-
Article
Use and perception of Internet for health related purposes in Germany: results of a national survey
Patient empowerment through the Internet is seen as a chance to improve patient-physician communication. Studies on the prevalence of Internet use for health related purposes and on how patients perceive those...
-
Article
Diagnostic value of multifocal VEP using cross-validation and noise reduction in glaucoma research
The diagnostic value of multifocal visual evoked potentials (mf VEP) in glaucoma research is still under debate. Several previous studies proclaim it to be a useful tool for clinical applications, but accordin...
-
Article
Results and complications of hydrophobic acrylic vs PMMA posterior chamber lenses in children under 17 years of age
To compare results and complications of implantation of hydrophobic acrylic foldable intraocular lenses in children with those of polymethylmethacrylate (PMMA) intraocular lenses.
-
Chapter and Conference Paper
Automated Segmentation of the Optic Nerve Head for Glaucoma Diagnosis
The diagnosis of glaucoma is closely associated with a morphological change in the optic nerve head (ONH), which can be examined with a scanning laser ophthalmoskop (Heidelberg Retina Tomograph). In this contr...
-
Chapter and Conference Paper
Glaucoma Diagnosis by Indirect Classifiers
Medical decision making is based on various diagnostic measurements and the evaluation of anamnestic information. For example glaucoma diagnosis is based on several direct and indirect assessments of the eye. ...
-
Chapter and Conference Paper
Bagging Tree Classifiers for Glaucoma Diagnosis
The aggregation of multiple unstable classifiers leads to substantial reduction of misclassification error in many applications and bench mark problems. We focus on the problem of classifying eyes as normal or...
-
Chapter and Conference Paper
Bioinformatics and Classification: The Analysis of Genome Expression Data
The availability of microarray data caused a new interest in clustering and classification methods. DNA microarrays are likely to play an important role for diagnosis and prognosis in clinical practice. Using ...
-
Chapter and Conference Paper
Bagging Combined Classifiers
Aggregated classifiers have proven to be successful in reducing misclassification error in a wide range of classification problems. One of the most popular is bagging. But often simple procedures perform comp...
-
Article
Urinary calcium excretion in healthy children and adolescents
Urinary calcium (Ca) excretion was determined in 1,578 24-h urine samples from 507 healthy children and adolescents (252 boys, 255 girls; 2.8–18.4 years) participating in the DONALD Study and is presented for ...
-
Article
A high-resolution radiation hybrid map of the proximal region of rat Chromosome 4
Radiation hybrid (RH) map** has been used to produce genome maps in the human and mouse, but as yet the technique has been applied little to other species. We describe the use of RH map** in the rat, usin...
-
Chapter and Conference Paper
Classification and Data Analysis in Genome Projects: Some Aspects of Map**, Alignment and Tree Reconstruction
Some statistical aspects of classification and data analysis in genome projects are reviewed and discussed. The construction of genetic maps involves sedation and hierarchical classification problems. The alig...
-
Chapter and Conference Paper
Exploration Homologer Sequenzdaten: Positionelle Mutationsrate, Genetische Distanz und Phylogenie
In der Literatur findet man vielfältige biologische und mathematische Modelle der evolutionären Interpretation von genetischen Sequenzdaten. Eine Übersicht über neuere Entwicklungen liefern beispielsweise Fels...
-
Chapter and Conference Paper
Reconstruction of Phylogenies by Distance Data: Mathematical Framework and Statistical Analysis
The reconstruction of phylogenies is an important problem in biological systematics since Darwin recognized natural selection as scientific cause of biological evolution. Since the early beginnings, cp. Haecke...
-
Chapter and Conference Paper
Exploring Homologous tRNA Sequence Data: Positional Mutation Rates and Genetic Distance
The literature provides different proposals for mathematical or biological models for the evolutionary interpretation of sequence data. For example Felsenstein (1983) or Weir (1985, 1988a) reviewed the state o...
