47 Result(s)

Article

Correction to: Influence of Extrusion Speed on the Microstructure Evolution, Interface Bonding and Mechanical Response of Mg MB26/Al 7075 Composite Rod

Yu Chen, Rui Zhang, Tao Zhou, Li Hu, Jian Tu… in Acta Metallurgica Sinica (English Letters) (2024)

Article

Construction of an ER stress-related prognostic signature for predicting prognosis and screening the effective anti-tumor drug in osteosarcoma

Osteosarcoma is the most common malignant primary bone tumor in infants and adolescents. The lack of understanding of the molecular mechanisms underlying osteosarcoma progression and metastasis has contributed...

Weidong Chen, Yan Liao, Pengxiao Sun, Jian Tu… in Journal of Translational Medicine (2024)

Article

Breaking solvation dominance of ethylene carbonate via molecular charge engineering enables lower temperature battery

Low temperatures severely impair the performance of lithium-ion batteries, which demand powerful electrolytes with wide liquidity ranges, facilitated ion diffusion, and lower desolvation energy. The keys lie i...

Yuqing Chen, Qiu He, Yun Zhao, Wang Zhou, Peitao **ao, Peng Gao… in Nature Communications (2023)

Article

Avian pathogenic Escherichia coli infection causes infiltration of heterophilic granulocytes of chick tracheal by the complement and coagulation cascades pathway

Avian pathogenic Escherichia coli (APEC) causes tracheal damage and heterophilic granulocytic infiltration and inflammation in infected chicks. In this study, we infected chick tracheal tissue with strain AE17 an...

Ziqi Li, Zhao Qi, **aoru Wang, Liting Lu, Haiyang Wang… in BMC Veterinary Research (2023)

Article

Network pharmacology and experimental verification-based strategy for exploring the mechanisms of luteolin in the treatment of osteosarcoma

Luteolin is an active ingredient in various traditional Chinese medicines for the treatment of multiple tumors. However, the mechanisms of its inhibitory effect on osteosarcoma proliferation and metastasis rem...

Renxuan Huang, Mingxian Xu, Weitang Guo, Mingzhe Cheng… in Cancer Cell International (2023)

Article

EspE3 plays a role in the pathogenicity of avian pathogenic Escherichia coli

APEC encodes multiple virulence factors that have complex pathogenic mechanisms. In this study, we report a virulence factor named EspE3, which can be secreted from APEC. This protein was predicted to have a l...

Qianwen Li, Zhao Qi, Dandan Fu, Bo Tang, **angjun Song, Ying Shao… in Veterinary Research (2023)

Article

Rewired m⁶A epitranscriptomic networks link mutant p53 to neoplastic transformation

N6-methyladenosine (m⁶A), one of the most prevalent mRNA modifications in eukaryotes, plays a critical role in modulating both biological and pathological processes. However, it is unknown whether mutant p53 neom...

An Xu, Mo Liu, Mo-Fan Huang, Yang Zhang, Ruifeng Hu… in Nature Communications (2023)

Article

Effector protein Hcp2a of avian pathogenic Escherichia coli interacts with the endoplasmatic reticulum associated RPL23 protein of chicken DF-1 fibroblasts

The type VI secretion system (T6SS) is a secretion apparatus widely found in pathogenic Gram-negative bacteria and is important for competition among various bacteria and host cell pathogenesis. Hcp is a core ...

Zhe Chen, Zhao Qi, Ziqi Li, Zichao Song, **aoru Wang, Ying Shao… in Veterinary Research (2023)

Article

Hcp2a of APEC affects mRNA splicing and protein quality control in DF-1 cells

Bacteria deliver effector proteins into the host cell via a secretory system that can directly act on the target to cause disease. As an important pipeline structural protein of the type VI secretion system (T...

**angjun Song, Zhe Chen, Ziqi Li, **aoru Wang, Manman Hou… in BMC Veterinary Research (2022)

Article

YqeH contributes to avian pathogenic Escherichia coli pathogenicity by regulating motility, biofilm formation, and virulence

Avian pathogenic Escherichia coli (APEC) is a pathotype of extraintestinal pathogenic E. coli and one of the most serious infectious diseases of poultry. It not only causes great economic losses to the poultry in...

Lei Yin, Baoyan Cheng, Jian Tu, Ying Shao, **angjun Song… in Veterinary Research (2022)

Article

Reverse transcription–enzymatic recombinase amplification coupled with CRISPR-Cas12a for rapid detection and differentiation of PEDV wild-type strains and attenuated vaccine strains

Porcine epidemic diarrhea virus (PEDV) is an enteric coronavirus that causes acute watery diarrhea and vomiting in unweaned piglets, and is associated with high mortality, thus causing severe economic losses i...

Kankan Yang, Yueqiao Liang, Yanan Li, Qi Liu… in Analytical and Bioanalytical Chemistry (2021)

Article

The circular RNA circ-ERBIN promotes growth and metastasis of colorectal cancer by miR-125a-5p and miR-138-5p/4EBP-1 mediated cap-independent HIF-1α translation

Circular RNA (circRNAs) and hypoxia have been found to play the key roles in the pathogenesis and progression of cancer including colorectal cancer (CRC). However, the expressions and functions of the specific...

Liang-Yan Chen, Lian Wang, Yue-**ang Ren, Zheng Pang, Yao Liu… in Molecular Cancer (2020)

Article

Evaluating metagenomics tools for genome binning with real metagenomic datasets and CAMI datasets

Shotgun metagenomics based on untargeted sequencing can explore the taxonomic profile and the function of unknown microorganisms in samples, and complement the shortage of amplicon sequencing. Binning assemble...

Yi Yue, Hao Huang, Zhao Qi, Hui-Min Dou, **n-Yi Liu, Tian-Fei Han… in BMC Bioinformatics (2020)

Article

N⁶-methyladenosine regulates glycolysis of cancer cells through PDK4

Studies on biological functions of N⁶-methyladenosine (m⁶A) modification in mRNA have sprung up in recent years. We find m⁶A can positively regulate the glycolysis of cancer cells. Specifically, m⁶A-sequencing an...

Zihan Li, Yanxi Peng, Jiexin Li, Zhuojia Chen, Feng Chen, Jian Tu… in Nature Communications (2020)