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  1. Article

    Open Access

    Nono deficiency impedes the proliferation and adhesion of H9c2 cardiomyocytes through Pi3k/Akt signaling pathway

    Congenital heart disease (CHD) is the most common type of birth defect and the main noninfectious cause of death during the neonatal stage. The non-POU domain containing, octamer-binding gene, NONO, performs a va...

    Yu-Qing Lei, Zhou-Jie Ye, Ya-Lan Wei, Li-** Zhu, Xu-Dong Zhuang in Scientific Reports (2023)

  2. Article

    Open Access

    Pan-cancer single-cell analysis reveals the heterogeneity and plasticity of cancer-associated fibroblasts in the tumor microenvironment

    Cancer-associated fibroblasts (CAFs) are the predominant components of the tumor microenvironment (TME) and influence cancer hallmarks, but without systematic investigation on their ubiquitous characteristics ...

    Han Luo, Xuyang **a, Li-Bin Huang, Hyunsu An, Minyuan Cao in Nature Communications (2022)

  3. Article

    Open Access

    Missed Monteggia fractures in children treated by open reduction of the radial head and corrective osteotomy of the ulna

    Missed Monteggia fractures in children may cause pain, deformity, decreased range of motion, neurological symptoms, and late arthritis of the elbow. Numerous surgical techniques have been advocated to reconstr...

    Shu Cao, Zhong-Gen Dong, Li-Hong Liu, Jian-Wei Wei, Zhao-Biao Luo in Scientific Reports (2022)

  4. Article

    Open Access

    Superstretchable, yet stiff, fatigue-resistant ligament-like elastomers

    Ligaments are flexible and stiff tissues around joints to support body movements, showing superior toughness and fatigue-resistance. Such a combination of mechanical properties is rarely seen in synthetic elas...

    Mengxue Li, Lili Chen, Yiran Li, **aobin Dai, Zhekai ** in Nature Communications (2022)

  5. Article

    Open Access

    Effectiveness of Lymphatic Contrast Enhanced Ultrasound in the diagnosis of Cervical Lymph node metastasis from papillary thyroid carcinoma

    Cervical lymph node metastasis (CLNM) is common in patients with papillary thyroid carcinoma (PTC), which is responsible for tumor staging and surgical strategy. The accurate preoperative identification of CLN...

    Ying Wei, Yun Niu, Zhen-long Zhao, **ao-**g Cao, Li-li Peng, Yan Li in Scientific Reports (2022)

  6. Article

    Open Access

    Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk

    Dysregulated extravillous trophoblast invasion and proliferation are known to increase the risk of recurrent spontaneous abortion (RSA); however, the underlying mechanism remains unclear. Herein, in our retros...

    **ao-Hui Wang, Sha Xu, **ang-Yu Zhou, Rui Zhao, Yan Lin, **g Cao in Nature Communications (2021)

  7. Article

    Open Access

    Visible-light photoredox-catalyzed umpolung carboxylation of carbonyl compounds with CO2

    Photoredox-mediated umpolung strategy provides an alternative pattern for functionalization of carbonyl compounds. However, general approaches towards carboxylation of carbonyl compounds with CO2 remain scarce. H...

    Guang-Mei Cao, **n-Long Hu, Li-Li Liao, Si-Shun Yan, Lei Song in Nature Communications (2021)

  8. Article

    Open Access

    Competing risk model to determine the prognostic factors and treatment strategies for elderly patients with glioblastoma

    The prognostic factors and optimal treatment for the elderly patient with glioblastoma (GBM) were poorly understood. This study extracted 4975 elderly patients (≥ 65 years old) with histologically confirmed GB...

    Zhuo-yi Liu, Song-shan Feng, Yi-hao Zhang, Li-yang Zhang in Scientific Reports (2021)

  9. Article

    Open Access

    An immune checkpoint score system for prognostic evaluation and adjuvant chemotherapy selection in gastric cancer

    Immunosuppressive molecules are extremely valuable prognostic biomarkers across different cancer types. However, the diversity of different immunosuppressive molecules makes it very difficult to accurately pre...

    Jia-Bin Wang, ** Li, **ao-Long Liu, Qiao-Ling Zheng, Yu-Bin Ma in Nature Communications (2020)

  10. Article

    Open Access

    Reductive dearomative arylcarboxylation of indoles with CO2 via visible-light photoredox catalysis

    Catalytic reductive coupling of two electrophiles and one unsaturated bond represents an economic and efficient way to construct complex skeletons, which is dominated by transition-metal catalysis via two elec...

