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Article
Open AccessPossible prevention of uremic nausea by vitamin D receptor activators in non-dialysis patients with stage 5 chronic kidney disease
Nausea is a major uremic symptom and a frequent indication for starting dialysis. However, preventive medication for uremic nausea has not yet been identified. Vitamin D receptor activators (VDRAs) may prevent...
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Article
Open AccessRelationship between mortality and Geriatric Nutritional Risk Index (GNRI) at the time of dialysis initiation: a prospective multicenter cohort study
The Geriatric Nutritional Risk Index (GNRI) is a nutritional screening method primarily developed for elderly people; it is also reported to be useful for predicting mortality in patients on maintenance dialys...
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Article
Open AccessRisk factors for CKD progression in Japanese patients: findings from the Chronic Kidney Disease Japan Cohort (CKD-JAC) study
Chronic kidney disease (CKD) eventually progresses to end-stage renal disease (ESRD). However, risk factors associated with CKD progression have not been well characterized in Japanese patients with CKD who ar...
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Article
Physical function at the time of dialysis initiation is associated with subsequent mortality
In dialysis patients, physical function is associated with mortality. However, the association between physical function at the time of dialysis initiation and subsequent mortality remains unknown.
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Article
Open AccessEffect of continuous hemodiafiltration using an AN69ST membrane in patients with sepsis
Sepsis is a systemic inflammatory response syndrome caused by infectious disease. Severe sepsis and septic shock are extremely serious conditions with poor prognoses. It is reported that cytokines are deeply i...
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Article
Open AccessRelationship between history of coronary heart disease at dialysis initiation and onset of events associated with heart disease: a propensity-matched analysis of a prospective cohort study
Chronic kidney disease (CKD) is an independent risk factor for cardiovascular disease (CVD) events, and a number of reports have shown a relationship between CKD and CVD in pre-dialysis or maintenance dialysis...
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Article
Relationship between mortality and speed of eGFR decline in the 3 months prior to dialysis initiation
The timing for initiating dialysis in chronic kidney disease is often determined by the clinical symptoms and estimated glomerular filtration rate (eGFR). However, very few studies have examined how the speed ...
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Article
Open AccessRelationship between serum calcium level at dialysis initiation and subsequent prognosis
In patients on maintenance dialysis, increased serum calcium levels are known to be associated with a poor prognosis. However, it is not known whether serum calcium levels at dialysis initiation have an impact...
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Article
Open AccessFactors associated with early failure of vascular access in acute-phase patients
Acute-phase patients sometimes require hemodialysis therapy without vascular access (VA) present on admission. These patients require VA creation to continue hemodialysis after discharge. The risk of early VA ...
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Article
Open AccessRisk factors for acute kidney injury after initial acute aortic dissection and their effect on long-term mortality
Several reports have discussed the risk factors for acute kidney injury (AKI) after thoracic aortic surgery and aortic dissection and the increased mortality in patients with AKI. However, there are few report...
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Article
Aichi cohort study of the prognosis in patients newly initiated into dialysis (AICOPP): baseline characteristics and trends observed in diabetic nephropathy
Over 300,000 patients receive maintenance dialysis in Japan; managing these patients is extremely important. This study aimed to report on prior management of chronic kidney diseases and prognostication after ...
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Article
Open AccessEffect of long-acting erythropoiesis-stimulating agents on hemoglobin levels at the initiation of dialysis
The goal of the present study was to explore the differences in effects between erythropoiesis-stimulating agent (ESA) types on hemoglobin (Hb) level at the initiation of maintenance dialysis.
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Article
Ability of vitamin D receptor activator to prevent pulmonary congestion in advanced chronic kidney disease
Vitamin D deficiency is common among patients with chronic kidney disease (CKD). However, the benefits of vitamin D supplementation versus vitamin D receptor activator (VDRA) administration have yet to be esta...
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Article
Beneficial effects of preemptive kidney transplantation on calcium and phosphorus disorders in early post-transplant recipients
Recently, preemptive kidney transplantation (PKT) has increased in Japan; however, the effects of PKT on calcium (Ca) and phosphorus (Pi) metabolism are poorly understood.
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Article
How to estimate kidney function in kidney transplant recipients with mild to moderate kidney impairment: comparison of estimated glomerular filtration (eGFR) values between creatinine-based GFR equations and cystatin C-based GFR equations for Japanese population
With the recent increase in renal transplantations in Japan, accurate assessment of renal function is required.
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Article
Open AccessEffect of erythropoietin-stimulating agent on uremic inflammation
The goal of the present study was to explore the effect of medications that are commonly prescribed for CKD patients on uremic state.
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Article
Influence of renin–angiotensin system on serum parathyroid hormone levels in uremic patients
The aim of this study was to investigate the factors influencing serum parathyroid (PTH) levels, including medications for treating chronic kidney disease–mineral and bone metabolism disorder (CKD-MBD) in pati...
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Article
Nephrologist care for 12 months or more increases hemodialysis initiation with permanent vascular access
The objective of this study was to evaluate the effect of early referral (ER) to nephrologists on the type of vascular access (VA) available for use at the time of initiation of maintenance hemodialysis (HD). ...
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Article
Peritonitis is still an important factor for withdrawal from peritoneal dialysis therapy in the Tokai area of Japan
In Japan, the population of patients on peritoneal dialysis (PD) is <4% of the total number of patients with end-stage renal disease. Few systemic analyses have examined why the number of PD patients has not i...
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Article
Intravenously administered darbepoetin alfa once a week could maintain hemoglobin level more efficiently than once every 2 weeks in patients on hemodialysis
Darbepoetin alfa, which has a much longer half-life than recombinant human erythropoietin, is used to treat renal anemia. However, there are few reports investigating the efficacy of darbepoetin alfa administe...
