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Article
Open AccessEfficacy and safety of oral ibrexafungerp in Chinese patients with vulvovaginal candidiasis: a phase III, randomized, double-blind study
To evaluate the efficacy and safety of oral ibrexafungerp (HS-10366) versus placebo in Chinese patients with vulvovaginal candidiasis (VVC).
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Article
Preparation, structure and magnetic properties of spherical FeSiB/Al2O3 soft magnetic composites prepared in a magnetic field
Amorphous FeSiB/Al2O3 soft magnetic composites were successfully fabricated in this work by applying an external magnetic field perpendicular or parallel to the magnetic toroidal surface, aiming to investigate th...
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Article
Open AccessBlow-Spun Si3N4-Incorporated Nanofibrous Dressing with Antibacterial, Anti-Inflammatory, and Angiogenic Activities for Chronic Wound Treatment
The effective and safe healing of chronic wounds, such as diabetic ulcers, presents a significant clinical challenge due to the adverse microenvironment in the wound that hinders essential processes of wound h...
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Article
Correlation Between Bariatric Surgery and the Risk of Multiple Myeloma: Results from an Evidence-Based Strategy
We conducted a meta-analysis of current literature to assess whether bariatric surgery(BS) has a positive effect on reducing the risk of multiple myeloma(MM).
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Article
Open AccessMaternal RNA transcription in Dlk1-Dio3 domain is critical for proper development of the mouse placental vasculature
The placenta is a unique organ for ensuring normal embryonic growth in the uterine. Here, we found that maternal RNA transcription in Dlk1-Dio3 imprinted domain is essential for placentation. PolyA signals were i...
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Open AccessAuthor Correction: A radiomics nomogram based on MSCT and clinical factors can stratify fibrosis in inflammatory bowel disease
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Article
Research trends and hotspots of sleep disorder and cancer: a bibliometric analysis via VOSviewer and CiteSpace
The purpose of this research is to further understand the research status and summarize the research hotspots of sleep disorder and cancer, so as to provide insights into future researches.
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Article
Open AccessPhase I pharmacokinetic, safety, and preliminary efficacy study of tiragolumab in combination with atezolizumab in Chinese patients with advanced solid tumors
Tiragolumab is an immunoglobulin G1 monoclonal antibody targeting the immune checkpoint T cell immunoreceptor with immunoglobulin and immunoreceptor ITIM domains. Targeting multiple immune pathways may improve...
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Article
Open AccessEvaluating precipitation prediction skill for the pre- and postrainy seasons in South China in ECMWF subseasonal forecasts
The rainy season in South China is divided into two phases, the pre- and postrainy seasons, according to the seasonal progression of the East Asian summer monsoon. The precipitation prediction skills for the t...
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Article
Treatment of Meniere’s disease with simultaneous triple semicircular canal occlusion and cochlear implantation
Report three cases of simultaneous triple semicircular canal occlusion (TSCO) and cochlear implantation (CI) as the treatment of intractable Meniere’s disease (MD).
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Article
Generalized Dissipativity of Fuzzy Systems by Memory Sampled-Data Control
This paper addresses the generalized dissipative problem for fuzzy systems with memory sampled-data control. The aim is to devise the memory sampled-data controller such that the considered system is generaliz...
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Article
ZnO-incorporated chitin hydrogels for infected wound therapy
Chronic wounds caused by pathogenic bacterial infections have been a worldwide medical threat and challenge, ZnO is a promising antibacterial agent to promote infected wound healing. However, ZnO particles nee...
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Article
MeV astrophysical spectroscopic surveyor (MASS): a compton telescope mission concept
We propose a future mission concept, the MeV Astrophysical Spectroscopic Surveyor (MASS), which is a large area Compton telescope using 3D position sensitive cadmium zinc telluride (CZT) detectors optimized fo...
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Article
Open AccessHigh-resolution Annual Dynamic dataset of Curve Number from 2008 to 2021 over Conterminous United States
The spatial distribution and data quality of curve number (CN) values determine the performance of hydrological estimations. However, existing CN datasets are constrained by universal-applicability hypothesis,...
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Article
Open AccessClinical and electroencephalogram characteristics of methylmalonic acidemia with MMACHC and MUT gene mutations
This study investigated the clinical, imaging, and electroencephalogram (EEG) characteristics of methylmalonic acidemia (MMA) with nervous system damage as the primary manifestation.
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Article
Open AccessRetraction Note: Caveolin-1 promotes invasion and metastasis by upregulating Pofut1 expression in mouse hepatocellular carcinoma
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Article
Open AccessPick-up single-cell proteomic analysis for quantifying up to 3000 proteins in a Mammalian cell
The shotgun proteomic analysis is currently the most promising single-cell protein sequencing technology, however its identification level of ~1000 proteins per cell is still insufficient for practical applica...
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Article
Repaglinide restrains HCC development and progression by targeting FOXO3/lumican/p53 axis
The recent focus on the roles of N-linked glycoproteins in carcinogenesis across various malignancies has prompted our exploration of aberrantly expressed glycoproteins responsible for HCC progression and pote...
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Article
Measurement and Analysis of Impulse Source Produced by Ballistic Shock Wave Therapy Device in Different Medium Using PVDF Sensor
Radial extracorporeal shock wave therapy (rESWT) has been used in clinical and rehabilitation fields. However, the formulation of related clinical treatment protocols and the full potential of its therapeutic ...
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Article
Baricitinib relieves DSS-induced ulcerative colitis in mice by suppressing the NF-κB and JAK2/STAT3 signalling pathways
Ulcerative colitis (UC) is a relapsing inflammatory disease with a unique aetiology. The treatment of UC is challenging, and the current clinical therapeutics for colitis have limited efficacy. Thus, finding n...
