31,006 Result(s)

Article

LncRNA ZFAS1 regulates ATIC transcription and promotes the proliferation and migration of hepatocellular carcinoma through the PI3K/AKT signaling pathway

Long noncoding RNAs (lncRNAs) exert a significant influence on various cancer-related processes through their intricate interactions with RNAs. Among these, lncRNA ZFAS1 has been implicated in oncogenic roles ...

Baoyang Luo, Lin Zhuang, Ju Huang… in Journal of Cancer Research and Clinical On… (2024)

Article

Correction: Discrepancies in perceived family resilience between adolescents with chronic illness and parents: using response surface analysis to examine the relationship with adolescents’ psychological adjustment

Meijia Chen, Liya Ren, Hao Jiang, Yuxin Wang, Li** Zhang, Chaoqun Dong in BMC Psychiatry (2024)

Article

Metagenomic next-generation sequencing promotes diagnosis and treatment of Pneumocystis jirovecii pneumonia in non-HIV infected children: a retrospective study

Metagenomic next-generation sequencing (mNGS) excels in diagnosis of infection pathogens. We aimed to evaluate the performance of mNGS for the diagnosis of Pneumocystis jirovecii pneumonia (PJP) in non-HIV infect...

Zhenyu Zhang, Tingyan Liu, Meixiu Ming, Meili Shen, Yi Zhang… in BMC Pulmonary Medicine (2024)

Article

Safety of embryo cryopreservation: insights from mid-term placental transcriptional changes

In recent years, with benefits from the continuous improvement of clinical technology and the advantage of fertility preservation, the application of embryo cryopreservation has been growing rapidly worldwide....

Qin-Yu Luo, Si-Wei Zhang, Hai-Yan Wu, Jia-Ying Mo… in Reproductive Biology and Endocrinology (2024)

Article

What determines informal care need among community-dwelling older adults in China? Results from a longitudinal study

With an intensified aging population and an associated upsurge of informal care need in China, there is an ongoing discussion around what factors influence this need among older adults. Most existing studies a...

Liangwen Zhang, Shuyuan Shen, Wenzheng Zhang, Ya Fang in BMC Geriatrics (2024)

Article

The value of deep learning-based X-ray techniques in detecting and classifying K-L grades of knee osteoarthritis: a systematic review and meta-analysis

Knee osteoarthritis (KOA), a prevalent degenerative joint disease, is primarily diagnosed through X-ray imaging. The Kellgren-Lawrence grading system (K-L) is the gold standard for evaluating KOA severity thro...

Haoming Zhao, Liang Ou, Ziming Zhang, Le Zhang, Ke Liu, Jianjun Kuang in European Radiology (2024)

Article

Bow hunter’s syndrome due to an anomalous right vertebral artery origin and contralateral absence: a case report and literature review

Bow Hunter’s syndrome (BHS), also known as rotational vertebral artery occlusion (RVAO), is a rare condition characterized by dynamic vertebrobasilar insufficiency due to position-dependent occlusion of the ve...

Li Zhang, Yu Gao, **ao Yu, Ying Guo, Zhe Piao, Guangxian Nan in BMC Neurology (2024)

Article

Does metformin really reduce prostate cancer risk: an up-to-date comprehensive genome-wide analysis

The relationship between metformin use and prostate cancer (PCa) risk has yet to be clear despite more than a decade of debate on this topic. Hence, we aimed to investigate the causal role of metformin in redu...

**nxing Zhang, Zhen Li in Diabetology & Metabolic Syndrome (2024)

Article

Decreased levels of PTCSC3 promote the deterioration of prostate cancer and affect the prognostic outcome of patients through sponge miR-182-5p

Prostate cancer, characterized by its insidious onset and short overall survival, and has seen a rise in incidence over recent decades. This study aims to investigate the expression and molecular mechanism of ...

Lin Cheng, Shuhui Li, Deqi Jiang, Rongkai Sun, Yueshan Wang, Jianchao Zhang… in BMC Urology (2024)

Article

An analysis of the role of GAB2 in pan-cancer from a multidimensional perspective

To explore the role of GAB2 in pan-cancer based on bioinformatics analysis.

Yi Yin, Yong Li, Yaoyang Zhang, Qiucheng Jia, Huiming Tang… in Discover Oncology (2024)

Article

Good outcome with conservative treatment of delayed spinal epidural hematoma following combined spinal-epidural anesthesia: a rare case report

Delayed spinal epidural hematoma (SEH) following central neuraxial block (CNB) is a rare but serious complication. The underlying causes of SEH associated with neuraxial anesthesia are still unclear. Furthermo...

