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1,147 Result(s)
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Article
Process parameters optimization of differential heating push-bending for small bending radius tube based on orthogonal experiments
A process of differential heating push-bending (DHP-B) was proposed to enhance the forming quality of thin-walled tubes with small bending radius. Finite element numerical simulation and the orthogonal test me...
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Article
On Some Results of Mues, Bergweiler and Eremenko Concerning Differential Polynomials
In this paper, we shall prove the following result: Let f be a transcendental meromorphic function, and let P(z) be a polynomial with \(\deg P\ge 2\) ...
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Article
Open AccessGasdermin E benefits CD8+T cell mediated anti-immunity through mitochondrial damage to activate cGAS-STING-interferonβ axis in colorectal cancer
Pyroptosis belongs to a unique type of programmed cell death among which GSDME is reported to exert anti-tumor immunity. However, the underlying mechanisms of how to boost tumor-infiltrating lymphocytes and wh...
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Photothermal therapy of tuberculosis using targeting pre-activated macrophage membrane-coated nanoparticles
Conventional antibiotics used for treating tuberculosis (TB) suffer from drug resistance and multiple complications. Here we propose a lesion–pathogen dual-targeting strategy for the management of TB by coating M...
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Evolution of the Recharge and Discharge of Groundwater in Plain Area of the Hami Basin from 1959 to 2021
Groundwater serves crucial roles in resource preservation, ecological maintenance, and geological security in addition to being a significant component of water supplies. This work meticulously summarized data...
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Mammalian IRE1α dynamically and functionally coalesces with stress granules
Upon endoplasmic reticulum (ER) stress, activation of the ER-resident transmembrane protein kinase/endoribonuclease inositol-requiring enzyme 1 (IRE1) initiates a key branch of the unfolded protein response (U...
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Article
Evaluating the exceedance probability of the runout distance of rainfall-induced landslides using a two-stage FEM-MPM approach
Evaluating the exceedance probability within a time period (EPT) of the runout distance of rainfall-induced landslides is important for the quantitative risk assessment (QRA) of rainfall-induced landslides. Ho...
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Open AccessSurgical intervention of Lemierre’s syndrome: a case report and review of the literature
Lemierre’s syndrome is a fatal and rare disease that is typically characterized by oropharyngeal infection and internal jugular vein thrombosis. Timely institution of appropriate antibiotics is the standard tr...
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Genome-wide identification of thaumatin-like protein family in pear and functional analysis their roles in pollen growth
Thaumatin-like proteins (TLPs) are crucial for plant growth and development. However, the function of TLPs in pear pollen tube growth has not been fully elucidated. In this study, we characterized 40 PbrTLPs with...
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Article
Open AccessMiR-653-5p drives osteoarthritis pathogenesis by modulating chondrocyte senescence
Due to the unclear pathogenesis of osteoarthritis (OA), effective treatment for this ailment is presently unavailable. Accumulating evidence points to chondrocyte senescence as a key driver in OA development. ...
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Article
Image defogging method combining variational model and alternating least squares
Traditional image dehazing methods based on physical model do not consider the coupling of different color channels, which will produce artifacts during dehazing. To solve this problem, an improved image fog r...
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Open AccessProtosappanin B enhances the chemosensitivity of 5-fluorouracil in colon adenocarcinoma by regulating the LINC00612/microRNA-590-3p/Golgi phosphoprotein 3 axis
5-fluorouracil (5-FU) is conventionally used in chemotherapy for colon adenocarcinomas. Acquired resistance of 5-FU remains a clinical challenge in colon cancer, and efforts to develop targeted agents to reduc...
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Effects of Platelet-Rich Plasma Combined with Physical Therapy on IL-1β, TGF-β1, and MMP-3 in Patients with Knee Osteoarthritis
The occurrence of osteoarthritis in the knee joint is regulated by a complex network, and there is currently no specific therapeutic drug available. Functional exercises and treatments targeting inflammatory f...
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Silencing DDX3 Attenuates Interleukin-1β-Induced Intervertebral Disc Degeneration Through Inhibiting Pyroptosis
Intervertebral disc degeneration (IVDD) is a common disorder associated with chronic inflammation and cell death. In this study, an IVDD rat model was created through Interleukin-1β (IL-1β) injection. The dege...
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Article
Comprehensive analysis of stress-activated protein kinase genes (OsSAPKs) in rice flowering time
The rice SnRK2 members SAPK4, SAPK5, SAPK7 and SAPK10 are positive regulators involved in the regulation of rice flowering, while other single mutants exhibited no effect on rice flowering.
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Article
A novel functional allele of Ehd3 controls flowering time in rice
Rice flowering time determines its geographical distribution and yield traits. As a short-day plant, rice can grow in the northern long-day conditions due to the functional mutations of many photosensitive gen...
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Open AccessCorrection: Kinome and phosphoproteome reprogramming underlies the aberrant immune responses in critically ill COVID-19 patients
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Article
An Anisotropic Failure Criterion for Jointed Rocks Under Triaxial Stress Conditions
In the field of rock engineering, the anisotropic failure criterion plays a vital role in predicting the strength of rocks with varying degrees of anisotropy. This study presents jointed rock as a composite ma...
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DENS-YOLOv6: a small object detection model for garbage detection on water surface
The study of garbage detection on water surface is of great significance for the development of water surface garbage monitoring and automated water surface garbage salvage. However, in water surface garbage s...
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Towards automatically generating meal plan based on genetic algorithm
With the rising of the concept of balanced diet, more and more people pay attention to the healthy meal plans. However, a meal plan is usually difficult to meet people’s taste preferences and health standards ...