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Article
Open AccessModular hemipelvic endoprosthesis with a sacral hook: a finite element study
A novel hemipelvic endoprosthesis with a sacral hook was introduced previously, and its clinical outcome with midterm follow-up showed decreased prosthesis-related complications, especially decreased rate of a...
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Article
Open AccessReconstruction with a novel combined hemipelvic endoprosthesis after resection of periacetabular tumors involving the sacroiliac joint: a report of 25 consecutive cases
Our purpose was to examine the outcomes of patients who underwent extensive resection of periacetabular tumors involving the sacroiliac joint and joint reconstruction with a hemipelvic endoprosthesis.
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Article
Comparative metagenomic sequencing analysis of cecum microbiotal diversity and function in broilers and layers
The composition of the gastrointestinal microorganisms in poultry is closely associated with the host and its environment. In this study, using 16S rRNA and metagenomic techniques, we comprehensively analyzed ...
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Article
Subgrain Effect on Grain Scale Plasticity of NiTi Shape Memory Alloy Under Canning Compression: A Crystal Plasticity Finite Element Analysis
The subgrain effect of NiTi shape memory alloy during canning compression at 400 °C is investigated through electron back-scattered diffraction (EBSD) experiment, transmission electron microscope (TEM) experim...
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Article
Influence of Extrusion Speed on the Microstructure Evolution, Interface Bonding and Mechanical Response of Mg MB26/Al 7075 Composite Rod
The Mg MB26/Al 7075 composite rod, in which Mg MB26 serves as the sleeve and Al 7075 serves as the core, is fabricated via the process of co-extrusion. The influence of extrusion speed on the microstructure ev...
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Article
Open AccessRobot-assisted sacral tumor resection: a preliminary study
Few studies have been done on robot-assisted sacral surgery. This study aims to evaluate the outcomes of seven patients with benign sacral or presacral tumors treated with a robotic surgical system at a single...
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Article
Open AccessPredictive value of dynamic change of haemoglobin levels during therapy on treatment outcomes in patients with Enneking stage IIB extremity osteosarcoma
We aimed to investigate the roles of hemoglobin (Hb) concentrations and dynamic change during treatment on outcomes of patients with extremity osteosarcoma.
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Article
Effects of Ausforming Procedure and Following Annealing Treatment on Microstructural Characteristics in Cobalt
The effects of ausforming procedure and subsequent annealing treatments on microstructures of cobalt (Co) samples are investigated by electron channeling contrast and electron backscatter diffraction technique...
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Article
Microstructural Characterization of Pure Titanium Treated by Laser Surface Treatment Under Different Processing Parameters
Advanced characterization techniques are utilized to investigate the effect of laser surface treatment on microstructural evolution of pure titanium (Ti). The results show that there are three distinctly diffe...
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Article
Microstructure and dry sliding wear behavior of laser clad AlCrNiSiTi multi-principal element alloy coatings
The approximately equimolar ratio AlCrNiSiTi multi-principal element alloy (MPEA) coatings were fabricated by laser cladding on Ti–6Al–4V (Ti64) alloy. Scanning electron microscopy (SEM), equipped with an ener...
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Stem Cell Transplantation in Diabetes Mellitus Type I and Type II
This chapter reviews significant advances in the transplantation of stem cell-derived insulin-producing cells in diabetes mellitus type I and type II. The successful outcome has been achieved in the standardiz...
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Stem Cell Therapy in Traumatic Brain Injury
Traumatic brain injury is one of the leading causes of major disability and death worldwide. Neural stem cells have recently been shown to contribute to the cellular remodelling that occurs following traumatic...
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Chapter
Stem Cell Therapy for Spinal Cord Injury
There is an urgent need for the effective treatment of individuals suffering from spinal cord injury (SCI). Advances in the understanding of stem cells have expanded pharmacotherapy to stem cell therapy for SC...
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Article
A novel combined hemipelvic endoprosthesis for peri-acetabular tumours involving sacroiliac joint: a finite element study
Our aim was to introduce a novel combined hemipelvic endoprosthesis for pelvic reconstruction after Enneking type I/II/IV resection and to evaluate the biomechanical properties of the endoprosthesis using fini...
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Article
Amyloid-β Activates Microglia and Regulates Protein Expression in a Manner Similar to Prions
Prions are the only convincingly demonstrated proteinaceous infectious particle, yet recent studies find that amyloid-β peptide (Aβ) aggregates are capable of self-propagation, which induces amyloidosis pathol...
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Article
Evolution of surface microstructure of Cu-50Cr alloy treated by high current pulsed electron beam
A Cu-50Cr alloy was treated by the high current pulsed electron beam (HCPEB) at 20 and 30 keV with pulse numbers ranging from 1 to 100. Surface morphologies and microstructures of specimens before and after th...
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Article
Open AccessCoronavirus membrane-associated papain-like proteases induce autophagy through interacting with Beclin1 to negatively regulate antiviral innate immunity
Autophagy plays important roles in modulating viral replication and antiviral immune response. Coronavirus infection is associated with the autophagic process, however, little is known about the mechanisms of ...
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Article
Open AccessA bioinformatics method for predicting long noncoding RNAs associated with vascular disease
Long noncoding RNAs (lncRNAs) play important roles in human diseases including vascular disease. Given the large number of lncRNAs, however, whether the majority of them are associated with vascular disease re...
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Article
Open AccessDrug-repurposing identified the combination of Trolox C and Cytisine for the treatment of type 2 diabetes
Drug-induced gene expression dataset (for example Connectivity Map, CMap) represent a valuable resource for drug-repurposing, a class of methods for identifying novel indications for approved drugs. Recently, ...
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Article
PrP106-126 and Aβ1-42 Peptides Induce BV-2 Microglia Chemotaxis and Proliferation
Transmissible spongiform encephalopathies (TSEs) and Alzheimer's disease (AD) belong to a growing family of neurodegenerative disorders that is characterized by the generation of toxic protein aggregates in af...
