209 Result(s)

Article

Retraction Note: Periostin secreted by cancer-associated fibroblasts promotes cancer stemness in head and neck cancer by activating protein tyrosine kinase 7

Binbin Yu, Kailiu Wu, Xu Wang, Jianjun Zhang, Lizhen Wang… in Cell Death & Disease (2024)

Article

Author Correction: Metformin potentiates nephrotoxicity by promoting NETosis in response to renal ferroptosis

Zhaoxian Cai, **aotian Wu, Zijun Song, Shumin Sun, Yunxing Su… in Cell Discovery (2024)

Article

A cell model for evaluating mitochondrial damage in cardiomyocytes

Various cellular models were used for assessment of mitochondrial damage in cardiomyocyte, but most of them are based on silent cells without contractility. The mitochondria in cells at working should be more ...

Yingying Zhang, Yongxue Chen, Senming Zhao in Molecular & Cellular Toxicology (2024)

Article

A missense mutant of ocrl1 promotes apoptosis of tubular epithelial cells and disrupts endocytosis and the cell cycle of podocytes in Dent-2 Disease

This study aimed to identify an orcl1 mutation in a patient with Dent-2 Disease and investigate the underlying mechanisms.

Limin Huang, Yingying Zhang, Haidong Fu, Weizhong Gu… in Cell Communication and Signaling (2023)

Article

Immunity-and-matrix-regulatory cells enhance cartilage regeneration for meniscus injuries: a phase I dose-escalation trial

Immunity-and-matrix-regulatory cells (IMRCs) derived from human embryonic stem cells have unique abilities in modulating immunity and regulating the extracellular matrix, which could be mass-produced with stab...

Liangjiang Huang, Song Zhang, Jun Wu… in Signal Transduction and Targeted Therapy (2023)

Article

KLHL29-mediated DDX3X degradation promotes chemosensitivity by abrogating cell cycle checkpoint in triple-negative breast cancer

Triple-negative breast cancer (TNBC) is a heterogeneous breast cancer subtype and accounts for approximately 15–20% of breast cancer cases. In this study, we identified KLHL29, which is an understudied member ...

Litong Yao, Qian Hao, Mozhi Wang, Yuhai Chen, Hongyi Cao, Qiang Zhang, Keda Yu… in Oncogene (2023)

Article

Metformin potentiates nephrotoxicity by promoting NETosis in response to renal ferroptosis

Given the rapidly aging population, aging-related diseases are becoming an excessive burden on the global healthcare system. Metformin has been shown to be beneficial to many age-related disorders, as well as ...

Zhaoxian Cai, **aotian Wu, Zijun Song, Shumin Sun, Yunxing Su… in Cell Discovery (2023)

Article

Macrophages originated IL-33/ST2 inhibits ferroptosis in endometriosis via the ATF3/SLC7A11 axis

Endometriosis is a gynecological inflammatory disease that is linked with immune cells, specifically macrophages. IL-33 secreted from macrophages is known to accelerate the progression of endometriosis. The pe...

Qiong Wu, Zongwen Liang, **g Jiang, **aoming Feng, **ming Liu… in Cell Death & Disease (2023)

Article

Crotonylated BEX2 interacts with NDP52 and enhances mitophagy to modulate chemotherapeutic agent-induced apoptosis in non-small-cell lung cancer cells

Brain expressed X-linked gene 2 (BEX2) encoded protein was originally identified to promote transcription by interacting with several transcription factors in the DNA–binding complexes. Recently, BEX2 was found t...

Ning Mu, Yu Wang, **aopeng Li, Zhiyuan Du, Yingdi Wu, Min Su… in Cell Death & Disease (2023)

Article

PPM1K mediates metabolic disorder of branched-chain amino acid and regulates cerebral ischemia-reperfusion injury by activating ferroptosis in neurons

Ischemic stroke is a neurological disorder caused by vascular stenosis or occlusion, accounting for approximately 87% of strokes. Clinically, the most effective therapy for ischemic stroke is vascular recanali...

