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Article
Open AccessStudies of new Higgs boson interactions through nonresonant HH production in the \( b\overline{b}\gamma \gamma \) final state in pp collisions at \( \sqrt{s} \) = 13 TeV with the ATLAS detector
A search for nonresonant Higgs boson pair production in the b b
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Article
Open AccessSearch for direct production of electroweakinos in final states with one lepton, jets and missing transverse momentum in pp collisions at \( \sqrt{s} \) = 13 TeV with the ATLAS detector
Searches for electroweak production of wino-like chargino pairs, χ ...
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Article
Open AccessAutophagy of OTUD5 destabilizes GPX4 to confer ferroptosis-dependent kidney injury
Ferroptosis is an iron-dependent programmed cell death associated with severe kidney diseases, linked to decreased glutathione peroxidase 4 (GPX4). However, the spatial distribution of renal GPX4-mediated ferr...
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Article
Open AccessStudies of the decay \( {\textrm{D}}_{\textrm{s}}^{+}\to {\textrm{K}}^{+}{\textrm{K}}^{-}{\mu}^{+}{\nu}_{\mu } \)
The D s + → ...
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Article
Open AccessIdentifying a locus in super-enhancer and its resident NFE2L1/MAFG as transcriptional factors that drive PD-L1 expression and immune evasion
Although the transcriptional regulation of the programmed death ligand 1 (PD-L1) promoter has been extensively studied, the transcription factor residing in the PD-L1 super-enhancer has not been comprehensivel...
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Article
Open AccessA systematic review on automated clinical depression diagnosis
Assessing mental health disorders and determining treatment can be difficult for a number of reasons, including access to healthcare providers. Assessments and treatments may not be continuous and can be limit...
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Article
Open AccessAssociation between antenatal corticosteroid treatment and severe adverse events in pregnant women
Antenatal corticosteroids are considered the standard of care for pregnant women at risk for preterm birth, but studies examining their potential risks are scarce. We aimed to estimate the associations of ante...
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Article
Open AccessTargeting histone deacetylase-3 blocked epithelial-mesenchymal plasticity and metastatic dissemination in gastric cancer
Histone deacetylase (HDAC) inhibitors (HDIs) can modulate the epithelial-mesenchymal transition (EMT) progression and inhibit the migration and invasion of cancer cells. Emerging as a novel class of anti-cance...
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Article
Open AccessMeasurement of the branching fraction of \( {\textrm{D}}_{\textrm{s}}^{+} \) → τ+ντ via τ+ → μ+νμ \( \overline{\nu} \) τ
Utilizing 7.33 fb−1 of e+e− collision data taken at the center-of-mass energies of 4.128, 4.157, 4.178, 4.189, 4.199, 4.209, 4.219, and 4.226 GeV with the BESIII detector, the branching fraction of the leptonic d...
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Article
The Aging Biomarker Consortium represents a new era for aging research in China
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Article
Open AccessALKBH5 promotes hypopharyngeal squamous cell carcinoma apoptosis by targeting TLR2 in a YTHDF1/IGF2BP2-mediated manner
Hypopharyngeal squamous cell carcinoma (HPSCC) is one of the most aggressive cancers and is notorious for its extremely poor prognosis. However, very few molecular biological studies have been performed. As a ...
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Article
Open AccessIdentifying causal genes for migraine by integrating the proteome and transcriptome
While previous genome-wide association studies (GWAS) have identified multiple risk variants for migraine, there is a lack of evidence about how these variants contribute to the development of migraine. We emp...
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Article
Open AccessExosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG1
Tumor-derived exosomes and their contents promote cancer metastasis. Phosphoglycerate mutase 1 (PGAM1) is involved in various cancer-related processes. Nevertheless, the underlying mechanism of exosomal PGAM1 ...
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Article
Yinlai Decoction Protects Microstructure of Colon and Regulates Serum Level of D-Lactic Acid in Pneumonia Mice Fed with High-Calorie and High-Protein Diet
To investigate the effect of Yinlai Decoction (YD) on the microstructure of colon, and activity of D-lactic acid (DLA) and diamine oxidase (DAO) in serum of pneumonia mice model fed with high-calorie and high-...
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Article
STING is a cell-intrinsic metabolic checkpoint restricting aerobic glycolysis by targeting HK2
Evasion of antitumour immunity is a hallmark of cancer. STING, a putative innate immune signalling adaptor, has a pivotal role in mounting antitumour immunity by coordinating innate sensing and adaptive immune...
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Article
Open AccessCombination of inclusive top-quark pair production cross-section measurements using ATLAS and CMS data at \( \sqrt{s} \) = 7 and 8 TeV
A combination of measurements of the inclusive top-quark pair production cross-section performed by ATLAS and CMS in proton–proton collisions at centre-of-mass energies of 7 and 8 TeV at the LHC is presented. ...
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Article
A quick online cross-sectional study of knowledge, attitude, practice, and information media toward the Omicron pandemic in China
The knowledge, attitudes, and practices (KAP) toward the COVID-19 and popular information media of the public is unclear in the late pandemic. The objective of this study was to evaluate the Chinese residents’...
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Article
Analytical Methods, Occurrence, Fate, and Toxicity of Ethylmercury in the Environment: Review and Outlook
Studies on the environmental fate and risk of mercury (Hg) have been mostly focused on total mercury and a very toxic species methylmercury (MeHg). However, another organic Hg species, ethylmercury (EtHg), has...
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Article
Biomarkers of aging
Aging biomarkers are a combination of biological parameters to (i) assess age-related changes, (ii) track the physiological aging process, and (iii) predict the transition into a pathological status. Although ...
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Article
Challenges and Strategies to Enhance the Systemic Absorption of Inhaled Peptides and Proteins
Proteins and peptides-based therapeutics are making substantial access to the market due to their obvious advantages of strong potency, high specificity and desirable safety profile. However, most clinical pro...