Hui Yao, Xuejie Li, Shize Leng, Hui Zhang in BMC Anesthesiology (2024)

Article

The effect of large channel-based foraminoplasty on lumbar biomechanics in percutaneous endoscopic discectomy: a finite element analysis

This study aimed to evaluate the effect of foraminoplasty using large-channel endoscopy during TESSYS on the biomechanics of the lumbar spine.

Wei Sun, Duohua Li, Sicong Zhao, Hao Fu… in Journal of Orthopaedic Surgery and Research (2024)

Article

Simultaneous bilateral video-assisted thoracic surgery is safe and feasible for multiple primary lung cancers

The treatment for bilateral synchronous multiple primary lung cancers (MPLC) remains challenging. Simultaneous bilateral video-assisted thoracic surgery (VATS) may be an optimal treatment with curative intent,...

Libing Yang, Chao Guo, Ye Zhang, Huizhen Jiang… in Journal of Cardiothoracic Surgery (2024)

Article

Pharmacological activity and clinical application analysis of traditional Chinese medicine ginger from the perspective of one source and multiple substances

All types of ginger have common fundamental components, although they possess distinct strengths and inclinations when it comes to effectiveness and medicinal applications. Fresh ginger possesses the ability t...

Cheng Zhang, Anyang Rao, Cui Chen, Yuqing Li, **uchi Tan, Jiaxin Long… in Chinese Medicine (2024)

Article

The clinical value of artificial intelligence in assisting junior radiologists in thyroid ultrasound: a multicenter prospective study from real clinical practice

This study is to propose a clinically applicable 2-echelon (2e) diagnostic criteria for the analysis of thyroid nodules such that low-risk nodules are screened off while only suspicious or indeterminate ones a...

Dong Xu, Lin Sui, Chunquan Zhang, **g **ong, Vicky Yang Wang, Yahan Zhou… in BMC Medicine (2024)

Article

Association between neural prosody discrimination and language abilities in toddlers: a functional near-infrared spectroscopy study

Language delay affects near- and long-term social communication and learning in toddlers, and, an increasing number of experts pay attention to it. The development of prosody discrimination is one of the earli...

YanRu Guo, YanWei Li, FuLin Liu, Huan** Lin, YuYing Sun, JiaLin Zhang… in BMC Pediatrics (2024)

Article

Effect of dipeptidyl peptidase-4 inhibitors on tumor necrosis factor alpha levels in patients with type 2 diabetes mellitus

Dipeptidyl peptidase-4 inhibitors (DPP-4i) served as oral antidiabetic agents for treatment of type 2 diabetes mellitus (T2DM). Although an action on glucose homeostasis was identified, no well-rounded illustr...

Lijia Zhao, Jie Meng, Xueyan Bai, Donglei Zhang… in European Journal of Medical Research (2024)

Article

MICAL1 promotes the proliferation in acute myeloid leukemia and is associated with clinical prognosis and immune infiltration

Acute myeloid leukemia (AML) is one of the most common hematopoietic malignancies that has a poor prognosis and a high rate of relapse. Dysregulated metabolism plays an important role in AML progression. This ...

Yinsen Song, Zhenzhen Yang, Na Gao, Bojun Zhang in Discover Oncology (2024)

Article

Temporal relationship between hepatic steatosis and fasting blood glucose elevation: a longitudinal analysis from China and UK

The link between nonalcoholic fatty liver disease and type 2 diabetes has not been fully established. We investigated the temporal relationship between nonalcoholic fatty liver disease (NAFLD) and type 2 diabe...

Yujie Liu, **an Liang, Yifan Hu, Ning Zhang, **ngren Zhu, Yuemei Feng… in BMC Public Health (2024)

Article

Fat Mass and Obesity-Associated Protein Regulates Granulosa Cell Aging by Targeting Matrix Metalloproteinase-2 Gene Via an N6-Methyladenosine-YT521-B Homology Domain Family Member 2-Dependent Pathway in Aged Mice

In this study, we aimed to investigate the molecular mechanisms of RNA N6-methyladenosine (m6A) modification and how its associated proteins affect granulosa cell aging. A granulosa cell senescence model was c...

Linshuang Li, Le Yang, Lin Shen, Yiqing Zhao, Lan Wang… in Reproductive Sciences (2024)