4,667 Result(s)

Article

Natural killer cell-derived exosome-based cancer therapy: from biological roles to clinical significance and implications

Natural killer (NK) cells are important immune cells in the organism and are the third major type of lymphocytes besides T cells and B cells, which play an important function in cancer therapy. In addition to ...

Chaohua Si, Jianen Gao, Xu Ma in Molecular Cancer (2024)

Article

Transcriptomics-based liquid biopsy panel for early non-invasive identification of peritoneal recurrence and micrometastasis in locally advanced gastric cancer

This study aimed to develop a novel six-gene expression biomarker panel to enhance the early detection and risk stratification of peritoneal recurrence and micrometastasis in locally advanced gastric cancer (L...

**’an Ding, Haotian Wu, Jiaxiang Wu… in Journal of Experimental & Clinical Cancer … (2024)

Article

Clinical evaluation of an artificial intelligence-assisted cytological system among screening strategies for a cervical cancer high-risk population

Primary cervical cancer screening and treating precancerous lesions are effective ways to prevent cervical cancer. However, the coverage rates of human papillomavirus (HPV) vaccines and routine screening are l...

Wen Yang, **angshu **, Liying Huang, Shufang Jiang, Jia Xu, Yurong Fu… in BMC Cancer (2024)

Article

Exhaled VOC detection in lung cancer screening: a comprehensive meta-analysis

Lung cancer (LC), characterized by high incidence and mortality rates, presents a significant challenge in oncology. Despite advancements in treatments, early detection remains crucial for improving patient ou...

**anzhe Fan, Ran Zhong, Hengrui Liang, Qiu Zhong, Hongtai Huang, Juan He… in BMC Cancer (2024)

Article

Comparison of the diagnostic value of various microRNAs in blood for colorectal cancer: a systematic review and network meta-analysis

Despite the existence of numerous studies investigating the diagnostic potential of blood microRNAs for colorectal cancer, the microRNAs under consideration vary widely, and comparative analysis of their diagn...

Jianhao Xu, Lanfen Pan, Dan Wu, Liqian Yao, Wenqian Jiang, Jiarui Min… in BMC Cancer (2024)

Article

Correction: Melatonin synergizes BRAF-targeting agent vemurafenib in melanoma treatment by inhibiting iNOS/hTERT signaling and cancer-stem cell traits

Jiaojiao Hao, Wenhua Fan, Yizhuo Li… in Journal of Experimental & Clinical Cancer … (2024)

Article

Correction to: Preclinical studies of Flonoltinib Maleate, a novel JAK2/FLT3 inhibitor, in treatment of JAK2^V617F-induced myeloproliferative neoplasms

Mengshi Hu, Tao Yang, Linyu Yang, Lu Niu, **bing Zhu, Ailin Zhao… in Blood Cancer Journal (2024)

Article

Quantitative parameter analysis of pretreatment dual-energy computed tomography in nasopharyngeal carcinoma cervical lymph node characteristics and prediction of radiotherapy sensitivity

Treatment efficacy may differ among patients with nasopharyngeal carcinoma (NPC) at similar tumor–node–metastasis stages. Moreover, end-of-treatment tumor regression is a reliable indicator of treatment sensit...

Zhiru Li, Chao Li, Liyan Li, Dong Yang, Shuangyue Wang, Junmei Song… in Radiation Oncology (2024)

Article

IKBIP promotes tumor development via the akt signaling pathway in esophageal squamous cell carcinoma

Esophageal squamous cell carcinoma (ESCC) is one of the most common cancers worldwide. Inhibitor of kappa B kinase interacting protein (IKBIP) has been reported to promote glioma progression, but its role in o...

Jiannan Hu, Chuan**g Dai, Zhaoji Ding, Yixiao Pan, Lingxiao Lu, Jiaqian Bao… in BMC Cancer (2024)

Article

Acute kidney injury in cancer patients receiving anti-vascular endothelial growth factor monoclonal antibody vs. immune checkpoint inhibitors: a retrospective real-world study

Anti-vascular endothelial growth factor monoclonal antibody (anti-VEGF) or immune checkpoint inhibitors (ICIs) combined with chemotherapy are commonly administered to cancer patients. Although cancer patients ...

