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Article
Open Access3D landscape of Hepatitis B virus interactions with human chromatins
Hepatitis B viral (HBV) DNAs, including covalently closed circular DNA (cccDNA) and integrated HBV DNA forms, are considered to be primary contributors to the development and progression of HBV-associated live...
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Article
Nitrogen addition to the canopy of Castanopsis chinensis (Sprengel) Hance promoted xylem formation in a subtropical forest in China
Nitrogen addition during 4 years to the canopy of Castanopsis chinensis (Sprengel) Hance promoted xylem formation, mainly by increasing radial growth during the early growth season. ...
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Article
Open AccessPCGF6 regulates stem cell pluripotency as a transcription activator via super-enhancer dependent chromatin interactions
Polycomb group (PcG) ring finger protein 6 (PCGF6), though known as a member of the transcription-repressing complexes, PcG, also has activation function in regulating pluripotency gene expression. However, th...
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Article
Open AccessWNT5B governs the phenotype of basal-like breast cancer by activating WNT signaling
Breast cancer is the leading cause of cancer-related death in women worldwide. Metastatic disease remains the primary cause of death in patients with breast cancer. Basal-like breast cancer (BLBC) is associate...
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Article
Open AccessDeep convolutional neural network for automatic discrimination between Fragaria × Ananassa flowers and other similar white wild flowers in fields
The images of different flower species had small inter-class variations across different classes as well as large intra-class variations within a class. Flower classification techniques are mainly based on the...
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Article
Heterologous signal peptides-directing secretion of Streptomyces mobaraensis transglutaminase by Bacillus subtilis
Microbial transglutaminase (MTG) from Streptomyces mobaraensis has been widely used for crosslinking proteins in order to acquire products with improved properties. To improve the yield and enable a facile and ef...
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Article
Open AccessCasein kinase 1α: biological mechanisms and theranostic potential
Casein kinase 1α (CK1α) is a multifunctional protein belonging to the CK1 protein family that is conserved in eukaryotes from yeast to humans. It regulates signaling pathways related to membrane trafficking, c...
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Article
Cell regeneration and cyclic catalysis of engineered Kluyveromyces marxianus of a d-psicose-3-epimerase gene from Agrobacterium tumefaciens for d-allulose production
d-Allulose as a low-energy and special bioactive monosaccharide sugar is essential for human health. In this study, the d-psicose-3-epimerase gene (DPEase) of Agrobacterium tumefaciens was transferred into thermo...
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Article
A new method studying the kinetics of l-lactic acid production by pellets Rhizopus oryzae in semi-continuous fermentation
l-Lactic acid production by Rhizopus oryzae in a semi-continuous fermentation system has been recognized as a promising technology. We studied l-lactic acid production in ten batches of s...
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Article
Zwitterionic hydrogels implanted in mice resist the foreign-body reaction
Zwitterionic hydrogels may be a useful biocompatible material, as they resist collagen capsule formation yet promote angiogenesis after implantation in mice.
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Article
Production of succinic acid and lactic acid by Corynebacterium crenatum under anaerobic conditions
A new succinic acid and lactic acid production bioprocess by Corynebacterium crenatum was investigated in mineral medium under anaerobic conditions. Corynebacterium crenatum cells with sustained acid production a...
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Article
A role for Ethylene-Insensitive 2 gene in the regulation of the ultraviolet-B response in Arabidopsis
The Arabidopsis Ethylene-Insensitive 2 (EIN2) gene was shown to be involved in the regulation of abiotic and biotic stresses, such as ozone stress, high salt, oxidative stress, lead and disease resistances. Howev...
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Article
Production of l-lactic acid by Rhizopus oryzae using semicontinuous fermentation in bioreactor
Semicontinuous fermentation using pellets of Rhizopus oryzae has been recognized as a promising technology for l-lactic acid production. In this work, semicontinuous fermentation of R. oryzae AS 3.819 for l-lacti...
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Article
Effects of fertilization on nutrient budget and nitrogen use efficiency of farmland soil under different precipitations in Northeastern China
Based on a consecutive 16-year field trial and meteorological data, the effects of fertilization on the nutrient budget and nitrogen use efficiency in farmland soil under different precipitation years were stu...
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Article
Cold treatment enhances lead resistance in Arabidopsis
As sessile organisms, plants usually experience several stresses simultaneously. It was shown that stress cross-tolerance may be induced by different stressors, including biotic factors as well as heavy metal,...
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Article
Cloning and Characterization of the DHDPS Gene Encoding the Lysine Biosynthetic Enzyme Dihydrodipocolinate Synthase from Zizania latifolia (Griseb)
Dihydrodipicolinate synthase (DHDPS) is the main enzyme of a specific branch of the aspartate pathway leading to lysine biosynthesis in higher plants. We have cloned and characterized the DHDPS gene from Zizania ...
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Article
Screening, breeding and metabolic modulating of a strain producing succinic acid with corn straw hydrolyte
Purpose In this paper, the high yield mutant strain was expected to be obtained for the industrial bioconversion of corn straw hydrolyte to succinic acid. Methods API biochemical reactions and 16S r RNA sequence ...
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Article
Evidence for a role of Ethylene-Insensitive 2 gene in the regulation of the oxidative stress response in Arabidopsis
The Arabidopsis Ethylene-Insensitive 2 (EIN2) gene has been shown to be involved in mediating the oxidative stress response; however, little is known about the underlying mechanisms involved. In this study, we fo...
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Article
The Role of GIGANTEA Gene in Mediating the Oxidative Stress Response and in Arabidopsis
The Arabidopsis GIGANTEA (GI) gene has been shown to be involved in the regulation of the oxidative stress response; however, little is known about the mechanism by which GI gene regulates the oxidative stress re...
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Article
Involvement of GIGANTEA gene in the regulation of the cold stress response in Arabidopsis
The Arabidopsis GIGANTEA (GI) gene has been shown to regulate several developmental processes, including photoperiod-mediated flowering, phytochrome B signaling, circadian clock, and carbohydrate metabolism. Howe...