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  1. No Access

    Article

    Synthesis and bioevaluation of a 177Lu-labeled unsymmetrical cationic porphyrin derivative as a tumor targeting agent

    A cationic porphyrin derivative namely, 5-carboxymethyleneoxyphenyl-10,15,20-tri(p-N-methylpyridyl)porphyrin was synthesized and conjugated with a bi-functional chelating agent namely, p-NH2-benzyl-DOTA (p-aminob...

    Mohini Guleria, Tapas Das… in Journal of Radioanalytical and Nuclear Che… (2016)

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    Article

    Neutral 99mTc(CO)3 complexes of “clicked” nitroimidazoles for the detection of tumor hypoxia

    In the present work, three neutral 99mTc(CO)3 complexes of nitroimidazole were synthesized and their potential to detect tumor hypoxia is evaluated in vivo. Triazole derivatives of 2-, 4- and 5-nitroimidazole wer...

    Mohini Bhadwal, Madhava B. Mallia… in Journal of Radioanalytical and Nuclear Che… (2016)

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    Article

    Radiosynthesis and Bioevaluation of [68Ga]-Labeled 5,10,15,20-Tetra(4-methylpyridyl)-porphyrin for Possible Application as a PET Radiotracer for Tumor Imaging

    Porphyrins have inherent ability to localize preferentially in tumor lesions. Cationic porphyrins are readily water soluble and reported to exhibit strong DNA-binding capabilities. Therefore, attempt has been ...

    Mohini Bhadwal, Tapas Das, Haladhar Dev Sarma… in Molecular Imaging and Biology (2015)

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    Article

    Formulation and radiochemical evaluation of a freeze-dried mixed peptide kit for the preparation of 68Ga-labeled peptides for PET imaging of somatostatin receptor positive neuroendocrine cancers

    68Ga-labeled DOTA-coupled somatostatin analogue peptides are regularly being used for the PET imaging of patients suspected to be suffering from various types of neuroendocrine cancers over-expre...

    Tapas Das, Mohini Bhadwal, H. D. Sarma… in Journal of Radioanalytical and Nuclear Che… (2014)

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    Article

    Synthesis and evaluation of a phenylbenzothiazole-based 99mTc(CO)3-radiotracer for possible application in imaging of β-amyloid plaques in Alzheimer’s disease

    The 2-phenyl benzothiazole pharmacophore is known to have high affinity for amyloid beta (Aβ) and is therefore derivatized, to [N-(4′-benzothiazol-pyridin-2-yl-methyl-amino)-acetic acid (BTPAA)] for radiolabeling...

    Drishty Satpati, Aruna Korde, H. D. Sarma… in Journal of Radioanalytical and Nuclear Che… (2014)

  6. No Access

    Article

    Preparation of DOTA-TATE and DOTA-NOC freeze-dried kits for formulation of patient doses of 177Lu-labeled agents and their comparison for peptide receptor radionuclide therapy application

    The objective of the present work is to prepare freeze-dried DOTA-TATE and DOTA-NOC kits for the easy and convenient preparation of patient doses of 177Lu-DOTA-TATE and 177Lu-DOTA-NOC, respectively at the hospita...

    Tapas Das, Mohini Bhadwal, Sharmila Banerjee… in Journal of Radioanalytical and Nuclear Che… (2014)

  7. No Access

    Article

    Radiosynthesis and in vitro evaluation of 99mTc(CO)3-labeled folic acid derivative

    The over-expression of folate receptors in variety of neoplastic tissues makes radiolabeled folate conjugates potential agents for imaging and therapy of such cancers. With the aim of preparing an imaging agen...

    Drishty Satpati, Archana Mukherjee… in Journal of Radioanalytical and Nuclear Che… (2011)

  8. No Access

    Article

    Albright’s hereditary osteodystrophy

    Albright’s hereditary osteodystrophy is a rare inherited metabolic disorder characterized by a typical phenotype. It may be associated with or without resistance to parathyroid hormone (pseudohypoparathyroidis...

    Seema Kapoor, Siddhartha Gogia, Ritu Paul… in The Indian Journal of Pediatrics (2006)

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