538 Result(s)

Article

Sex-dependent different clinicopathological characterization of Epstein–Barr virus-associated gastric carcinoma: a large-scale study

Epstein–Barr virus (EBV)-associated gastric cancer (EBVaGC) has been reported to account for approximately 5–16% of all GCs with good prognosis compared to EBV-negative GC. We evaluated the clinicopathological...

Ji-Hyun Kim, Nayoung Kim, Du Hyun Song, Yonghoon Choi, Eun-Bi Jeon… in Gastric Cancer (2024)

Article

Real-world incidence and risk factors of bortezomib-related cardiovascular adverse events in patients with multiple myeloma

Although most studies on the cardiovascular toxicity of proteasome inhibitors have focused on carfilzomib, the risk of cardiotoxicity associated with bortezomib remains controversial. This study aimed to evalu...

Bitna Jang, Jonghyun Jeong, Kyu-Nam Heo, Youngil Koh, Ju‑Yeun Lee in Blood Research (2024)

Article

Rate of benign histology after resection of suspected renal cell carcinoma: multicenter comparison between Korea and the United States

In the United States, the rate of benign histology among resected renal tumors suspected to be malignant is increasing. We evaluated the rates in the Republic of Korea and assessed the racial effect using rece...

Chang Wook Jeong, Jang Hee Han, Seok Soo Byun, Cheryn Song, Sung-Hoo Hong… in BMC Cancer (2024)

Article

FLI-1 is expressed in a wide variety of hematolymphoid neoplasms: a special concern in the differential diagnosis

Friend Leukemia Virus Integration 1 (FLI-1) is a member of E26 transformation-specific family of transcription factors that participates in hematopoietic and vascular endothelial cell development. Immunohistoc...

Uiju Cho, Hee Jeong Cha, Hyun Jung Kim, Soo Kee Min… in Clinical and Experimental Medicine (2024)

Article

c-MET-positive circulating tumor cells and cell-free DNA as independent prognostic factors in hormone receptor-positive/HER2-negative metastatic breast cancer

Endocrine therapy resistance in hormone receptor-positive/HER2-negative (HR+/HER2−) breast cancer (BC) is a significant clinical challenge that poses several unmet needs in the management of the disease. This ...

Jieun Park, Eun Sol Chang, Ji-Yeon Kim, Chaithanya Chelakkot… in Breast Cancer Research (2024)

Article

Preoperative prediction of early recurrence in resectable pancreatic cancer integrating clinical, radiologic, and CT radiomics features

To use clinical, radiographic, and CT radiomics features to develop and validate a preoperative prediction model for the early recurrence of pancreatic cancer.

Jeong Hyun Lee, Jaeseung Shin, Ji Hye Min, Woo Kyoung Jeong, Honsoul Kim… in Cancer Imaging (2024)

Article

Contrast-enhanced ultrasonography–CT/MRI fusion guidance for percutaneous ablation of inconspicuous, small liver tumors: improving feasibility and therapeutic outcome

Percutaneous radiofrequency ablation (RFA) is pivotal for treating small malignant liver tumors, but tumors often remain inconspicuous on B-mode ultrasound (US). This study evaluates the potential of CEUS-CT/M...

Yuna Lee, Jeong Hee Yoon, Seungchul Han, I** Joo, Jeong Min Lee in Cancer Imaging (2024)

Article

COVID-19-related cardiovascular disease risk due to weight gain: a nationwide cohort study

Cardiovascular disease (CVD) is a significant contributor to morbidity and mortality worldwide, with CVD and post-acute COVID-19 associated CVD increasing. It remains unknown whether COVID-19 patients with wei...

Su Kyoung Lee, Yohwan Lim, Seogsong Jeong… in European Journal of Medical Research (2024)

Article

The RORɣ/SREBP2 pathway is a master regulator of cholesterol metabolism and serves as potential therapeutic target in t(4;11) leukemia

Dysregulated cholesterol homeostasis promotes tumorigenesis and progression. Therefore, metabolic reprogramming constitutes a new hallmark of cancer. However, until today, only few therapeutic approaches exist...

Estelle Erkner, Thomas Hentrich, Rebekka Schairer, Rahel Fitzel… in Oncogene (2024)

Article

Long-term prognostic value of the GenesWell BCT score in Asian women with hormone receptor-positive/HER2-negative early breast cancer

Accurate prediction of the risk of recurrence is crucial for optimal treatment decisions in hormone receptor (HR)-positive/human epidermal growth factor receptor 2 (HER2)-negative early breast cancer. The Gene...

