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Open AccessFourth NF-κB site in HIV-1 subtype-C LTR confers functional advantage to viral gene expression
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Open AccessThe importance of individualized article-specific metrics for evaluating research productivity
This editorial discusses the rationale for using article-specific rather than journal-specific metrics for evaluating highly published authors.
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Open AccessMicroRNA profile changes in human immunodeficiency virus type 1 (HIV-1) seropositive individuals
MicroRNAs (miRNAs) play diverse roles in regulating cellular and developmental functions. We have profiled the miRNA expression in peripheral blood mononuclear cells from 36 HIV-1 seropositive individuals and ...
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Open AccessThe 2008 Retrovirology Prize: Ben Berkhout and his RNA world
Ben Berkhout wins the 2008 Retrovirology Prize.
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Open AccessH-index, mentoring-index, highly-cited and highly-accessed: how to evaluate scientists?
How best to evaluate scientists within a peer group is a difficult task. This editorial discusses the use of the H-index and total citations. It also raises the consideration of a mentoring-index and the value...
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Open AccessRecognizing mid-career productivity: the 2008 RetrovirologyPrize, call for nomination
A recent analysis suggested a narrow age range for productivity of innovative work by researchers. The Retrovirology Prize seeks to recognize the research of a mid-career retrovirologist between the ages of 45 an...
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Open AccessRemembering Ralph Grassmann (1957 – 2008)
Friends and colleagues of Ralph Grassmann write their remembrances.
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Open AccessPlease comment, but with civility
Retrovirology provides the opportunity for readers to post comments online for all published articles. These comments are moderated by the journal editors and are often peer reviewed prior to posting. Retrovirolo...
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Open AccessActivation of HIV-1 expression and replication by cGMP dependent protein kinase type 1-β (PKG1β)
The effect of cGMP (cyclic GMP) dependent protein kinase 1-β (PKG1-β) and cGMP analogues on transcriptional activity and replication of human immunodeficiency virus type 1 (HIV-1) was investigated. Transfectio...
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Open AccessWorld AIDS Day 2007: AIDS at 26, are we there yet?
This editorial comments on selected progress made in combating the acquired immune deficiency syndrome (AIDS) after 26 years and some of the remaining challenges.
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Open AccessSmall non-coding RNAs, mammalian cells, and viruses: regulatory interactions?
Recent findings suggest that mammalian cells can use small non-coding RNAs (ncRNA) to regulate physiological viral infections. Here, we comment on several lines of evidence that support this concept. We discus...
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Open AccessThe young, not-so-young, and the 2007 RetrovirologyPrize: call for nominations
Recent findings suggest an aging scientific work force and an almost static publishing productivity in the United States. The Retrovirology Prize seeks to recognize and encourage the work of a mid-career retrovir...
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Open AccessImpact factor, H index, peer comparisons, and Retrovirology: is it time to individualize citation metrics?
There is a natural tendency to judge a gift by the attractiveness of its wrap**. In some respect, this reflects current mores of measuring the gravitas of a scientific paper based on the journal cover in whi...
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Open AccessMethylation: a regulator of HIV-1 replication?
Recent characterizations of methyl transferases as regulators of cellular processes have spurred investigations into how methylation events might influence the HIV-1 life cycle. Emerging evidence suggests that...
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Open AccessLibya, HIV, and open communication
This year-end editorial discusses several points including the recent Libyan verdict sentencing five Bulgarian nurses and a Palestinian doctor to death for allegedly infecting 426 children with HIV. It also co...
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Open AccessHIV-1 Tat interaction with Dicer: requirement for RNA
Dicer is an RNase III which processes two classes of cellular small RNAs: the microRNAs (miRNA) and short interfering RNAs (siRNA). Previously, we observed that over-expressed HIV-1 Tat protein can suppress th...
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Open AccessRetrovirology: 3 at age 2
Retrovirology announces new editorial board members and reprises progress over the first two years of publishing.
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Open AccessThe 2006 RetrovirologyPrize: call for nominations
Retrovirology announces a nomination call for its 2006 prize to recognize an outstanding mid-career retrovirologist. The 2005 Retrovirology prize was awarded to Dr. Stephen P. Goff.
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Open AccessA peptide-loaded dendritic cell based cytotoxic T-lymphocyte (CTL) vaccination strategy using peptides that span SIV Tat, Rev, and Env overlap** reading frames
CTL based vaccine strategies in the macaque model of AIDS have shown promise in slowing the progression to disease. However, rapid CTL escape viruses can emerge rendering such vaccination useless. We hypothesi...
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Open AccessChanges in microRNA expression profiles in HIV-1-transfected human cells
MicroRNAs (miRNAs) are small RNAs of 18–25 nucleotides (nt) in length that play important roles in regulating a variety of biological processes. Recent studies suggest that cellular miRNAs may serve to control...