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132 Result(s)
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Article
Open AccessStudy of serum visfatin and blood glucose and lipid metabolism, nafld in simple obese children
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Open AccessProfiles of responses of immunological factors to different subtypes of Kawasaki disease
The responses of immunological factors to different subtypes of Kawasaki disease (KD) remain poorly understood.
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Open Access2,3-Oxidosqualene cyclase protects liver cells from the injury of intermittent hypoxia by regulating lipid metabolism
2,3-Oxidosqualene cyclase (OSC), an important enzyme of cholesterol biosynthesis, catalyzes the highly selective cyclization of 2,3-monoepoxysqualene to lanosterol. Intermittent hypoxia (IH) is a hallmark feat...
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Open AccessFormula PSORI-CM01 eliminates psoriasis by inhibiting the expression of keratinocyte cyclin B2
Psoriasis is a chronically recurrent inflammatory skin disease, modern medicine could achieve good therapeutic effect, but these treatments led to recurrence of the psoriasis, more severe symptoms due to damag...
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Plasma PCSK9 level is unrelated to blood pressure and not associated independently with carotid intima–media thickness in hypertensives
Proprotein convertase subtilisin/kexin type 9 (PCSK9), a novel target for low-density lipoprotein cholesterol (LDL-C)-lowering therapy, has been found to possess multiple off-target effects in humans. The aim ...
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Open AccessVinegar amount in the process affected the components of vinegar-baked Radix Bupleuri and its hepatoprotective effect
Bupleuri Radix (in Chinese Chaihu), the dried roots of Bupleurum Chinense DC, is a traditional Chinese medicine widely used to treat fever, hepatitis, jaundice, nephritis, dizziness. When baked with vinegar, its ...
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Open AccessDioscin inhibits gastric tumor growth through regulating the expression level of lncRNA HOTAIR
As a member of non-coding RNAs family, long non-coding RNAs’ functions in cancer needs to be further investigated. It has been indicated that the functions of Hox transcript antisense intergenic RNA (lncRNA: H...
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Article
Gallstone disease is associated with arterial stiffness progression
Gallstones have been linked to dyslipidemia, metabolic syndrome and cardiovascular disease. Arterial stiffness is an indicator of subclinical atherosclerosis. The aim of this study was to prospectively examine...
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Open AccessEffects of phenolic constituents of daylily flowers on corticosterone- and glutamate-treated PC12 cells
Daylily flowers, the flower and bud parts of Hemerocallis citrina or H. fulva, are well known as Wang-You-Cao in Chinese, meaning forget-one’s sadness plant. However, the major types of active constituents respon...
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Open AccessCryptococcosis in patients with hematological diseases: a 14-year retrospective clinical analysis in a Chinese tertiary hospital
Cryptococcal infection has become a public health challenge globally. However, information about cryptococcal infection in patients with hematological diseases remains relatively rare.
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Open AccessHerbal compound 861 prevents hepatic fibrosis by inhibiting the TGF-β1/Smad/SnoN pathway in bile duct-ligated rats
This study was to evaluate the effects of herbal compound 861 (Cpd861) on ski-related novel protein N (SnoN) and transforming growth factor-β1 (TGF-β1) /Smad signaling in rats with bile duct ligation (BDL)-ind...
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Open AccessNetwork pharmacology-based strategy to investigate pharmacological mechanisms of Zuo**wan for treatment of gastritis
Zuo**wan (ZJW), a classic herbal formula, has been extensively used to treat gastric symptoms in clinical practice in China for centuries. However, the pharmacological mechanisms of ZJW still remain vague to ...
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Open AccessCompared efficacy of clopidogrel and ticagrelor in treating acute coronary syndrome: a meta-analysis
Ticagrelor has been acknowledged as a new oral antagonist of P2Y12-adenosine diphosphate receptor, as a strategy with more rapid onset as well as more significant platelet inhibition function in acute coronary...
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Open AccessHigh dose fluconazole in salvage therapy for HIV-uninfected cryptococcal meningitis
The 2010 Infectious Diseases Society of America (IDSA) guidelines for management of cryptococcal diseases recommend high dose fluconazole (≥ 800 mg/day), either alone or with other antifungal drugs, as alterna...
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Open AccessSystemic analysis of urinary stones from the Northern, Eastern, Central, Southern and Southwest China by a multi-center study
To provide some basis for the prevention of urinary stones in general population, we did a systemic analysis of urinary stones from Northern, Eastern, Central, Southern and Southwest China by a multi-center st...
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Open AccessMyocardial contrast echocardiography in the diagnosis of postoperative takotsubo myocardiopathy: case report and literature review
Takotsubo cardiomyopathy (TCM) is a brief ventricular dysfunction that usually occurs after emotional or physical stress. Here, we report a patient who underwent cardiac surgery and then developed TCM during t...
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Open AccessCervical squamous cell carcinoma-secreted exosomal miR-221-3p promotes lymphangiogenesis and lymphatic metastasis by targeting VASH1
Cancer-secreted exosomal miRNAs are emerging mediators of cancer-stromal cross-talk in the tumor environment. Our previous miRNAs array of cervical squamous cell carcinoma (CSCC) clinical specimens identified ...
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Open AccessOutcomes of general anesthesia versus conscious sedation for Stroke undergoing endovascular treatment: a meta-analysis
The impact of anesthesia strategy on the outcomes of acute ischemic stroke (AIS) patients undergoing endovascular treatment is currently controversy. Thus, we performed this meta-analysis to compare the differ...
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Open AccessInfected bone resection plus adjuvant antibiotic-impregnated calcium sulfate versus infected bone resection alone in the treatment of diabetic forefoot osteomyelitis
Managing with diabetic foot osteomyelitis (DFO) is challenging. Even after infective bone resection and thorough debridement, DFO is still difficult to cure and has a high recurrence rate. This retrospective s...
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Open AccessThe effect of quality of segmental bowel preparation on adenoma detection rate
The effectiveness in surveillance colonoscopy largely depends on the quality of bowel preparation. We aimed to investigate the quality of bowel preparation segmentally and its effect on Adenoma Detection Rate ...