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Article
Open AccessSodium-glucose cotransporter 2 inhibitor versus metformin as first-line therapy in patients with type 2 diabetes mellitus: a multi-institution database study
Sodium-glucose co-transporter 2 inhibitors (SGLT2i) has shown evidence of cardiovascular benefit in patients with type 2 diabetes mellitus (T2DM). Currently metformin is the guideline-recommended first-line tr...
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Article
Open AccessAssociation between regional economic status and renal recovery of dialysis-requiring acute kidney injury among critically ill patients
The association between regional economic status and the probability of renal recovery among patients with dialysis-requiring AKI (AKI-D) is unknown. The nationwide prospective multicenter study enrolled criti...
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Article
Open AccessAcute kidney disease and acute kidney injury biomarkers in coronary care unit patients
Acute kidney disease (AKD) describes acute or subacute damage and/or loss of kidney function for a duration of between 7 and 90 days after exposure to an acute kidney injury (AKI) initiating event. This study ...
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Article
Open AccessAssociation between initial dialytic modalities and the risks of mortality, infection death, and cardiovascular events: A nationwide population-based cohort study
To date, few studies have been conducted to pairwise compare the prognosis of peritoneal dialysis (PD), unplanned PD, and unplanned hemodialysis (HD). We analyzed longitudinal data from Taiwan’s National Healt...
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Article
Open AccessFurosemide stress test as a predictive marker of acute kidney injury progression or renal replacement therapy: a systemic review and meta-analysis
The use of the furosemide stress test (FST) as an acute kidney injury (AKI) severity marker has been described in several trials. However, the diagnostic performance of the FST in predicting AKI progression ha...
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Article
Open AccessComparison between watchful waiting strategy and early initiation of renal replacement therapy in the critically ill acute kidney injury population: an updated systematic review and meta-analysis
The optimal timing of renal replacement therapy (RRT) initiation is debatable. Many articles in this field enrolled trials not based on acute kidney injury. The safety of the watchful waiting strategy has not ...
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Article
Open AccessInfection in Advanced Chronic Kidney Disease and Subsequent Adverse Outcomes after Dialysis Initiation: A Nationwide Cohort Study
It remains unclear whether infection events before entering end stage renal disease (ESRD) have a long-term negative impact on patients with advanced chronic kidney disease (CKD) who survive to permanent dialy...
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Article
Open AccessInfluence of extension stem length and diameter on clinical and radiographic outcomes of revision total knee arthroplasty
Extension stems provide stability to revision total knee arthroplasty (RTKA). Little is known regarding the relationship between stem characteristics and RTKA stability. We aimed to identify the relationship b...
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Article
Mitochondrial lipoylation integrates age-associated decline in brown fat thermogenesis
Thermogenesis in brown adipose tissue (BAT) declines with age; however, what regulates this process is poorly understood. Here, we identify mitochondrial lipoylation as a previously unappreciated molecular hal...
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Article
Open AccessAnalysis of survival after initiation of continuous renal replacement therapy in patients with extracorporeal membrane oxygenation
No study has specifically investigated the duration of continuous renal replacement therapy (CRRT) in patients who experienced acute kidney injury during extracorporeal membrane oxygenation (ECMO) support. How...
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Article
Open AccessPrognostic value of endothelial biomarkers in refractory cardiogenic shock with ECLS: a prospective monocentric study
Extracorporeal membrane oxygenation (ECMO) is often used in critical patients with severe myocardial failure. However, the mortality rate of patients on ECMO is often high. Recent studies have suggested that e...
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Article
Open AccessA circulating miRNA signature for early diagnosis of acute kidney injury following acute myocardial infarction
Acute kidney injury (AKI) is a common complication of acute myocardial infarction (AMI), and is associated with adverse outcomes. The study aimed to identify a miRNA signature for the early diagnosis of post-A...
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Article
A Time Integration Method for Phase-Field Modeling
A novel numerical time integration for solving phase-field problems is presented. This method includes the generalized single step single solve (GSSSS) family of algorithms, which can preserve second-order tim...
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Article
Open AccessBretschneider solution-induced alterations in the urine metabolome in cardiac surgery patients
The development of Bretschneider’s histidine-tryptophan-ketoglutarate (HTK) cardioplegia solution represented a major advancement in cardiac surgery, offering significant myocardial protection. However, metabo...
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Article
Parametric study of surface morphology for selective laser melting on Ti6Al4V powder bed with numerical and experimental methods
A three-dimensional (3D) selective laser melting (SLM) model comprising coupled heat transfer and flow behavior is proposed. The free surface of the melt pool is calculated by the volume-of-fluid (VOF) method,...
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Article
Open AccessA combination of SOFA score and biomarkers gives a better prediction of septic AKI and in-hospital mortality in critically ill surgical patients: a pilot study
Sepsis is a syndrome characterized by a constellation of clinical manifestations and a significantly high mortality rate in the surgical intensive care unit (ICU). It is frequently complicated by acute kidney ...
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Article
Fast J-linkage algorithm for camera orientation applications
A computationally efficient approach to obtain vanishing points in images for camera orientation applications is presented in this paper. Modifications are made to the conventional J-linkage algorithm, named F...
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Outcome of Total Hip Arthroplasty in Patients with Dysplasia/Dislocation and Planning for Revision
The reported outcomes of total hip arthroplasty (THA) for developmental dysplasia of the hip (DDH) varied widely because a wide range of deformities were included and different treating protocols and different...
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Article
Open AccessRed cell distribution width associated with adverse cardiovascular outcomes in patients with chronic kidney disease
Recent studies have demonstrated that red cell distribution width (RDW) is associated with cardiovascular (CV) events and mortality. Patients with chronic kidney disease (CKD) are often anemic and have high RD...
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Article
Open AccessAdd-on neurological benefits of antiviral therapy in HCV patients with chronic kidney disease — a nationwide cohort study
Hepatitis C virus (HCV)-infected patients with chronic kidney disease (CKD) have rarely been studied because they rarely accept interferon-based therapy (IBT) and have been difficult to follow up. We investiga...
