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  1. Article

    Open Access

    SMRT sequencing revealed to be an effective method for ADTKD-MUC1 diagnosis through follow-up analysis of a Chinese family

    We reported a large Chinese family diagnosed with autosomal dominant tubulointerstitial kidney disease caused by MUC1 mutation (ADTKD-MUC1). Cytosine duplication within a string of 7 cytosines in the variable-num...

    Guo-qin Wang, Hong-liang Rui, Hong-rui Dong, Li-jun Sun, Min Yang in Scientific Reports (2020)

  2. Article

    Open Access

    3D-printed model-guided endoscopic evacuation for basal ganglia hemorrhage

    The purpose of this study was to investigate the effectiveness and practicality of 3D-printed model-guided endoscopic surgery for the treatment of basal ganglia hemorrhage. The authors retrospectively analyzed...

    Jun Zhang, Hongyu Cheng, Sitong Zhou, Li** Huang, Jianguang Lv in Scientific Reports (2020)

  3. Article

    Open Access

    Care Practices, Morbidity and Mortality of Preterm Neonates in China, 2013–2014: a Retrospective study

    This retrospective cohort study aimed to investigate the prevalence, morbidity, mortality and the maternal/neonatal care of preterm neonates and the perinatal risk factors for mortality. We included data on 13...

    Fengdan Xu, **angyong Kong, Shunyan Duan, Hongyan Lv, Rong Ju in Scientific Reports (2019)

  4. Article

    Open Access

    BTLA suppress acute rejection via regulating TCR downstream signals and cytokines production in kidney transplantation and prolonged allografts survival

    Acute rejection is a major risk for renal transplant failure. During this adverse process, activated T cells are considered the main effectors. Recently, B and T lymphocyte attenuator (BTLA), a member of the C...

    Jiayi Zhang, Hengcheng Zhang, Zijie Wang, Haiwei Yang, Hao Chen in Scientific Reports (2019)

  5. Article

    Open Access

    The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression

    The interactions between tumor cells with their microenvironments, including hypoxia, acidosis and immune cells, lead to the tumor heterogeneity which promotes tumor progression. Here, we show that SIAH2-NRF1 ...

    Biao Ma, Hongcheng Cheng, Chenglong Mu, Guangfeng Geng, Tian Zhao in Nature Communications (2019)

  6. Article

    Open Access

    Contributions of modern Gobi Desert to the Badain Jaran Desert and the Chinese Loess Plateau

    It is well known that the Gobi Desert is the dominant source area of the Badain Jaran Desert (BJD) and the Chinese Loess Plateau (CLP). However, due to the absence of quantitative analyses, there are nearly no...

    Xunming Wang, Diwen Cai, Jimin Sun, Huayu Lu, Wenbin Liu in Scientific Reports (2019)

  7. Article

    Open Access

    The dynamic transcriptome and metabolomics profiling in Verticillium dahliae inoculated Arabidopsis thaliana

    Verticillium wilt caused by the soil-borne fungus Verticillium dahliae is a common, devastating plant vascular disease notorious for causing economic losses. Despite considerable research on plant resistance gene...

    **aofeng Su, Guoqing Lu, Huiming Guo, Kaixuan Zhang, **aokang Li in Scientific Reports (2018)

  8. Article

    Open Access

    Author Correction: An intercross population study reveals genes associated with body size and plumage color in ducks

    In the original version of this Article, there was an error in the legend for Figure 2, whereby the descriptions of panels a, b and c were presented in a different order to the corresponding figure panels. The...

    Zhengkui Zhou, Ming Li, Hong Cheng, Wenlei Fan, Zhengrong Yuan in Nature Communications (2018)

  9. Article

    Open Access

    An intercross population study reveals genes associated with body size and plumage color in ducks

    Comparative population genomics offers an opportunity to discover the signatures of artificial selection during animal domestication, however, their function cannot be directly revealed. We discover the select...

    Zhengkui Zhou, Ming Li, Hong Cheng, Wenlei Fan, Zhengrong Yuan in Nature Communications (2018)

  10. Article

    Open Access

    aPKCζ-dependent Repression of Yap is Necessary for Functional Restoration of Irradiated Salivary Glands with IGF-1

    Xerostomia and salivary hypofunction often result as a consequence of radiation therapy for head and neck cancers, which are diagnosed in roughly 60,000 individuals every year in the U.S. Due to the lack of ef...

