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  1. No Access

    Chapter

    Combination by Hyperthermia and Radiation and Chemotherapy: Soft Tissue Sarcoma

    Soft tissue sarcoma is an extremely rare disease with an annual incidence of 3 per 100,000 people, accounting for 1 % or less of all malignant tumors. High-grade soft tissue sarcoma requires multidisciplinary ...

    Hisaki Aiba, Hiroaki Kimura, Takanobu Otsuka in Hyperthermic Oncology from Bench to Bedside (2016)

  2. No Access

    Article

    Quantitative analysis of attachment of the labrum to the glenoid fossa: a cadaveric study

    This study investigated the direct and continuous attachment of the labrum to the glenoid fossa, including the fibrocartilaginous tissue, using image-analysis software and histology.

    Masahito Yoshida, Hideyuki Goto, Masahiro Nozaki in Journal of Orthopaedic Science (2015)

  3. No Access

    Article

    Postoperative evaluation of drill holes for arthroscopic Bankart repair with suture anchors by the use of computed tomography

    Here we investigated the angle and placement of bone holes for suture anchors using postoperative computed-tomography scapula scans.

    Masahito Yoshida, Hideyuki Goto, Masahiro Nozaki in Journal of Orthopaedic Science (2015)

  4. No Access

    Article

    Is the canal flare index a reliable means of estimation of canal shape? Measurement of proximal femoral geometry by use of 3D models of the femur

    The canal flare index (CFI; the ratio of the diameter of the femoral canal at the isthmus in the anteroposterior (A–P) view to the diameter of the medullary canal 20 mm above the lesser trochanter) is often us...

    Kaneaki Tawada, Hirotaka Iguchi, Nobuhiko Tanaka in Journal of Orthopaedic Science (2015)

  5. Article

    Significance of serum Zn-α2-glycoprotein for the regulation of blood pressure

    Zn-α2-glycoprotein (ZAG) (molecular weight=41 kDa) is one component in the α2 fraction of human plasma, and is reported to be associated with several diseases, such as cancers and metabolic syndromes. ZAG is a...

    Souichi Kurita, Keisuke Takeuchi, Yoshimi Hayashi, Hisao Ueyama in Hypertension Research (2015)

  6. Article

    Open Access

    Corrective surgery for Parkinson's disease (PD) deformity following Deep Brain Stimulation (DBS) - Is DBS a last resort?

    Jun Mizutani, Muneyoshi Fukuoka, Nobuyuki Suzuki, Seiji Otsuka in Scoliosis (2015)

  7. No Access

    Article

    Ultrasound imaging of the humeral capitellum: a cadaveric study

    Ultrasound is suitable for routine examinations of capitellar osteochondritis dissecans because it can visualize both the subchondral bone and the overlying articular cartilage non-invasively. The radial head ...

    Tetsuya Takenaga, Hideyuki Goto, Masahiro Nozaki in Journal of Orthopaedic Science (2014)

  8. No Access

    Article

    Diagnosis and treatment of low-grade osteosarcoma: experience with nine cases

    Low-grade osteosarcoma, including low-grade central osteosarcoma and parosteal osteosarcoma, is an extremely rare variant, and the diagnosis is occasionally difficult. In this article we present cases of low-g...

    Katsuhiro Hayashi, Hiroyuki Tsuchiya in International Journal of Clinical Oncology (2014)

  9. No Access

    Chapter

    Evaluation of the Reputation Network Using Realistic Distance Between Facebook Data

    In recent years, such SNS services as Facebook, Google+, and Twitter have become very popular. In such services, many sources of information are posted and shared, although user rankings are hardly considered....

    Takanobu Otsuka, Takuya Yoshimura in Novel Insights in Agent-based Complex Auto… (2014)

  10. Article

    Open Access

    Induced pluripotent stem cells from patients with human fibrodysplasia ossificans progressiva show increased mineralization and cartilage formation

    Abnormal activation of endochondral bone formation in soft tissues causes significant medical diseases associated with disability and pain. Hyperactive mutations in the bone morphogenetic protein (BMP) type 1 ...

    Yoshihisa Matsumoto, Yohei Hayashi in Orphanet Journal of Rare Diseases (2013)

  11. Article

    Open Access

    The Pavlik harness in the treatment of developmentally dislocated hips: results of Japanese multicenter studies in 1994 and 2008

    It has already been more than 50 years since the Pavlik harness was introduced in Japan, and today the Pavlik harness is widely recognized as the standard initial treatment modality for developmental dysplasia...

