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  1. Article

    Open Access

    Spatiotemporal Co-existence of Female Thyroid and Breast Cancers in Hangzhou, China

    Thyroid and breast cancers (TC, BC) are common female malignant tumors worldwide. Studies suggest that TC patients have a higher BC risk, and vice versa. However, it has not been investigated quantitatively if...

    Xufeng Fei, George Christakos, Zhaohan Lou, Yanjun Ren, Qingmin Liu in Scientific Reports (2016)

  2. Article

    Open Access

    Interferon regulatory factor 3 is a key regulation factor for inducing the expression of SAMHD1 in antiviral innate immunity

    SAMHD1 is a type I interferon (IFN) inducible host innate immunity restriction factor that inhibits an early step of the viral life cycle. The underlying mechanisms of SAMHD1 transcriptional regulation remains...

    Shen Yang, Yuan Zhan, Yanjun Zhou, Yifeng Jiang, Xuchen Zheng in Scientific Reports (2016)

  3. Article

    Open Access

    Mitogenomic perspectives on the origin of Tibetan loaches and their adaptation to high altitude

    Tibetan loaches are the largest group of Tibetan fishes and are well adapted to the Tibetan Plateau. To investigate the origin of Tibetan loaches and their adaptations to the Tibetan Plateau, we determined 32 ...

    Ying Wang, Yanjun Shen, Chenguang Feng, Kai Zhao, Zhaobin Song in Scientific Reports (2016)

  4. Article

    Open Access

    Phytochrome B and REVEILLE1/2-mediated signalling controls seed dormancy and germination in Arabidopsis

    Seeds maintain a dormant state to withstand adverse conditions and germinate when conditions become favourable to give rise to a new generation of flowering plants. Seed dormancy and germination are tightly co...

    Zhimin Jiang, Gang Xu, Yanjun **g, Weijiang Tang, Rongcheng Lin in Nature Communications (2016)

  5. Article

    Open Access

    Thermal stress depletes energy reserves in Drosophila

    Understanding how environmental temperature affects metabolic and physiological functions is of crucial importance to assess the impacts of climate change on organisms. Here, we used different laboratory strai...

    Peter Klepsatel, Martina Gáliková, Yanjun Xu, Ronald P. Kühnlein in Scientific Reports (2016)

  6. Article

    Open Access

    Study on Synergistic Mechanism of Inhibitor Mixture Based on Electron Transfer Behavior

    Mixing is an important method to improve the performance of surfactants due to their synergistic effect. The changes in bonding interaction and adsorption structure of IM and OP molecules before and after co-a...

    Peng Han, Yang He, Changfeng Chen, Haobo Yu, Feng Liu, Hong Yang in Scientific Reports (2016)

  7. No Access

    Article

    Cobalt carbide nanoprisms for direct production of lower olefins from syngas

    Lower olefins are hydrocarbons that are widely used in the chemical industry, and can be generated from syngas by the ‘Fischer–Tropsch to olefins’ process; here, a new catalyst is described that can generate l...

    Liangshu Zhong, Fei Yu, Yunlei An, Yonghui Zhao, Yuhan Sun, Zhengjia Li in Nature (2016)

  8. Article

    Open Access

    In Situ Growth of Highly Adhesive Surface Layer on Titanium Foil as Durable Counter Electrodes for Efficient Dye-sensitized Solar Cells

    Counter electrodes (CEs) of dye-sensitized solar cells (DSCs) are usually fabricated by depositing catalytic materials on substrates. The poor adhesion of the catalytic material to the substrate often results ...

    Wantao Liu, Peng Xu, Yanjun Guo, Yuan Lin, **ong Yin, Guangshi Tang in Scientific Reports (2016)

  9. Article

    Open Access

    cAMP-PKA-CaMKII signaling pathway is involved in aggravated cardiotoxicity during Fuzi and Beimu Combination Treatment of Experimental Pulmonary Hypertension

    Aconiti Lateralis Radix Praeparata (Fuzi) and Fritillariae Thunbergii bulbus (Beimu) have been widely used clinically to treat cardiopulmonary related diseases in China. However, according to the classic rules of...

    Pengwei Zhuang, Yingying Huang, Zhiqiang Lu, Zhen Yang, Liman Xu in Scientific Reports (2016)

  10. Article

    Open Access

    Study on spin and optical polarization in a coupled InGaN/GaN quantum well and quantum dots structure

    The spin and optical polarization based on a coupled InGaN/GaN quantum well (QW) and quantum dots (QDs) structure is investigated. In this structure, spin-electrons can be temporarily stored in QW, and spin in...

