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Article
Famine exposure in early life is associated with visceral adipose dysfunction in adult females
Epidemiologic studies have revealed that early life malnutrition increases later risk of metabolic diseases. The visceral adiposity index (VAI) is a novel sex-specific index that shows promise as a marker of v...
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Article
Open AccessExposure to famine in early life and chronic kidney diseases in adulthood
Chronic kidney disease (CKD) is an increasing contributor to the global disease burden. Previous findings indicated that exposure to famine in early life was associated with various metabolic diseases and urin...
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Article
Open AccessAge and gender-specific distribution of metabolic syndrome components in East China: role of hypertriglyceridemia in the SPECT-China study
Chinese population are experiencing remarkably changes of economic and cultural environments. The present study was to examine the prevalence of metabolic syndrome (MetS) by age between genders and to investig...
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Article
Open AccessNeck circumference as an independent indicator of visceral obesity in a Chinese population
Neck circumference (NC) was reported to be associated with visceral obesity in some specific subjects. However, no studies have reported whether NC could identify visceral obesity in the general population. He...
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Article
Open AccessThe Triglycerides and Glucose Index rather than HOMA-IR is more associated with Hypogonadism in Chinese men
Previous studies have reported that insulin resistant and low testosterone are related. The triglyceride and glucose index (TyG) well mirrors insulin sensitivity. No study investigated the application of TyG i...
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Article
Open AccessVisceral adiposity and renal function: an observational study from SPECT-China
Lipid accumulation product (LAP) is a novel and effective index of visceral adiposity distribution based on waist circumference and triglycerides concentration. Few studies investigated the relationship betwee...
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Article
Open AccessSerum alanine aminotransferase/aspartate aminotransferase ratio is one of the best markers of insulin resistance in the Chinese population
The alanine aminotransferase (ALT)/aspartate aminotransferase (AST) ratio is reportedly associated with insulin resistance (IR). However, few studies have explored the relationship between the ALT/AST ratio an...
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Article
Association of lead exposure with cardiovascular risk factors and diseases in Chinese adults
We aimed to determine whether lead exposure was associated with cardiovascular diseases (CVD) and risk factors in Chinese adults. Five thousand three hundred and forty-eight subjects were enrolled from 16 site...
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Article
Open AccessBlood lead level is associated with non-alcoholic fatty liver disease in the Yangtze River Delta region of China in the context of rapid urbanization
China has undergone rapid urbanization in the past three decades. We aimed to report blood lead level (B-Pb) in the most rapidly urbanized Yangtze River Delta Region of China, and explore the association B-Pb ...
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Article
Open AccessHealth-related quality of life in type-2 diabetes patients: a cross-sectional study in East China
Used the EuroQoL-5 dimension (EQ-5D) to evaluate the health status of 5310 residents who live in East China, and compared the health-related quality of life (HRQoL) with 311 patients with type 2 diabetes as we...
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Article
Follicle stimulating hormone, its novel association with sex hormone binding globulin in men and postmenopausal women
Follicle stimulating hormone plays direct roles in a variety of nongonadal tissues and sex hormone binding globulin is becoming the convergence of the crosstalk among metabolic diseases. However, no studies ha...
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Article
Open AccessSerum Uric Acid Is Associated with Erectile Dysfunction: A Population-Based Cross-Sectional Study in Chinese Men
The role that serum uric acid (UA) plays in the pathophysiological development of erectile dysfunction (ED) is controversial. We aimed to screen the factors related with ED, and to examine the association betw...
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Article
Open AccessCadmium exposure and its association with serum uric acid and hyperuricemia
Few studies have investigated the association between serum uric acid (UA) and cadmium exposure. Our previous study revealed a significantly higher blood cadmium (CdB) level in the Chinese population compared ...
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Article
Open AccessBerberine improves glucogenesis and lipid metabolism in nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) is considered a critical hepatic manifestation of metabolic syndrome. Berberine (BBR) exerts anti-hyperglycemic and anti-dyslipidemic effects and can also ameliorate NA...
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Article
Exposure to severe famine in the prenatal or postnatal period and the development of diabetes in adulthood: an observational study
Limited studies have compared the effect of prenatal or postnatal exposure to different severities of famine on the risk of develo** diabetes. We aimed to measure the association between diabetes in adulthoo...
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Article
Open AccessAssociations of blood lead levels with reproductive hormone levels in men and postmenopausal women: Results from the SPECT-China Study
We examined whether blood lead levels (BLLs) were associated with reproductive hormone levels in a cross-sectional study using data from the SPECT-China study. We selected 2286 men and 1571 postmenopausal wome...
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Article
Blood cadmium in Chinese adults and its relationships with diabetes and obesity
The aim of this study is to evaluate blood cadmium levels (BCLs) in Chinese adults and explore whether blood cadmium is associated with diabetes or obesity. This study included 5544 adults from a cross-section...
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Article
Open AccessThe nine-year changes of the incidence and characteristics of metabolic syndrome in China: longitudinal comparisons of the two cross-sectional surveys in a newly formed urban community
To assess the 9-year changes of the incidence and characteristics of metabolic syndrome (MetS) in Chinese community under the background of dramatically changed environment.
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Article
Blood Cadmium Level Associates with Lower Testosterone and Sex Hormone-Binding Globulin in Chinese men: from SPECT-China Study, 2014
Cadmium is a widespread environmental pollutant. We aimed to determine whether blood cadmium level (BCL) associates with reproductive hormones in a cross-sectional study. Our data were from SPECT-China. We sel...
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Article
Open AccessFollicle-stimulating hormone associates with prediabetes and diabetes in postmenopausal women
No study explores the association between follicle-stimulating hormone (FSH) and glucose metabolism in general women. We aim to investigate whether the variation of FSH is associated with prediabetes and diabe...
