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Article
Open AccessKinetics of angiogenic changes in a new mouse model for hepatocellular carcinoma
The increasing incidence of hepatocellular carcinoma in Western countries has led to an expanding interest of scientific research in this field. Therefore, a vast need of experimental models that mimic the nat...
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Article
Open AccessA taxonomy of epithelial human cancer and their metastases
Microarray technology has allowed to molecularly characterize many different cancer sites. This technology has the potential to individualize therapy and to discover new drug targets. However, due to technolog...
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Article
Molecular and clinico-pathological markers in rectal cancer: a tissue micro-array study
The aims of the study were to study the effect of pre-operative treatment on the expression of tumour-related proteins and to correlate the expression of these proteins with response and survival of patients w...
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Article
A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells
The variability in the prognosis of individuals with hepatocellular carcinoma (HCC) suggests that HCC may comprise several distinct biological phenotypes. These phenotypes may result from activation of differe...
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Article
Expression of neural cell adhesion molecule in human liver development and in congenital and acquired liver diseases
In the liver, neural cell adhesion molecule (NCAM) is a marker of immature cells committed to the biliary lineage and is expressed by reactive bile ductules in human liver diseases. We investigated the possib...