Tao Li, Lili Zhao, Ye Li, Meijuan Dang, Jialiang Lu, Ziwei Lu… in Cell Death & Disease (2023)

Article

The functional effects of Piezo channels in mesenchymal stem cells

Mesenchymal stem cells (MSCs) are widely used in cell therapy, tissue engineering, and regenerative medicine because of their self-renewal, pluripotency, and immunomodulatory properties. The microenvironment i...

Zhilong Huang, Yingying Huang, **ner Ning, Haodi Li… in Stem Cell Research & Therapy (2023)

Article

Haspin balances the ratio of asymmetric cell division through Wnt5a and regulates cell fate decisions in mouse embryonic stem cells

Many different types of stem cells utilize asymmetric cell division (ACD) to produce two daughter cells with distinct fates. Haspin-catalyzed phosphorylation of histone H3 at Thr3 (H3T3ph) plays important role...

Yingying Gao, Bin Ma, Yifan Li, **angyu Wu, Shifeng Zhao… in Cell Death Discovery (2023)

Article

Retraction Note: Histone methyltransferase SUV39H2 regulates LSD1-dependent CDH1 expression and promotes epithelial mesenchymal transition of osteosarcoma

Yingying Miao, Guifeng Liu, Lin Liu in Cancer Cell International (2023)

Article

Standard: Human intestinal cancer organoids

Intestinal cancer is one of the most frequent and lethal types of cancer. Modeling intestinal cancer using organoids has emerged in the last decade. Human intestinal cancer organoids are physiologically releva...

Hanqing Lin, Yalong Wang, Chunyan Cheng, Yuxin Qian, Jie Hao… in Cell Regeneration (2023)

Article

Emerging roles of ferroptosis-related miRNAs in tumor metastasis

Ferroptosis, a novel mode of cell death dependent on iron and reactive oxygen species, has been extensively explored during malignant tumors metastasis. Ferroptosis can interact with multiple components of the...

Zhongyi Jiang, **g Zhou, Junqi Deng, Luohong Li, Ruifeng Wang… in Cell Death Discovery (2023)

Article

A neonatal rat model of pulmonary vein stenosis

Pulmonary vein stenosis (PVS), one of the most challenging clinical problems in congenital heart disease, leads to secondary pulmonary arterial hypertension (PAH) and right ventricular (RV) hypertrophy. Due to...

Debao Li, Lisheng Qiu, Haifa Hong, Hao Chen, Peibin Zhao… in Cell & Bioscience (2023)

Article

TOPK promotes the growth of esophageal cancer in vitro and in vivo by enhancing YB1/eEF1A1 signal pathway

T-LAK-originated protein kinase (TOPK), a dual specificity serine/threonine kinase, is up-regulated and related to poor prognosis in many types of cancers. Y-box binding protein 1 (YB1) is a DNA/RNA binding pr...

Wenjie Wu, Jialuo Xu, Dan Gao, Zhenliang **e, Wen**g Chen… in Cell Death & Disease (2023)

Article

Standard: Human intestinal organoids

Organoids have attracted great interest for disease modelling, drug discovery and development, and tissue growth and homeostasis investigations. However, lack of standards for quality control has become a prom...

Yalong Wang, Hanqing Lin, Lianzheng Zhao, Fan Hong, Jie Hao… in Cell Regeneration (2023)

Article

TMT-based quantitative proteomic analysis of spheroid cells of endometrial cancer possessing cancer stem cell properties

Cancer stem cells (CSCs) play an important role in endometrial cancer progression and it is potential to isolate CSCs from spheroid cells. Further understanding of spheroid cells at protein level would help fi...

Mingzhu Cao, Zhi Liu, Danming You, Yingying Pan… in Stem Cell Research & Therapy (2023)

Article

Aminoprocalcitonin protects against hippocampal neuronal death via preserving oxidative phosphorylation in refractory status epilepticus

Refractory status epilepticus (RSE) is a neurological emergency where sustaining seizure causes severe neuronal death. Currently, there is no available neuroprotectant effective in RSE. Aminoprocalcitonin (NPC...

Changgeng Song, **g**g Zhao, Jianmin Hao, Dan Mi, Jiajia Zhang… in Cell Death Discovery (2023)