Yoshitaka Fujiki, Masahiro Kashiwaba, Mutsumi Sato, Junko Kawano… in Breast Cancer (2024)

Article

Endosulfine alpha maintains spindle pole integrity by recruiting Aurora A during mitosis

The maintenance of spindle pole integrity is essential for spindle assembly and chromosome segregation during mitosis. However, the underlying mechanisms governing spindle pole integrity remain unclear.

Seul Kim, Kyoungho Jun, Ye-Hyun Kim, Kwan-Young Jung, Jeong Su Oh… in BMC Cancer (2023)

Article

Pancreas CT assessment for pancreatic ductal adenocarcinoma resectability: effect of tube voltage and slice thickness on image quality and diagnostic performance

To assess the resectability of pancreatic ductal adenocarcinoma (PDAC), the evaluation of tumor vascular contact holds paramount significance. This study aimed to compare the image quality and diagnostic perfo...

Dong Ho Lee, Seung Soo Lee, Jeong Min Lee, **-Young Choi, Chang Hee Lee… in Cancer Imaging (2023)

Article

PSMD1 as a prognostic marker and potential target in oropharyngeal cancer

Despite the diverse genetic mutations in head and neck cancer, the chemotherapy outcome for this cancer has not improved for decades. It is urgent to select prognostic factors and therapeutic targets for oroph...

Hae Chan Park, Hyo** Kim, Ji-Yeong Kim, Hye-Yeon Lee, **yi Lee, WonJae Cha… in BMC Cancer (2023)

Article

Safety and efficacy of a novel anti-CD19 chimeric antigen receptor T cell product targeting a membrane-proximal domain of CD19 with fast on- and off-rates against non-Hodgkin lymphoma: a first-in-human study

Commercial anti-CD19 chimeric antigen receptor T-cell therapies (CART19) are efficacious against advanced B-cell non-Hodgkin lymphoma (NHL); however, most patients ultimately relapse. Several mechanisms contri...

Yunlin Zhang, Ruchi P. Patel, Ki Hyun Kim, Hyungwoo Cho, Jae-Cheol Jo… in Molecular Cancer (2023)

Article

Correction: Cancer organoid-based diagnosis reactivity prediction (CODRP) index-based anticancer drug sensitivity test in ALK-rearrangement positive non-small cell lung cancer (NSCLC)

Sang-Yun Lee, Hyeong Jun Cho, Jimin Choi… in Journal of Experimental & Clinical Cancer … (2023)

Article

Targeting PEG10 as a novel therapeutic approach to overcome CDK4/6 inhibitor resistance in breast cancer

Breast cancer is the global leading cancer burden in women and the hormone receptor-positive (HR+) subtype is a major part of breast cancer. Though cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors are highl...

Nar Bahadur Katuwal, Min Sil Kang… in Journal of Experimental & Clinical Cancer … (2023)

Article

Cancer organoid-based diagnosis reactivity prediction (CODRP) index-based anticancer drug sensitivity test in ALK-rearrangement positive non-small cell lung cancer (NSCLC)

Recently, cancer organoid-based drug sensitivity tests have been studied to predict patient responses to anticancer drugs. The area under curve (AUC) or IC₅₀ value of the dose-response curve (DRC) is used to diff...

Sang-Yun Lee, Hyeong Jun Cho, Jimin Choi… in Journal of Experimental & Clinical Cancer … (2023)

Article

Artificial intelligence-powered spatial analysis of tumor-infiltrating lymphocytes for prediction of prognosis in resected colon cancer

Tumor-infiltrating lymphocytes (TIL) have been suggested as an important prognostic marker in colorectal cancer, but assessment usually requires additional tissue processing and interpretational efforts. The a...

Yoojoo Lim, Songji Choi, Hyeon Jeong Oh, Chanyoung Kim… in npj Precision Oncology (2023)

Article

Prognostic impact of pretreatment skeletal muscle index and CONUT score in diffuse large B-cell Lymphoma

Although the prognostic value of the Controlling Nutritional Status (CONUT) score in diffuse large B-cell lymphoma (DLBCL) has been reported in several previous studies, its clinical relevance for the presence...

Se-Il Go, Bong-Hoi Choi, Mi Jung Park, Sungwoo Park, Myoung Hee Kang… in BMC Cancer (2023)

Article

Effects of resection volume on postoperative micturition symptoms and retreatment after transurethral resection of the prostate

Despite advances in technology, such as advent of laser enucleation and minimally invasive surgical therapies, transurethral resection of the prostate (TURP) remains the most widely performed surgical techniqu...

Seung Han Shin, Kwang Suk Lee, Kyo Chul Koo, Kang Su Cho… in World Journal of Urology (2023)