting remarkable remission...
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Hypermethylated TAGMe as a universal-cancer-only methylation marker and its application in diagnosis and recurrence monitoring of urothelial carcinoma
BackgroundUrothelial carcinoma (UC) is the second most common urological malignancy. Despite numerous molecular markers have been evaluated during...
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Peer2Me – evaluation of a peer supported program for adolescent and young adult (AYA) cancer patients: study protocol of a randomised trial using a comprehensive cohort design
BackgroundDevelo** cancer in young adulthood is a non-normative life event and associated with adverse physical, social and psychological...
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Estimating regional and national cancer incidence in Uganda: a retrospective population-based study, 2013–2017
BackgroundCancer is becoming a major health problem in Uganda. Cancer control requires accurate estimates of the cancer burden for planning and...
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Cognitive reappraisal and affective response to physical activity: associations with physical activity behavior
ObjectiveCognitive reappraisal (CR), as an adaptive emotion regulation strategy, may play a role in transforming affect in a positive direction...
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Examining the performance of responding to the Khoy earthquake 2022, challenges, strengths, and lessons learned: thematic analysis
ObjectiveDisasters in develo** countries result in higher human and financial losses compared to global standards, with the death rate being 12...
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Serum miRNA-1 may serve as a promising noninvasive biomarker for predicting treatment response in breast cancer patients receiving neoadjuvant chemotherapy
BackgroundMicroRNA-1 (miR-1) is a tumour suppressor that can inhibit cell proliferation and invasion in several cancer types. In addition, miR-1 was...
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Leveraging a neutrophil-derived PCD signature to predict and stratify patients with acute myocardial infarction: from AI prediction to biological interpretation
BackgroundProgrammed cell death (PCD) has recently been implicated in modulating the removal of neutrophils recruited in acute myocardial infarction...
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Rapid detection of lung cancer based on serum Raman spectroscopy and a support vector machine: a case-control study
BackgroundEarly screening and detection of lung cancer is essential for the diagnosis and prognosis of the disease. In this paper, we investigated...
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Pulmonary functions test in asymptomatic rheumatoid lung disease patients: a hospital-based study
BackgroundAs a common extra-articular symptom of rheumatoid arthritis (RA), pulmonary involvement affects 20–67% of patients and accounts for 10–20%...
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An expedited screening platform for the discovery of anti-ageing compounds in vitro and in vivo
BackgroundRestraining or slowing ageing hallmarks at the cellular level have been proposed as a route to increased organismal lifespan and...
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Using clotted, pelleted blood samples for direct molecular detection of Bartonella spp. in small mammal wildlife surveillance studies
ObjectiveBartonella are emerging bacterial zoonotic pathogens. Utilization of clotted blood samples for surveillance of these bacteria in wildlife...
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Radiology of fibrosis. Part I: Thoracic organs
Sustained injury from factors such as hypoxia, infection, or physical damage may provoke improper tissue repair and the anomalous deposition of...
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Reliability and validity study of the Chinese version of the Cerebellar Cognitive Affective Syndrome Scale in patients with cerebellar injury
PurposeTo preliminarily investigate the reliability and validity of the Chinese version of the Cerebellar Cognitive Affective Syndrome Scale (CCAS...
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Comprehensive investigation of malignant epithelial cell-related genes in clear cell renal cell carcinoma: development of a prognostic signature and exploration of tumor microenvironment interactions
Clear cell renal cell carcinoma (ccRCC) is a prevalent malignancy with complex heterogeneity within epithelial cells, which plays a crucial role in...
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An overview of early-onset cerebellar ataxia: a practical guideline
Early onset ataxias (EOAs) are a heterogeneous group of rare neurological disorders that not only involve the central and peripheral nervous system...
