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Article
Regression zerebraler Posttransplantationslymphome unter Cyclosporin-A-Reduktion
4.5 months after successfull kidney transplantation a Non-Hodgkin-lymphoma with polymorph centroblastic appearance of the tonsillar gland developed in a 21 years old male patient during immunosuppressive thera...
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Chapter
Progressive multifokale Leukenzephalopathie — Klinische, radiologische, histologische Befunde und molekularbiologische Sicherung der Diagnose
Besondere neuropathologische Merkmale grenzten die progressive multifokale Leukenzephalopathie (PML) 1958 gegen andere Enzephalopathien ab [1]: Typischerweise sind Läsionen zu erkennen, die sich aus meist mult...
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Article
Short-term inhibition of cellular autophagy by isoproterenol in the submandibular gland
The present study examines the shortterm (i.e. 10 min after injection) influence of isoproterenol on cellular autophagy in the rat submandibular gland. The volume fraction of autophagic vacuoles was significan...
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Article
Inhibited autophagic degradation during ACTH-stimulated growth of rat adrenal zona fasciculata
Autophagic vacuoles (AVs) in adrenal parenchymal cells of the outer part of the zona fasciculata were investigated by means of electron microscopic morphometry in 40 adult male Spraque Dawley rats. Four test g...
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Chapter and Conference Paper
Intracellular turnover and cardiac hypertrophy
Ultrastructural evidence is presented that intracellular autophagic degradation of cytoplasmic constituents is reduced during perssure induced hypertropy of left ventricular myocardium after supravalvular aort...
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Chapter
Intrazellulärer Turnover bei druckinduzierter Herzhypertrophie
Wenn von Herzhypertrophie die Rede ist, so meint man für gewöhnlich einen Zustand, nämlich den der über die Norm hinaus vermehrten Herzmuskelmasse. Im Vordergrund des Interesses stehen dann naturgemäß diejenigen ...
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Article
225. Experimentelle Untersuchungen über respiratorische Komplikationen bei der akuten Pankreatitis
The model of taurocholate-induced acute hemorrhagic pancreatitis in the rat was used to investigate the effects of this disease on the respiratory system. After induction (4 and 24 h) there was a decrease in p...
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Article
Ascites als Komplikation hepatischer Speicherung von Hydroxyethylstärke (HES) bei Langzeitdialyse
Three adult dialysis patients developed ascites after having received repeatedly the plasma substitue hydroxyethyl starch (HES 40/0.5). In two cases (total dose 180, and 330 g HES, respectively) the ascites wa...
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Article
Cardiac hypertrophy in rats after supravalvular aortic constriction
The ascending aorta of 22 adult male Sprague-Dawley rats was constricted with a silver ring, and 25 animals were subjected to a sham-operation. The hearts, including the main arteries, were fixed by retrograde...
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Article
Cardiac hypertrophy in rats after supravalvular aortic constriction
Adult male Sprague-Dawley rats were killed by retrograde perfusion fixation 3, 7, 14, 21 and 35 days after supravalvular aortic constriction (n = 33) or sham-operation (n = 25). Subepicardial specimens of the lef...
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Chapter
Ultrastructural Pathology of the Human Liver
As early as the mid-sixties it could be recognized from the first surveys on electron microscopy of human liver tissue (Cossel 1964, Hübner 1968, Tanikawa 1968) that the increase in knowledge regarding the pat...
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Article
To the 65th birthday of Hans-Werner Altman
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Article
Hepatocellular fibrinogen storage in familial hypofibrinogenemia
In the cytoplasm of hepatocytes of liver biopsy from a 30 year old man, there were proteinaceous inclusions which by use of the peroxidaseantiperoxidase method reacted strongly with antihuman-fibrinogen IgG, b...
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Article
Acute effects of isoproterenol on cellular autophagy
The influence of isoproterenol (IPR) on cellular autophagy was examined in left ventricular myocardium and in liver parenchyma of rats two hours after a subcutaneous injection of a low dose (3 mg/kg body weigh...
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Article
A simple method for incubation of tissue sections in immunohistochemistry
The construction of a simple “incubatin chamber” is presented by which a homogeneous incubation of tissue sections with calculable amounts of immunoreagents is guaranteed. The incubation of large area sections...
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Article
Experimental non-A, non-B hepatitis: four types of cytoplasmic alteration in hepatocytes of infected chimpanzees
On the occasion of an outbreak of non-A, non-B hepatitis in a plasmapheresis centre (81 cases, incubation period: 3–6 weeks) a pool of 12 plasma samples was obtained in the early phase of increasing transamina...
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Article
A morphometric study on growth of bile canaliculi after partial hepatectomy
19–33 h after partial hepatectomy there is a time-dependent increase of the bile canalicular luminal volume, of the total length of bile canaliculi, and of their non-microvillous, smooth surface, when measured...
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Article
Cholesterylester-Speicherkrankheit
Hepatomegaly and a slight to moderate elevation of serum transaminases were detected in four children (three boys two of whom were siblings, and one girl) at the age of 4–6 years. The clinical course was follo...
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Chapter and Conference Paper
Prospektive kooperative Studie „Klinisch gesunde HBsAg-Träger“ (DFG)
Motiv für die 1972 begonnene kooperative DFG-Studie „Klinisch gesunde HBsAg-Träger“ war die damals ganz ungewisse Prognose dieses Personenkreises, die in Korrelation zu virusserologischen Parametern durch eine...
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Chapter and Conference Paper
Kooperative prospektive Studie „Akute Virushepatitis“ (DFG)
Motiv für die 1972 begonnene prospektive DFG-Studie „Akute Virushepatitis“ war ursprünglich die Abklärung der diagnostischen und prognostischen Bedeutung des ersten HBV-Markers, des Australia-Antigen (= HBsAg)...
