56 Result(s)

Article

Changes in procalcitonin and presepsin before and after immunoglobulin administration in septic patients

T Ikeda, S Ono, T Ueno, H Tanaka, S Suda in Critical Care (2015)

Article

PARVB overexpression increases cell migration capability and defines high risk for endophytic growth and metastasis in tongue squamous cell carcinoma

Tongue squamous cell carcinoma (TSCC) is highly diverse, even in its early stages. This cancer is classified into three subtypes (superficial, exophytic, and endophytic) based on macroscopic appearance. Of the...

A Eslami, K Miyaguchi, K Mogushi, H Watanabe, N Okada… in British Journal of Cancer (2015)

Article

NF-κB-dependent and -independent epigenetic modulation using the novel anti-cancer agent DMAPT

The transcription factor nuclear factor-kappaB (NF-κB) is constitutively active in several cancers and is a target of therapeutic development. We recently developed dimethylaminoparthenolide (DMAPT), a clinical g...

H Nakshatri, H N Appaiah, M Anjanappa, D Gilley, H Tanaka, S Badve… in Cell Death & Disease (2015)

Article

Physical impairment and walking function required for community ambulation in patients with cervical incomplete spinal cord injury

Cross-sectional study.

T Hasegawa, Y Uchiyama, K Uemura, Y Harada, M Sugiyama, H Tanaka in Spinal Cord (2014)

Article

Quantifying degree of foot use impairment in hemiplegic gait using center-of-pressure trajectory vector difference integrals

TC Pataky, H Tanaka, M Hashimoto in Journal of Foot and Ankle Research (2014)

Article

Benefit profile of recombinant human soluble thrombomodulin in sepsis-induced DIC

K Yamakawa, H Ogura, S Fujimi, M Morikawa, Y Ogawa, Y Umemura, Y Inoue… in Critical Care (2014)

Article

Factors involved in prolonged effect of neuromuscular blockade in therapeutic hypothermia

H Tanaka, T Mochizuki, S Ode, S Ishimatsu in Critical Care (2014)

Article

Landscape of genetic lesions in 944 patients with myelodysplastic syndromes

High-throughput DNA sequencing significantly contributed to diagnosis and prognostication in patients with myelodysplastic syndromes (MDS). We determined the biological and prognostic significance of genetic a...

T Haferlach, Y Nagata, V Grossmann, Y Okuno, U Bacher, G Nagae, S Schnittger… in Leukemia (2014)

Article

Circulating microRNAs as biomarkers for early detection of diffuse-type gastric cancer using a mouse model

Diffuse-type gastric cancer (DGC) exhibits rapid disease progression and a poor prognosis. There are no effective serum biomarkers for early detection of DGC. We have established an E-cadherin/p53 double condi...

P Rotkrua, S Shimada, K Mogushi, Y Akiyama, H Tanaka, Y Yuasa in British Journal of Cancer (2013)

Article

Increasing Si photodetector photosensitivity in near-infrared region and manifestation of optical amplification by dressed photons

We fabricated a novel photodetector by subjecting a Si crystal having a p–n homojunction to phonon-assisted annealing. The photosensitivity of this device for incident light having a wavelength of 1.16 μm or g...

H. Tanaka, T. Kawazoe, M. Ohtsu in Applied Physics B (2012)

Article

Expression of Forkhead box P3 in tumour cells causes immunoregulatory function of signet ring cell carcinoma of the stomach

It was recently reported that the transcription factor Forkhead box P3 (FoxP3) is expressed not only in regulatory T cells (Tregs) but also in cancer cells. The aim of this study was to clarify the clinical si...

M Yoshii, H Tanaka, M Ohira, K Muguruma, T Iwauchi, T Lee… in British Journal of Cancer (2012)

Article

¹³C-phenylalanine breath test detects altered phenylalanine kinetics in schizophrenia patients

Phenylalanine is an essential amino acid required for the synthesis of catecholamines including dopamine. Altered levels of phenylalanine and its metabolites in blood and cerebrospinal fluid have been reported...

T Teraishi, Y Ozeki, H Hori, D Sasayama, S Chiba, N Yamamoto… in Translational Psychiatry (2012)

Article

Acquisition of EMT phenotype in the gefitinib-resistant cells of a head and neck squamous cell carcinoma cell line through Akt/GSK-3β/snail signalling pathway

Epithelial mesenchymal transition (EMT) is known to be associated with chemoresistance as well as increased invasion/metastasis. However, the relationship between EMT and resistance to an epidermal growth fact...

S Maseki, K Ijichi, H Tanaka, M Fujii, Y Hasegawa, T Ogawa… in British Journal of Cancer (2012)

Article

Effect of age on bowel management in traumatic central cord syndrome

A retrospective multicenter study.

K Furusawa, A Tokuhiro, A Ikeda, F Tajima, R Uchida, T Tominaga, H Tanaka… in Spinal Cord (2012)

Article

Incidence of symptomatic autonomic dysreflexia varies according to the bowel and bladder management techniques in patients with spinal cord injury

A retrospective, multicenter study.

K Furusawa, A Tokuhiro, H Sugiyama, A Ikeda, F Tajima, E Genda, R Uchida… in Spinal Cord (2011)

Article

Pinwheel valence-bond solid and triplet excitations in the two-dimensional deformed kagome lattice

Single crystals of a two-dimensional quantum spin system with geometric frustration lead to the observation of a ‘pinwheel’ valence-bond ground state. In this case, the distortion of the ideal kagome lattice s...

K. Matan, T. Ono, Y. Fukumoto, T. J. Sato, J. Yamaura, M. Yano, K. Morita… in Nature Physics (2010)

Article

Increased circulating cell signalling phosphoproteins in sera are useful for the detection of pancreatic cancer

Intracellular phosphoprotein activation significantly regulates cancer progression. However, the significance of circulating phosphoproteins in the blood remains unknown. We investigated the serum phosphoprote...

S Takano, K Sogawa, H Yoshitomi, T Shida, K Mogushi, F Kimura… in British Journal of Cancer (2010)

Article

Oestrogen receptor-α contributes to the regulation of the hedgehog signalling pathway in ERα-positive gastric cancer

Oestrogen receptor-alpha (ERα) is highly expressed in diffuse-type gastric cancer and oestrogen increases the proliferation of ERα-positive gastric cancer. However, a detailed mechanism by which oestrogen increas...

C Kameda, M Nakamura, H Tanaka, A Yamasaki, M Kubo, M Tanaka… in British Journal of Cancer (2010)

Article

The Bcr-Abl kinase inhibitor INNO-406 induces autophagy and different modes of cell death execution in Bcr-Abl-positive leukemias

Bcr-Abl tyrosine kinase (TK) inhibitors are promising therapeutic agents for Bcr-Abl-positive (Bcr-Abl⁺) leukemias. Although they are known to promote caspase-mediated apoptosis, it remains unclear whether caspas...

Y Kamitsuji, J Kuroda, S Kimura, S Toyokuni, K Watanabe… in Cell Death & Differentiation (2008)

Article

Two-photon probe of the Jaynes–Cummings model and controlled symmetry breaking in circuit QED

Micrometre-scale superconducting circuits can act as quantum two-level systems, but unlike in their natural counterparts—such as atoms—the parameters of these ‘artificial qubits’ can be controlled externally. ...

Frank Deppe, Matteo Mariantoni, E. P. Menzel, A. Marx, S. Saito… in Nature Physics (2008)