    Ikuo Wada, Eisuke Sakuma, Takanobu Otsuka in Journal of Orthopaedic Science (2013)

  12. Article

    Open Access

    Flexible WSNs Aims Easy Installation With Noise Reduce Method For Elderly People Care

    Much research has been conducted on anomaly detection by wireless sensor networks (WSNs). The existing WSNs require specialized knowledge and skills to install the sensors in environments such as houses and bu...

    Takanobu Otsuka, Takayuki Ito in International Journal of Networked and Dis… (2013)

  13. No Access

    Chapter and Conference Paper

    Prototy** and Evaluation of a Wireless Sensor Network That Aims Easy Installation

    The number of senior citizens living alone are increasing in Japan. Accordingly, the budget for social security is increasing. The percentage of burden for social security budgets reached 69.5% only for senior...

    Takanobu Otsuka, Tatsunosuke Tsuboi in Contemporary Challenges and Solutions in A… (2013)

  14. Article

    Open Access

    The ikyoku system of university orthopedic surgery departments: an in-hospital organizational system unique to Japan—its significance for advancement of basic medical science related to orthopedic surgery

    Takanobu Otsuka in Journal of Orthopaedic Science (2012)

  15. Article

    Open Access

    The Sp1 transcription factor is essential for the expression of gliostatin/thymidine phosphorylase in rheumatoid fibroblast-like synoviocytes

    Gliostatin/thymidine phosphorylase (GLS/TP) has angiogenic and arthritogenic activities, and aberrant GLS production has been observed in the active synovial membranes of rheumatoid arthritis (RA) patients. Th...

    Kenji Ikuta, Yuko Waguri-Nagaya, Kae Kikuchi in Arthritis Research & Therapy (2012)

  16. No Access

    Article

    Anatomical features of the pronator quadratus muscle related to minimally invasive plate osteosynthesis of distal radial fractures with a volar locking plate: a cadaver study

    The purpose of this study was to determine the anatomical features of the pronator quadratus muscle related to minimally invasive plate osteosynthesis for distal radius fractures.

    Naoya Takada, Takanobu Otsuka in European Orthopaedics and Traumatology (2011)

  17. No Access

    Article

    Minimally invasive osteosynthesis with an intramedullary nail for osteoporotic distal radius fractures

    Since 2006, the authors have been using minimally invasive osteosynthesis with an intramedullary nail (MICRONAIL; Wright Medical Technologies, Arlington, TN) for treating osteoporotic distal radius fractures. ...

    Naoya Takada, Takanobu Otsuka, Akira Kondo in European Journal of Orthopaedic Surgery & … (2011)

  18. Article

    Open Access

    Prostaglandin E2 receptor type 2-selective agonist prevents the degeneration of articular cartilage in rabbit knees with traumatic instability

    Osteoarthritis (OA) is a common cause of disability in older adults. We have previously reported that an agonist for subtypes EP2 of the prostaglandin E2 receptor (an EP2 agonist) promotes the regeneration of ...

    Hiroto Mitsui, Tomoki Aoyama, Moritoshi Furu, Kinya Ito in Arthritis Research & Therapy (2011)

  19. No Access

    Article

    FK506 inhibition of gliostatin/thymidine phosphorylase production induced by tumor necrosis factor-α in rheumatoid fibroblast-like synoviocytes

    Gliostatin/thymidine phosphorylase (GLS/TP) is known to have angiogenic and arthritogenic activities. The purpose of this study was to determine the inhibitory effects of FK506 (tacrolimus) on GLS production i...

    Takaya Yamagami, Yuko Waguri-Nagaya, Kenji Ikuta in Rheumatology International (2011)

  20. Article

    Open Access

    Validation of radiographic response evaluation criteria of preoperative chemotherapy for bone and soft tissue sarcomas: Japanese Orthopaedic Association Committee on Musculoskeletal Tumors Cooperative Study

    The radiographic evaluation of the response to preoperative chemotherapy for bone and soft tissue sarcomas is based mostly on the change in primary tumor size before and after chemotherapy, as is done for many...

    Takafumi Ueda, Norifumi Naka, Nobuhito Araki in Journal of Orthopaedic Science (2008)

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