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  1. Article

    Open Access

    Chronic prostatitis alters the prostatic microenvironment and accelerates preneoplastic lesions in C57BL/6 mice

    Chronic prostatitis has been supposed to be associated with preneoplastic lesions and cancer development. The objective of this study was to examine how chronic inflammation results in a prostatic microenviron...

    Yong Gao, Lijuan Wei, Chenbang Wang, Yuanjie Huang, Weidong Li in Biological Research (2019)

  2. No Access

    Article

    Genome-wide screening of hexokinase gene family and functional elucidation of HXK2 response to cold stress in Jatropha curcas

    Hexokinase, the key rate-limiting enzyme of plant respiration and glycolysis metabolism, has been found to play a vital role in plant sugar sensing and sugar signal transduction. Using Jatropha curcas genome data...

    Haibo Wang, Hu **n, Junyun Guo, Yong Gao, Chao Liu in Molecular Biology Reports (2019)

  3. No Access

    Article

    The phytochrome-interacting family of transcription factors in maize (Zea mays L.): identification, evolution, and expression analysis

    The phytochrome-interacting factor (PIF) subfamily of transcription factors is among the most important families of plant transcriptional regulators. PIFs regulate multiple biological processes, especially the...

    Yong Gao, **aoyun Ren, **gjie Qian, Qian Li, Haixia Tao in Acta Physiologiae Plantarum (2019)

  4. No Access

    Article

    Effects of chilling stress on the accumulation of soluble sugars and their key enzymes in Jatropha curcas seedlings

    As osmolytes and signaling molecules, soluble sugars participate in the response and adaptation of plants to environmental stresses. In the present study, we measured the effect of chilling (12 °C) stress on t...

    Haibo Wang, Ming Gong, Hu **n, Lizhou Tang in Physiology and Molecular Biology of Plants (2018)

  5. No Access

    Article

    Differential influence of elevated CO2 on gas exchange and water use efficiency of four indigenous shrub species distributed in different sandy environments in central Inner Mongolia

    In view of the increase in global warming and carbon dioxide (CO2) concentrations, it is essential to investigate the influences of climate change on plant growth and water use in arid and semi-arid grassland spe...

    Qiaoyan Li, Liming Lai, Jihua Zhou, Hui Du, Tianyu Guan in Ecological Research (2018)

  6. No Access

    Article

    Roles of a maize phytochrome-interacting factors protein ZmPIF3 in regulation of drought stress responses by controlling stomatal closure in transgenic rice without yield penalty

    ZmPIF3 plays an important role in ABA-mediated regulation of stomatal closure in the control of water loss, and can improve both drought tolerance and did not affect the grain yield in the transgenic rice.

    Yong Gao, Meiqin Wu, Menjiao Zhang, Wei Jiang, Enxing Liang in Plant Molecular Biology (2018)

  7. No Access

    Article

    Seaward migration behavior of juvenile second filial generation Chinese sturgeon Acipenser sinensis in the Yangtze River, China

    Second filial generation (F2) Chinese sturgeon from hatcheries have been released to restock the endangered natural population of this fish ever since full-cycle artificial breeding was first achieved in 2009....

    Chuan Wu, Lei Chen, Yong Gao, Wei Jiang in Fisheries Science (2018)

  8. No Access

    Article

    Retinoic acid ameliorates high-fat diet-induced liver steatosis through sirt1

    In this study, treatment of C57BL/6J (wild type, WT) mice fed a high-fat diet (HFD) with retinoic acid (RA) decreased body weight and subcutaneous and visceral fat content, reversed the apparent hepatosteatosi...

    Chao Geng, Haifeng Xu, Yinliang Zhang, Yong Gao, Meixia Li in Science China Life Sciences (2017)

  9. No Access

    Article

    Characterizing vertical migration of Microcystis aeruginosa and conditions for algal bloom development based on a light-driven migration model

    Light-driven vertical migration is critical in dense aggregation of Microcystis aeruginosa during algal blooms under reduced turbulence conditions in natural water bodies. This study examined the vertical migrati...

    Bo Yao, Qingquan Liu, Yong Gao, Zhixian Cao in Ecological Research (2017)

  10. Article

    Open Access

    Transplanted human p75-positive stem Leydig cells replace disrupted Leydig cells for testosterone production

    Previous studies have demonstrated that rodent stem Leydig cell (SLC) transplantation can partially restore testosterone production in Leydig cell (LC)-disrupted or senescent animal models, which provides a pr...