    Wen-Jun Zhou, Zhe-Hao Wang, Li-Li Liao, Yuan-Xu Jiang, Ke-Gong Cao in Nature Communications (2020)

  11. No Access

    Article

    Atomic imaging of the edge structure and growth of a two-dimensional hexagonal ice

    The formation and growth of water-ice layers on surfaces and of low-dimensional ice under confinement are frequent occurrences14. This is exemplified by the extensive reporting of two-dimensional (2D) ice on met...

    Runze Ma, Duanyun Cao, Chongqin Zhu, Ye Tian, **bo Peng, **g Guo, Ji Chen in Nature (2020)

  12. Article

    Open Access

    Tissue-specific microRNA expression alters cancer susceptibility conferred by a TP53 noncoding variant

    A noncoding polymorphism (rs78378222) in TP53, carried by scores of millions of people, was previously associated with moderate risk of brain tumors and other neoplasms. We find a positive association between thi...

    Qipan Deng, Hui Hu, **nfang Yu, Shuanglin Liu, Lei Wang in Nature Communications (2019)

  13. Article

    Open Access

    DNA methylation of antisense noncoding RNA in the INK locus (ANRIL) is associated with coronary artery disease in a Chinese population

    To explore the association between methylation of antisense non-coding RNA in the INK4 locus (ANRIL) and coronary artery disease (CAD) development. Methylation levels of ANRIL in 100 subjects with CAD and 100 ...

    Chen-Hui Zhao, Hai-Tao Cao, **g Zhang, Qiao-Wei Jia, Feng-Hui An in Scientific Reports (2019)

  14. Article

    Open Access

    Latent Infection of Valsa mali in the Seeds, Seedlings and Twigs of Crabapple and Apple Trees is a Potential Inoculum Source of Valsa Canker

    A real-time quantitative PCR assay using a species-specific primer pair was developed to rapidly and accurately quantify Valsa mali, the causative pathogen of apple Valsa canker (AVC), in crabapple seeds, crabapp...

    **ang-long Meng, **ng-hua Qi, Ze-yuan Han, Yong-bin Guo, Ya-nan Wang in Scientific Reports (2019)

  15. Article

    Open Access

    GmSYP24, a putative syntaxin gene, confers osmotic/drought, salt stress tolerances and ABA signal pathway

    As major environment factors, drought or high salinity affect crop growth, development and yield. Transgenic approach is an effective way to improve abiotic stress tolerance of crops. In this study, we compara...

    Li-Miao Chen, Yi-Sheng Fang, Chan-Juan Zhang, Qing-Nan Hao, Dong Cao in Scientific Reports (2019)

  16. Article

    Open Access

    The genetic Creutzfeldt-Jakob disease with E200K mutation: analysis of clinical, genetic and laboratory features of 30 Chinese patients

    Genetic Creutzfeldt-Jakob disease (gCJD) with E200K mutation is one of the common subtypes of human genetic prion diseases worldwide. In this study, we systematically analyzed 30 Chinese E200K gCJD cases for t...

    Li-** Gao, Qi Shi, Kang **ao, **g Wang, Wei Zhou, Cao Chen in Scientific Reports (2019)

  17. Article

    Publisher Correction: The effect of hydration number on the interfacial transport of sodium ions

    In this Letter, the links to Supplementary Videos 5, 7, 9 and 10 were incorrect, and there were some formatting errors in the Supplementary Video legends. These errors have been corrected online.

    **bo Peng, Duanyun Cao, Zhili He, **g Guo, Prokop Hapala, Runze Ma, Bowei Cheng in Nature (2018)

  18. Article

    Open Access

    Hub-organized parallel circuits of central circadian pacemaker neurons for visual photoentrainment in Drosophila

    Circadian rhythms are orchestrated by a master clock that emerges from a network of circadian pacemaker neurons. The master clock is synchronized to external light/dark cycles through photoentrainment, but the...

    Meng-Tong Li, Li-Hui Cao, Na **ao, Min Tang, Bowen Deng, Tian Yang in Nature Communications (2018)

  19. Article

    Open Access

    Evolution of thiolate-stabilized Ag nanoclusters from Ag-thiolate cluster intermediates

    The synthesis of atomically precise thiolate-stabilized silver (Ag) nanoclusters is the subject of intense research interest, yet the formation mechanism of such nanoclusters remains obscure. Here, electrospra...

    Yitao Cao, Jiahao Guo, Run Shi, Geoffrey I. N. Waterhouse in Nature Communications (2018)

  20. No Access

    Article

    The effect of hydration number on the interfacial transport of sodium ions

    Ion hydration and transport at interfaces are relevant to a wide range of applied fields and natural processes15. Interfacial effects are particularly profound in confined geometries such as nanometre-sized chan...

    **bo Peng, Duanyun Cao, Zhili He, **g Guo, Prokop Hapala, Runze Ma, Bowei Cheng in Nature (2018)

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