    Jiadong Yu, Lai Wang, Di Yang, Jiyuan Zheng, Yuchen **ng, Zhibiao Hao in Scientific Reports (2016)

  11. Article

    Open Access

    Low-temperature-dependent property in an avalanche photodiode based on GaN/AlN periodically-stacked structure

    In ultra-high sensitive APDs, a vibrate of temperature might bring a fatal decline of the multiplication performance. Conventional method to realize a temperature-stable APD focuses on the optimization of devi...

    Jiyuan Zheng, Lai Wang, Di Yang, Jiadong Yu, **ao Meng, Zhibiao Hao in Scientific Reports (2016)

  12. Article

    Open Access

    Enterohemorrhagic Escherichia coli promotes the invasion and tissue damage of enterocytes infected with Candida albicans in vitro

    The principal aim of this study was to investigate the in vitro co-infection of Caco-2 cells with Candida albicans and enterohemorrhage Escherichia coli (EHEC). The ability of both species to colonize or invade t...

    Weiming Yang, Yanjun Zhou, Chunrong Wu, Jianguo Tang in Scientific Reports (2016)

  13. Article

    Open Access

    Associations of blood lead levels with reproductive hormone levels in men and postmenopausal women: Results from the SPECT-China Study

    We examined whether blood lead levels (BLLs) were associated with reproductive hormone levels in a cross-sectional study using data from the SPECT-China study. We selected 2286 men and 1571 postmenopausal wome...

    Chi Chen, Ningjian Wang, Hualing Zhai, **aomin Nie, Honglin Sun in Scientific Reports (2016)

  14. Article

    Open Access

    A high-throughput fluorimetric microarray with enhanced fluorescence and suppressed “coffee-ring” effects for the detection of calcium ions in blood

    A rapid, ultrasensitive, and high-throughput fluorimetric microarray method has been developed using hydrophobic pattern as the microarray substrate and 3-aminopropyltriethoxysilane-coupled carboxylic acid cal...

    Yanjun Ding, Jiang Ling, Yuchun Qiao, Zhengjian Li, Zongzhao Sun in Scientific Reports (2016)

  15. Article

    Open Access

    The Identification and Characterization of Two Novel Epitopes on the Nucleocapsid Protein of the Porcine Epidemic Diarrhea Virus

    Porcine epidemic diarrhea virus (PEDV) is a highly contagious coronavirus that causes severe diarrhea and death, particularly in neonatal piglets. The nucleocapsid protein (N protein) of PEDV presents strong immu...

    Kang Wang, Chun **e, Jianan Zhang, Wenchao Zhang, Deqiang Yang in Scientific Reports (2016)

  16. Article

    Open Access

    Improved cold tolerance in Elymus nutans by exogenous application of melatonin may involve ABA-dependent and ABA-independent pathways

    Melatonin is an important secondary messenger that plays a central role in plant growth, as well as abiotic and biotic stress tolerance. However, the underlying physiological and molecular mechanisms of melato...

    Juanjuan Fu, Ye Wu, Yanjun Miao, Yamei Xu, Enhua Zhao, ** Wang in Scientific Reports (2017)

  17. Article

    Open Access

    Association of regular physical activity with total and cause-specific mortality among middle-aged and older Chinese: a prospective cohort study

    Association between physical activity and mortality has rarely been investigated among the Chinese population. Furthermore, the most appropriate amount of physical activity for longevity benefits remains uncle...

    Yun Zhou, Runbo Zhang, Yuewei Liu, Yanjun Guo, Dongming Wang in Scientific Reports (2017)

  18. Article

    Open Access

    Dopamine-functionalized mesoporous onion-like silica as a new matrix for immobilization of lipase Candida sp. 99-125

    Dopmine functionalized mesoporous onion-like silica (DPMS) was synthesized via a biomimetic coating, and lipase Candida sp. 99-125 (LCS) was immobilized in DPMS (LCS@DPMS) by physical adsorption in this study. Th...

    Junkai Gao, Yanjun Jiang, **shu Lu, Zhi Han, Jiajia Deng, Yan Chen in Scientific Reports (2017)

  19. Article

    Open Access

    A de novo deletion mutation in SOX10 in a Chinese family with Waardenburg syndrome type 4

    Waardenburg syndrome type 4 (WS4) or Waardenburg-Shah syndrome is a rare genetic disorder with a prevalence of <1/1,000,000 and characterized by the association of congenital sensorineural hearing loss, pigmen...

    **ong Wang, Yaowu Zhu, Na Shen, **g Peng, Chunyu Wang, Haiyi Liu in Scientific Reports (2017)

  20. Article

    Open Access

    Quantification of re-absorption and re-emission processes to determine photon recycling efficiency in perovskite single crystals

    Photon recycling, that is, iterative self-absorption and re-emission by the photoactive layer itself, has been speculated to contribute to the high open-circuit voltage in several types of high efficiency sola...

    Yanjun Fang, Haotong Wei, Qingfeng Dong, **song Huang in Nature Communications (2017)

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