    Min Zhang, Jiancheng Wang, Chunhua Deng, Mei Hua Jiang, **n Feng in Cell Death & Disease (2017)

  11. Article

    Open Access

    IAPP modulates cellular autophagy, apoptosis, and extracellular matrix metabolism in human intervertebral disc cells

    The pathogenic process of intervertebral disc degeneration (IDD) is characterized by imbalance in the extracellular matrix (ECM) metabolism. Nucleus pulposus (NP) cells have important roles in maintaining the ...

    **nghuo Wu, Yu Song, Wei Liu, Kun Wang, Yong Gao, Shuai Li in Cell Death Discovery (2017)

  12. Article

    Open Access

    PredPhos: an ensemble framework for structure-based prediction of phosphorylation sites

    Post-translational modifications (PTMs) occur on almost all proteins and often strongly affect the functions of modified proteins. Phosphorylation is a crucial PTM mechanism with important regulatory functions...

    Yong Gao, Weilin Hao, **g Gu, Diwei Liu in Journal of Biological Research-Thessaloniki (2016)

  13. No Access

    Article

    Downregulation and tumor-suppressive role of XPO5 in hepatocellular carcinoma

    XPO5 (Exp5, Exportin-5) is a transporter protein mainly mediating pre-microRNAs’ nuclear export. Recent studies have demonstrated that XPO5 may play crucial roles in a few of cancers. However, little is known ...

    Yandong Li, **ao Wang, Bin He, Hui Cai, Yong Gao in Molecular and Cellular Biochemistry (2016)

  14. No Access

    Article

    A FOXM1 related long non-coding RNA contributes to gastric cancer cell migration

    Long non-coding RNAs (LncRNAs) have been reported that play important roles in the progression and metastasis of some carcinomas. In the present study, we identified a new LncRNA, FRLnc1, from a microarray ana...

    Hui Cai, **gde Chen, Bin He, Qiang Li, Yandong Li in Molecular and Cellular Biochemistry (2015)

  15. No Access

    Article

    MicroRNA expression profiles in conventional and micropropagated Dendrobium officinale

    MicroRNA (miRNA) is defined as an endogenous ~22 nt noncoding RNA that has critical gene-regulatory functions in plants. Dendrobium officinale is among the most important herbs in traditional Chinese medicine. Ho...

    Zhili Yang, Dongfeng Yang, **anfeng Ding, Yong Gao, Donghai Li, Tao Xu in Genes & Genomics (2015)

  16. No Access

    Article

    A maize phytochrome-interacting factor 3 improves drought and salt stress tolerance in rice

    Phytochrome-interacting factor 3 (PIF3) activates light-responsive transcriptional network genes in coordination with the circadian clock and plant hormones to modulate plant growth and development. However, ...

    Yong Gao, Wei Jiang, Yi Dai, Ning **ao, Changquan Zhang, Hua Li in Plant Molecular Biology (2015)

  17. Article

    Open Access

    Association study of stuttering candidate genes GNPTAB, GNPTG and NAGPA with dyslexia in Chinese population

    Dyslexia is a polygenic speech and language disorder characterized by an unexpected difficulty in reading in children and adults despite normal intelligence and schooling. Increasing evidence reveals that diff...

    Huan Chen, Junquan Xu, Yuxi Zhou, Yong Gao, Guoqing Wang, Jiguang **a in BMC Genetics (2015)

  18. No Access

    Article

    Fine map** of the qLOP2 and qPSR2-1 loci associated with chilling stress tolerance of wild rice seedlings

    Using leaf osmotic potential and plant survival rate as chilling-tolerant trait indices, we identified two major quantitative trait loci qLOP2 and ...

    Ning **ao, Wei-nan Huang, Ai-hong Li, Yong Gao in Theoretical and Applied Genetics (2015)

  19. No Access

    Article

    Effects and Mechanism Analysis of Vascular Endothelial Growth Factor and Salvianolic Acid B on 125I-Low Density Lipoprotein Permeability of the Rabbit Aortary Endothelial Cells

    Atherosclerosis is the common pathological basis of cardiovascular and cerebrovascular disease. This study aimed to investigate the effects of vascular endothelial growth factor (VEGF) and salvianolic acid B (...

    Jianming Ba, Hu Peng, Yanqing Chen, Yong Gao in Cell Biochemistry and Biophysics (2014)

  20. Article

    Open Access

    Characterization of Nestin-positive stem Leydig cells as a potential source for the treatment of testicular Leydig cell dysfunction

    The ability to identify and isolate lineage-specific stem cells from adult tissues could facilitate cell replacement therapy. Leydig cells (LCs) are the primary source of androgen in the mammalian testis, and ...

    Mei Hua Jiang, Bing Cai, Ying Tuo, Jiancheng Wang, Zhi Jun Zang in Cell Research (2014)

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