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Article
Cancer stem cell markers are associated with adverse biomarker profiles and molecular subtypes of breast cancer
Cumulative evidence has demonstrated the presence of cancer stem cells (CSC) in breast cancer and its putative role in cancer progression. Nonetheless, the clinical significance of CSC in breast cancer remains...
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Article
Keratin expression in breast cancers
Cytokeratin (CK) immunohistochemistry can play an important role in breast carcinoma evaluation. We evaluated the expression of a panel of commonly used CKs in a large cohort of breast cancers and assessed its...
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Article
Biopsy sampling of breast lesions: comparison of core needle- and vacuum-assisted breast biopsies
Needle biopsy is now the initial investigation of choice for the pre-operative diagnosis of breast lesions. This includes core needle biopsy (CNB) and vacuum-assisted biopsy (VAB) with or without radiologic as...
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Article
A subset of breast cancer predisposes to brain metastasis
This study evaluated the expression of biological markers of breast cancers with brain metastases. Eighteen paired tumors were assessed, with 42 non-brain-metastasizing breast cancers that were stained with ER...
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Article
Diagnosing breast lesions by fine needle aspiration cytology or core biopsy: which is better?
Fine needle aspiration cytology (FNAC) and core needle biopsy (CNB) are widely used in diagnosing breast lesions, with both achieving high sensitivity and specificity. Whether FNAC or CNB is better remains hig...
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Article
Breast cancer prognostic classification in the molecular era: the role of histological grade
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Article
Intermediate to highly suspicious calcification in breast lesions: a radio-pathologic correlation
Breast calcification is an important feature in the radiological assessment of breast lesions. There are well established diagnostic criteria basing on the morphology and distribution of the calcifications rad...
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Article
In vivo proton magnetic resonance spectroscopy of breast lesions: an update
In vivo proton magnetic resonance spectroscopy (1H-MRS) has been demonstrated to be successful in the differentiation of benign and malignant breast lesions in a non-invasive manner by detecting increased levels ...