    Alejandro M. Chibly, Wen Yu Wong, Maricela Pier, Hongqiang Cheng in Scientific Reports (2018)

  11. Article

    Open Access

    Publisher Correction: Role of outer surface probes for regulating ion gating of nanochannels

    The original version of this Article contained an error in Fig. 3. The scale bars in Figs 3c and 3d were incorrectly labelled as 50 μA. In the correct version, the scale bars are labelled as 0.5 μA. This has n...

    **nchun Li, Tianyou Zhai, Pengcheng Gao, Hongli Cheng, Ruizuo Hou in Nature Communications (2018)

  12. Article

    Open Access

    Association of S100B polymorphisms and serum S100B with risk of ischemic stroke in a Chinese population

    The levels of serum S100B were elevated in patients with ischemic stroke (IS), which may be a novel biomarker for diagnosing IS. The aim of this study was to investigate the association of S100B polymorphisms and...

    Yu-Lan Lu, Rong Wang, Hua-Tuo Huang, Hai-Mei Qin, Chun-Hong Liu in Scientific Reports (2018)

  13. Article

    Open Access

    Biochemical and genetic characterization of a novel metallo-β-lactamase from marine bacterium Erythrobacter litoralis HTCC 2594

    Metallo-β-lactamases (MBLs) are a group of enzymes that can inactivate most commonly used β-lactam-based antibiotics. Among MBLs, New Delhi metallo-β-lactamase-1 (NDM-1) constitutes an urgent threat to public ...

    **a-Wei Jiang, Hong Cheng, Ying-Yi Huo, Lin Xu, Yue-Hong Wu in Scientific Reports (2018)

  14. Article

    Open Access

    Role of outer surface probes for regulating ion gating of nanochannels

    Nanochannels with functional elements have shown promise for DNA sequencing, single-molecule sensing, and ion gating. Ionic current measurement is currently a benchmark, but is focused solely on the contributi...

    **nchun Li, Tianyou Zhai, Pengcheng Gao, Hongli Cheng, Ruizuo Hou in Nature Communications (2018)

  15. Article

    Open Access

    Demonstration of ultra-high recyclable energy densities in domain-engineered ferroelectric films

    Dielectric capacitors have the highest charge/discharge speed among all electrical energy devices, but lag behind in energy density. Here we report dielectric ultracapacitors based on ferroelectric films of Ba(Zr

    Hongbo Cheng, Jun Ouyang, Yun-**ang Zhang, David Ascienzo, Yao Li in Nature Communications (2017)

  16. Article

    Open Access

    Genome characterization of two bile-isolated Vibrio fluvialis strains: an insight into pathogenicity and bile salt adaption

    Vibrio fluvialis is recognized as an emerging pathogen. However, not much is known about the mechanism of its pathogenesis, and its adaptation to a special niche such as the gall bladder....

    Beiwen Zheng, **awei Jiang, Hong Cheng, Lihua Guo, **g Zhang, Hao Xu in Scientific Reports (2017)

  17. Article

    Open Access

    Modern dust aerosol availability in northwestern China

    The sources of modern dust aerosols and their emission magnitudes are fundamental for linking dust with climate and environment. Using field sample data, wind tunnel experiments and statistical analysis, we de...

    Xunming Wang, Hong Cheng, Huizheng Che, Jimin Sun, Huayu Lu in Scientific Reports (2017)

  18. Article

    Open Access

    Key driving forces of desertification in the Mu Us Desert, China

    The temporal trends and key driving forces of desertification in the Mu Us Desert are representatives of most arid regions of Asia with a high risk of desertification. We analyzed the significance of Aeolian t...

    Xunming Wang, Hong Cheng, Hui Li, Junpeng Lou, Ting Hua, Wenbin Liu in Scientific Reports (2017)

  19. Article

    Open Access

    In–situ XRD and EDS method study on the oxidation behaviour of Ni–Cu sulphide ore

    The oxidation mechanism of sulfides is the key issue during the sulphide–metallurgy process. In this study, the phase transformation and element migration were clearly demonstrated by in–situ laboratory–based ...

    Guangshi Li, Hongwei Cheng, **aolu **ong, **onggang Lu, Cong Xu in Scientific Reports (2017)

  20. Article

    Open Access

    Impact of genotype on endocrinal complications of Children with Alpha-thalassemia in China

    Alpha-thalassemia occurs with high frenquency in China. Four common α-globin gene deletion mutations (–SEA, -α3.7, and -α4.2, Haemoglobin Constant Spring (CS) mutation) were identified in Chinese patients. Ind...

    Hong-Cheng Luo, Qi-Sheng Luo, Fu-Gao Huang, Chun-Fang Wang in Scientific Reports (2017)

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