Jianfen Zhu, **aokai Ding, Jianna Zhang, Bo Chen, **aohan You, **nxin Chen… in BMC Cancer (2024)

Article

The safety and efficacy of volumetric modulated Arc therapy combined with computer tomography-guided adaptive brachytherapy for locally advanced cervical cancer: a single institution experience

Volumetric modulated arc therapy (VMAT) is a novel form of IMRT, which can deliver more accurate dose distribution and shorten treatment time. Compared to MRI-guided adaptive brachytherapy, which is recommende...

Tianyu Yang, Tiandi Zhao, Zhe Ji, Runhong Lei, Ang Qu, Weijuan jiang… in Radiation Oncology (2024)

Article

QL1209 (pertuzumab biosimilar) versus reference pertuzumab plus trastuzumab and docetaxel in neoadjuvant treatment for HER2-positive, ER/PR-negative, early or locally advanced breast cancer: A multicenter, randomized, double-blinded, parallel-controlled, phase III equivalence trial

This randomized, parallel-controlled, double-blinded, phase III equivalence study evaluated the equivalence of a proposed pertuzumab biosimilar QL1209 to the pertuzumab (Perjeta®) each with trastuzumab and doc...

Wenjia Zuo, Zhonghua Wang, Jun Qian, **aopeng Ma, Zhaofeng Niu… in British Journal of Cancer (2024)

Article

Genetically evaluating the causal role of peripheral immune cells in colorectal cancer: a two-sample Mendelian randomization study

Investigating novel therapeutic strategies for colorectal cancer (CRC) is imperative. However, there is limited research on the use of drugs to target peripheral blood immune cells in this context. To address ...

Runze Huang, **n **, Ziting Jiang, Yixiu Wang, Yibin Wu, Lu Wang… in BMC Cancer (2024)

Article

The immunotoxin targeting PRLR increases tamoxifen sensitivity and enhances the efficacy of chemotherapy in breast cancer

Though tamoxifen achieves success in treating estrogen receptor α (ERα)-positive breast cancer, the followed development of tamoxifen resistance is a common challenge in clinic. Signals downstream of prolactin...

Jiawei Zhang, Junjun Liu, Yali Yue, Lei Wang… in Journal of Experimental & Clinical Cancer … (2024)

Article

Correction: Inhibition of MTA1 by ERα contributes to protection hepatocellular carcinoma from tumor proliferation and metastasis

Lei Deng, Hui Yang, Junwei Tang, Zhe Lin… in Journal of Experimental & Clinical Cancer … (2024)

Article

Circ6834 suppresses non-small cell lung cancer progression by destabilizing ANHAK and regulating miR-873-5p/TXNIP axis

Circular RNAs (circRNAs) play important roles in cancer progression and metastasis. However, the expression profiles and biological roles of circRNAs in non-small cell lung cancer (NSCLC) remain unclear.

Maoye Wang, **aoge Ding, **njian Fang, **g Xu, Yanke Chen, Yu Qian… in Molecular Cancer (2024)

Article

CDK4/6 inhibitors dephosphorylate RNF26 to stabilize TSC1 and increase the sensitivity of ccRCC to mTOR inhibitors

The combined use of CDK4/6 inhibitors and mTOR inhibitors has achieved some clinical success in ccRCC. Exploring the underlying mechanism of the CDK4/6 pathway in cancer cells and the drug interactions of CDK4...

**nlin Liu, Wei Li, Lu Yi, Jianxi Wang, Wentao Liu… in British Journal of Cancer (2024)

Article

Multi-omics profiling reveal cells with novel oncogenic cluster, TRAP1^low/CAMSAP3^low, emerge more aggressive behavior and poor-prognosis in early-stage endometrial cancer

The clinical heterogeneity of early-stage endometrial cancer (EC) is worthy of further study to identify high-quality prognostic markers and their potential role in aggressive tumor behavior. Mutation of TP53 ...

**aodan Mao, **aoyue Tang, **gxuan Ye, Shuxia Xu, Yue Wang… in Molecular Cancer (2024)