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201 Result(s)
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Article
Open AccessMutation analysis for newly suggested 30 Y-STR loci with high mutation rates in Chinese father-son pairs
Rapidly mutating Y-STRs (RM Y-STRs) harbor great potential to distinguish male relatives and achieve male identification. However, forensic applications were greatly limited by the small number of the initiall...
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Open AccessUltra-flat and long-lived plasmons in a strongly correlated oxide
Plasmons in strongly correlated systems are attracting considerable attention due to their unconventional behavior caused by electronic correlation effects. Recently, flat plasmons with nearly dispersionless f...
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Open AccessComparing two different automatic methods to measure femoral neck-shaft angle based on PointNet++ network
Accurate measurement of the femoral neck-shaft angle (NSA) is of great significance for diagnosing hip joint diseases and preoperative planning of total hip arthroplasty. However, the repeatability of manual m...
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Open AccessAuthor Correction: Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice
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Open AccessThe role of iconic practice in Bruno’s gnoseology
The iconic praxis plays a vital role in Giordano Bruno’s gnoseological process. Bruno considers the image to be both sensitive and intelligible according to its faculty of Phantasia, which traditionally is condem...
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Open AccessChromosome-level and haplotype-resolved genome provides insight into the tetraploid hybrid origin of patchouli
Patchouli (Pogostemon cablin (Blanco) Benth.), a member of the Lamiaceae family, is an important aromatic plant that has been widely used in medicine and perfumery. Here, we report a 1.94 Gb chromosome-scale asse...
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Open AccessCirculating miR-141 as a potential biomarker for diagnosis, prognosis and therapeutic targets in gallbladder cancer
MicroRNA-141(miR-141) has been reported to play vital roles in the regulation of carcinogenesis and cancer progression. However, the biological function of miR-141 in GBC has received less attention. The aim o...
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Open AccessNecrolytic migratory erythema is an important visual cutaneous clue of glucagonoma
Glucagonoma is an extremely rare neuroendocrine tumor that arises from pancreatic islet alpha cells. Although glucagonoma is usually accompanied by a variety of characteristic clinical symptoms, early diagnosi...
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Open AccessA Maluku Sea intermediate western boundary current connecting Pacific Ocean circulation to the Indonesian Throughflow
The Indonesian Throughflow plays an important role in the global ocean circulation and climate. Existing studies of the Indonesian Throughflow have focused on the Makassar Strait and the exit straits, where th...
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Open AccessConstruction of emissive ruthenium(II) metallacycle over 1000 nm wavelength for in vivo biomedical applications
Although Ru(II)-based agents are expected to be promising candidates for substituting Pt-drug, their in vivo biomedical applications are still limited by the short excitation/emission wavelengths and unsatisfa...
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Open AccessA polygenic risk score for nasopharyngeal carcinoma shows potential for risk stratification and personalized screening
Polygenic risk scores (PRS) have the potential to identify individuals at risk of diseases, optimizing treatment, and predicting survival outcomes. Here, we construct and validate a genome-wide association stu...
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Open AccessAntiferroelectric negative capacitance from a structural phase transition in zirconia
Crystalline materials with broken inversion symmetry can exhibit a spontaneous electric polarization, which originates from a microscopic electric dipole moment. Long-range polar or anti-polar order of such pe...
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Open AccessLymphocyte infiltration and thyrocyte destruction are driven by stromal and immune cell components in Hashimoto’s thyroiditis
Hashimoto’s thyroiditis (HT) is the most common autoimmune disease characterized by lymphocytic infiltration and thyrocyte destruction. Dissection of the interaction between the thyroidal stromal microenvironm...
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Open AccessDevelopment and validation of a machine learning method to predict intraoperative red blood cell transfusions in cardiothoracic surgery
Accurately predicting red blood cell (RBC) transfusion requirements in cardiothoracic (CT) surgery could improve blood inventory management and be used as a surrogate marker for assessing hemorrhage risk preop...
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Open AccessINTS8 is a therapeutic target for intrahepatic cholangiocarcinoma via the integration of bioinformatics analysis and experimental validation
Intrahepatic cholangiocarcinoma (CHOL) remains a rare malignancy, ranking as the leading lethal primary liver cancer worldwide. However, the biological functions of integrator complex subunit 8 (INTS8) in CHOL...
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Open AccessThree chromosome-level duck genome assemblies provide insights into genomic variation during domestication
Domestic ducks are raised for meat, eggs and feather down, and almost all varieties are descended from the Mallard (Anas platyrhynchos). Here, we report chromosome-level high-quality genome assemblies for meat...
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Open AccessCD177 modulates the function and homeostasis of tumor-infiltrating regulatory T cells
Regulatory T (Treg) cells are one of the major immunosuppressive cell types in cancer and a potential target for immunotherapy, but targeting tumor-infiltrating (TI) Treg cells has been challenging. Here, usin...
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Open AccessDirect access to spirocycles by Pd/WingPhos-catalyzed enantioselective cycloaddition of 1,3-enynes
Spirocycles play an important role in drug discovery and development. The direct, catalytic, and enantioselective synthesis of spirocycles from readily available starting materials and in an atom economic mann...
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Open AccessSingle-atom catalyst for high-performance methanol oxidation
Single-atom catalysts have been widely investigated for several electrocatalytic reactions except electrochemical alcohol oxidation. Herein, we synthesize atomically dispersed platinum on ruthenium oxide (Pt1/RuO
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Open AccessRobust and accurate prediction of protein–protein interactions by exploiting evolutionary information
Various biochemical functions of organisms are performed by protein–protein interactions (PPIs). Therefore, recognition of protein–protein interactions is very important for understanding most life activities,...